Doctor insights on:
Medicine For Sickle Cell Carrier
Usually no: The sc carrier state is associated with normal hematological values and normal life span. Knowledge of carrier status is important for reproductive planning since carriers can have children with sickle cell disease. Although uncommon, persons who are carriers for sickle cell may develop specific rare symptoms that may be related to sickle cell trait. ...Read more
I just took a sickle cell screen and result was negative. Does that mean I'm not a sickle cell carrier-aa genotype?
Means no Hgb S: This test is specifically looking for HGB s. It will detect sickle trait (hgb as) or sickle cell disease (hgb ss). If the test is negative it means there is no sickle hemoglobin present, but it does not mean aa. There are many abnormal hemoglobins that are not aa, but would also test negative on a sickle screen. ...Read more
It Shouldn't Be!: Patients with sickle cell trait (carriers) are at minimal risk of developing any clinical problems except under very severe environmental conditions. Strange things can always happen, but a good anesthesiologist should be able to get a patient with sickle cell trait through any operation safely. ...Read more
Yes: Or one with trait and one with ss. ...Read more
If me and boyfriend both have sickle cell trait, how will we prevent our children from having full sickle cell anemia?
Nothing: Unfortunately, there would be 25% chance for your child to have sickle cell disease and 50% chance for sickle cell trait. With our technology now, nothing can alter the risk. Sorry to say, the only thing for somebody with sickle cell trait to completely prevent any possibility of having a biological child with sickle cell disease is by having a child with somebody with normal hb. ...Read more
Can a father with normal blood and a mother with sickle cell trait have a child with sickle cell anemia?
Mutated gene: It is believed a single gene mutation occurred hundreds of years ago in a person in sub-Saharan Africa. When carried as one of a pair (trait), it seemed to confer resistance to malaria. It is transmitted as a recessive gene, meaning the normal gene next to it can do the work. When 2 defective genes are present, (sickle cell disease) the proper work is not done and the blood cells are defective. ...Read more
Usually none: Having sickle cell trait means being a carrier for a mutation in one of the hemoglobin genes. It usually does not give any symptoms, but is able to be transmitted to ones children. If the other parent also has sickle cell trait or sickle cell anemia, then the children are at risk for possibly inheriting sickle cell anemia. ...Read more
No: Sickle cell trait is when a person has one mutated copy of the beta-hemoglobin gene and one normal copy. You always inherit the mutated hemoglobin from one of your parents. Thus, one parent always has at least sickle cell trait if the child has sickle cell trait. Therefore trait does not skip a generation. ...Read more
Not really: If it were not for the newborn screening done in all states we would not pick up these kids in childhood. These kids have pretty normal lives. If/ when their parents are aware they carry trait, we would look for it at some point but there would not be any urgency beyond the desire to know. ...Read more
Check this out:: Http://www. Cdc. Gov/ncbddd/sicklecell/documents/scd%20factsheet_sickle%20cell%20trait. Pdf.Get a more detailed answer ›
Genes: Sickle cell anemia occurs when someone has 2 sickle cell genes. Normal hemoglobin (hb) genes code for hb a. A sickle cell gene codes for hb s. Having 1 hb a gene & 1 hb s gene leads to sickle trait. This will have no symptoms, but has some health consequences. 2 genes for hb s leads to sickle cell anemia. To make things more complicated, there are other abnormal hb genes that can cause problems. ...Read more
It is inherited: Hemoglobin (HGB) is a complicated chemical that is in the red blood cells and carries oxygen. We inherit one gene from each parent that makes one of the parts of HGB called beta chains. If we inherit a sickle beta chain gene from one parent and a normal beta chain gene from the other, we have sickle trait. If we inherit a sickle beta chain gene from both parents, we have sickle cell anemia. ...Read more
Straightforward: The beta globin gene is on chromosome 11. Everyone has two, one from each parent. If you have sickle trait, one is normal and the other has the sickle mutation. Half your germ cells (eggs or sperm) will carry the normal gene, half the mutated gene. If you give the mutated gene to your child, they have sickle trait. If they get a mutated gene from your partner too, they have sickle cell disease. ...Read more
Sickle trait: Sickle trait means one copy of hemoglobin carries the mutation for sickle cell disease and the other copy is unaffected. Most people with sickle trait are unaffected by this. For athletes with sickle trait, it is essential to keep well hydrated. See http://www. Cdc. Gov/ncbddd/sicklecell/traits. Html for good recommendations. ...Read more
No: Look for another explanationGet a more detailed answer ›
Nothing: Sickle cell disease causes anemia, pain crises, susceptibility to certain infections, and more. It's a recessive condition, which means you have to inherit two beta-globin mutations to have scd. If you inherit just one, you have sickle cell trait, and that does not cause noticeable signs or symptoms. Under extraordinary circumstances, sc trait can cause problems, but for most folks nothing. ...Read more
Less severe than SS: Hemoglobin sc disease is the second most common type of sickle cell disease. It occurs when you inherit the hb c gene from one parent and the hb s gene from the other. Individuals with hb sc have similar symptoms to individuals with hb ss (sickle cell disease). However, the anemia is less severe. ...Read more
Trait is asymptomatc: A person with as hemoglobin (sickle cell trait is almost always asymptomatic themselves but can pass the mutated gene onto their children. A person with sshemoglobin (sickle cell anemia) is also sometimes asymptomatic, but often develops some symptoms including: anemia, fatigue, pain, slow growth, increased incidence of infection crises, etc. ...Read more
How likely am I to have sickle cell trait if my parents, grandparents, and greatgrandparents are nonafrican?
Genetic condition: While it is true that sickle cell in most common in those with african ancestry, people from other locations can carry the gene. The more important factor is not whether your ancestors are non-african but whether they carry the gene for sickle cell. If they don't, then you cannot get the condition. ...Read more