Doctor insights on:
Medicine For Seminoma
Testicular cancer.: Seminoma is a form of testicular cancer, and is the most common type. Compared to other forms of testicular cancer it has a good prognosis, with cure rates in excess of 90%. 15% of the time, it makes a marker called beta-hcg that can be detected in the blood. It is highly sensitive to chemotherapy and radiation, and can also be cured with surgery. ...Read more
Seminoma: A form of testicular cancer which is made by pathologic evaluation. It responds to removal of affected testicle and radiation. ...Read more
Very low: Seminoma can be cured with modern treatments. If it stays under control for more than 5 years, the cure likelihood is >95%. So the odds of relapse are less than 5%. ...Read more
Growth rate: Seminoma grow at varying rates but the rise in the beta HCG usually corresponds to the growth of the tumor. If b-hcg doubles in 6 months, then the tumor doubles in size. No all seminoma secret b-hcg but it is a simple test on growth other than ct size of any known tumor. ...Read more
How much faster does non seminoma tc grow than seminoma tc? How much will they untreated grow in a year?
Testicular cancer: Non seminoma tc grows faster than seminoma in most circumstances, there is no way to tell with certainty how fast any of these tumors will grow in a year if left untreated. The real question here is why wait, if you have one, no matter what kind, get treatment asap. ...Read more
See answer: The following link is a good explanation of the potential side effects of Etoposide and cisplatin: a commonly used regimen for stage 2 seminoma. Best wishes. Http://www. Macmillan. Org. Uk/cancerinformation/cancertreatment/treatmenttypes/chemotherapy/combinationregimen/etoposidecisplatin. Aspx. ...Read more
HCG: This and PLAP (placental alkaline phosphatase) are often elevated in the presence of seminoma, but they are neither sensitive nor specific. There is no good blood test to search for cancer in general -- everything that's been tried ends up generating more morbidity from unnecessary procedures than the few lives saved are probably worth. Routine cancer screening is still the best appraoch. ...Read more
I am starting chemo for seminoma in stage 2a (non bulky) in 3 days, what should I expect other than hairloss and vomitting?
Depends: I recommend to you review chemo you taking on line, but in general they can cause nausea, vomiting, but good drugs available to prevent and treat if needed, you can feel tired, get poor apetite, diarrea, sore moth, etc etc, poor sleep sometimes. And maybe more depending on specific side effects of each chemo. ...Read more
I took 3 cycles of EP for stage 2 seminoma which was clear on PET about a year ago. I am thinking to do scuba PADI open water course. Will it be ok?
Yep: Check with your Urologist. But should be OK ...Read more
I finished my ep 4 cycles for seminoma a month ago. My blood work seems to be ok but monocyte count is rising at every test. Now it is 14.1 is it ok?
See MD: You need regular md visits to pick up tumors early. ...Read more
What is the treatment for seminoma if it is only find at paraaortic lymph node? And what is the duration?
Depends: Some cases of seminoma can present as a primary tumour outside the testis, most commonly in the mediastinum. It is usually managed with radiation and chemotherapy and often requires orchiectomy, but without knowing your overall evaluation and extent of disease it is best answered by your oncologist or urologist. ...Read more
Have read the doubling time for nonseminoma testicular cancer is 10-30 days. What's the doubling time for seminoma?
Can't say: You need to consult with an oncologist for this answer. There are many variables. Ask your family physician for a referral. ...Read more
I recently completed my chemo for seminoma stage 2, 4 cycles of ep. What shouldn't I eat? I heard that beef and grapes arnt good
Eat anything healthy: You are in 'negative nitrogen balance' now which is why you have fatigue, get full early, take naps everyday, and the food looks and smells funny. I start all patients on 'milkshakes' daily. The body burns glycogen (sugar) for energy but chemo and surgery causes you to exhaust the glycogen stores of the body in 18 hours. Milkshakes have 1.0 calorie/cc of glucose and reverses the problem w/in a day. ...Read more
Different tumors: Over 90% of testis tumors are germ cell tumors which are seminoma, non-seminoma or mixed depending on the type of malignant cell. Classic seminoma is the most common testis tumor in adults. Almost all testis tumors are initially treated by surgical removal (orchiectomy). Then, based on the type of tumor and stage (aggressive characteristics, spread to lymph nodes) determines next treatment. ...Read more
Will I need chemo or radiation? A seminoma smaller than a marble was removed from my testis a month ago. And yesterday the whole testis.
Tough: If they thought it was cancer, should have had a orchiectomy at diagnosis. We do not remove masses from the testicle if concern for malignancy. You will need a ct scan of the abdomen/pelvis and serum markers. Also a chest x-ray. If pure seminoma and limited to testicle, either radiation or 1 cycle of carboplatin. Ct scans first! ...Read more
Post op seminoma, in r testicle. Pet scan done for suspecious nodes. Pet scan result shows negative for any abnormalility. This means no seminoma?
Surveillance: A negative pet scan means there is no accumulation of cancer cells large enough to be discernible by the pet scanner. There is a resolution limit of about 7mm in size to be seen, some are better now. I am not trying to scare you, but your doctor I'm sure will continue to caution you and continue surveillance for a period of time safe to say you are cancer-free. ...Read more
It has been a year since I completed EP 3 cycles for stage 2 seminoma. I am doing well, active and working full time. What will be my next step? CT?
Repeat imaging: A repeat CT or PET/CT will be needed to assess how effective the EP chemo was in downstaging your tumor burden. Please followup with your oncologist for this repeat staging. ...Read more
I had a seminoma cancer. I got my semen's analysis done but there was no sperm (azospermia). Can you please tell me if I'm having azosperia because of cancer?
Can spread: Can spread to any part of the body including the brain ; need full body scan to eval. ...Read more
Undecended right testicle and found seminoma, azoospermia in two samples with in 3 weeks. Left testicle normal in ultrasound scan. Am I sterile?
Possibly: Sorry to hear about your recent diagnosis. Good news is that seminoma and testicular cancer in general almost always curable nowadays especially in early stages. Assuming your semen collections were correctly obtained and tested, complete absence of sperm (azoospermia) implies sterility. Would certainly recommend that this be evaluated further to determine cause especially in view of normal us. ...Read more
R intra abdominal testisicle post op. Path shows seminoma. Solitary interaortocaval lymph node 2.3*2.3 CM reduced to 2*1.5. Is it seminoma spreading?
I had classical seminoma in right testis. I was treated by surgery and radiation now after two year AFP markr is elevated im I having another tumer?
Need Imaging: AFP is not elevated by seminoma. It is possible that your initial tumor contained non-seminoma elements. AFP can also be elevated by other medical conditions. First thing is to recheck the AFP to be sure this is a real finding. Then you need to have surveillance imaging to evaluate for metastases. It is imperative that you have careful follow-up. ...Read more
Does 2xbep chemo is enough for non-seminoma (embrional with yolk sac tumor) with clear scan, little elevated bhcg (25) and normal AFP or should 3xbep?
It depends: It depends on the total number of bep cycles already given. Most patients are treated with a total of 3 (low risk patients) or 4 cycles of bep for high risk (bulky disease). The general rule if to use 2 more cycles after achieving a complete response (cr). ...Read more
Right testicle operated showed seminoma. Ct showed enlarged paraaortic lymph node. Does this means metastatis or due to surgery?
Seminoma can occur in testes or the mediastinum as the primary tumor, it is classified as one of the germ cell tumors.
If there is regional paraaortic node histooogic involvement if usually is metastasis. Chemotherapy and/or radiation has very good cure rate even with metastases. At surgery they sample the regional nodes for involvement to determine best treatment for patient. ...Read more
Operated undecended testicle showed tumor cells. Enlarged paraaortic lymph node in ct. But tumor markers normal. High alt (67). Is it still seminoma?
In situ?: The diagnosis of seminoma is made on examination of tissue by the pathologist; tumor markers and imaging are ancillary studies. An undescended testis often has premalignant cells lining the tubules; these are not yet cancer and if gone will not be troublesome. If you were told there was indeed an actual seminoma, that's a different story & you may require followup such as biopsy of the node. ...Read more