Top
30
Doctor insights on: Medicine For Seminoma

Share
1

1
Characteristics of the seminoma?

Characteristics of the seminoma?

Testicular cancer.: Seminoma is a form of testicular cancer, and is the most common type. Compared to other forms of testicular cancer it has a good prognosis, with cure rates in excess of 90%. 15% of the time, it makes a marker called beta-hcg that can be detected in the blood. It is highly sensitive to chemotherapy and radiation, and can also be cured with surgery. ...Read more

Dr. Janice Alexander
32 Doctors shared insights

Seminoma (Definition)

A form of testicular cancer which is made by pathologic evaluation. It responds to removal of ...Read more


2

2
What is the definition or description of: seminoma?

What is the definition or description of: seminoma?

Seminoma: A form of testicular cancer which is made by pathologic evaluation. It responds to removal of affected testicle and radiation. ...Read more

3

3
What is the relapse rate of cured mediastinal seminoma after 5 years?

What is the relapse rate of cured mediastinal seminoma after 5 years?

Very low: Seminoma can be cured with modern treatments. If it stays under control for more than 5 years, the cure likelihood is >95%. So the odds of relapse are less than 5%. ...Read more

4

4
Is it possible to have undetected seminoma tc for 2 years? How fast do they grow?

Is it possible to have undetected seminoma tc for 2 years? How fast do they grow?

Growth rate: Seminoma grow at varying rates but the rise in the beta HCG usually corresponds to the growth of the tumor. If b-hcg doubles in 6 months, then the tumor doubles in size. No all seminoma secret b-hcg but it is a simple test on growth other than ct size of any known tumor. ...Read more

5

5
How much faster does non seminoma tc grow than seminoma tc? How much will they untreated grow in a year?

How much faster does non seminoma tc grow than seminoma tc? How much will they untreated grow in a year?

Testicular cancer: Non seminoma tc grows faster than seminoma in most circumstances, there is no way to tell with certainty how fast any of these tumors will grow in a year if left untreated. The real question here is why wait, if you have one, no matter what kind, get treatment asap. ...Read more

6

6
Starting 4 cycles of ep for pure seminoma stage 2, what should I expect as side effects?

Starting 4 cycles of ep for pure seminoma stage 2, what should I expect as side effects?

See answer: The following link is a good explanation of the potential side effects of Etoposide and cisplatin: a commonly used regimen for stage 2 seminoma. Best wishes. Http://www. Macmillan. Org. Uk/cancerinformation/cancertreatment/treatmenttypes/chemotherapy/combinationregimen/etoposidecisplatin. Aspx. ...Read more

7

7
What r the chances of cancer in child if father has seminoma?

What r the chances of cancer in child if father has seminoma?

Not high 1-3%: Approximately 1 to 3 percent of affected men have a family member with the disease.
Majority would be associated with some other factors- like undescended testes, infertility/subfertility, HIV infection, hypospadias, other condition like klinefelter's etc. ...Read more

8

8
Is there any relation between azoospermia and seminoma cancer?

Is there any relation between azoospermia and seminoma cancer?

Low sperm counts: Are common in men with testis cancer, seminoma and non-seminoma. Reason is not clear. Some believe there is a developmental issue, undescended testis also at higher risk, others blame anesthetics. Truth be known, we do not know. ...Read more

9

9
What kind of blood test should be done for seminoma and malignancy?

What kind of blood test should be done for seminoma and malignancy?

HCG: This and PLAP (placental alkaline phosphatase) are often elevated in the presence of seminoma, but they are neither sensitive nor specific. There is no good blood test to search for cancer in general -- everything that's been tried ends up generating more morbidity from unnecessary procedures than the few lives saved are probably worth. Routine cancer screening is still the best appraoch. ...Read more

10

10
I am starting chemo for seminoma in stage 2a (non bulky) in 3 days, what should I expect other than hairloss and vomitting?

Depends: I recommend to you review chemo you taking on line, but in general they can cause nausea, vomiting, but good drugs available to prevent and treat if needed, you can feel tired, get poor apetite, diarrea, sore moth, etc etc, poor sleep sometimes. And maybe more depending on specific side effects of each chemo. ...Read more

13

13
Seminoma tumour - testicular cancer, what to do?

Seminoma tumour - testicular cancer, what to do?

Orchiectomy: Lesion requires resection by orchiectomy with spermatic cord. Prior to this PET/CAT helpful since this tumor spreads quickly to para aortic nodes and may require chemo or RT depending on node size followed by chemotherapy. Cure rate high for this type of germ cell lesion. ...Read more

15

15
What is the treatment for seminoma if it is only find at paraaortic lymph node? And what is the duration?

What is the treatment for seminoma if it is only find at paraaortic lymph node? And what is the duration?

Depends: Some cases of seminoma can present as a primary tumour outside the testis, most commonly in the mediastinum. It is usually managed with radiation and chemotherapy and often requires orchiectomy, but without knowing your overall evaluation and extent of disease it is best answered by your oncologist or urologist. ...Read more

16

16
Have read the doubling time for nonseminoma testicular cancer is 10-30 days. What's the doubling time for seminoma?

Have read the doubling time for nonseminoma testicular cancer is 10-30 days. What's the doubling time for seminoma?

Can't say: You need to consult with an oncologist for this answer. There are many variables. Ask your family physician for a referral. ...Read more

17

17
I recently completed my chemo for seminoma stage 2, 4 cycles of ep. What shouldn't I eat? I heard that beef and grapes arnt good

I recently completed my chemo for seminoma stage 2, 4 cycles of ep. What shouldn't I eat? I heard that beef and grapes arnt good

Eat anything healthy: You are in 'negative nitrogen balance' now which is why you have fatigue, get full early, take naps everyday, and the food looks and smells funny. I start all patients on 'milkshakes' daily. The body burns glycogen (sugar) for energy but chemo and surgery causes you to exhaust the glycogen stores of the body in 18 hours. Milkshakes have 1.0 calorie/cc of glucose and reverses the problem w/in a day. ...Read more

18

18
What is the difference between seminoma and nonseminoma cancer of the testicles?

What is the difference between seminoma and nonseminoma cancer of the testicles?

Different tumors: Over 90% of testis tumors are germ cell tumors which are seminoma, non-seminoma or mixed depending on the type of malignant cell. Classic seminoma is the most common testis tumor in adults. Almost all testis tumors are initially treated by surgical removal (orchiectomy). Then, based on the type of tumor and stage (aggressive characteristics, spread to lymph nodes) determines next treatment. ...Read more

19

19
What would be the better treatment for classical seminoma: radiation therapy or chemotherapy?

What would be the better treatment for classical seminoma: radiation therapy or chemotherapy?

Depends on stage.: Stage 1 and nonbulky stage 2: radiation therapy appears preferable. Single agent Carboplatin is being looked at.

Bulky stage 3 and stage 3: 4 cycles of chemotherapy with bleomycin, Etoposide and Cisplatin is standard.

Stage 4: chemotherapy. ...Read more

20

20
Will I need chemo or radiation? A seminoma smaller than a marble was removed from my testis a month ago. And yesterday the whole testis.

Will I need chemo or radiation? A seminoma smaller than a marble was removed from my testis a month ago. And yesterday the whole testis.

Tough: If they thought it was cancer, should have had a orchiectomy at diagnosis. We do not remove masses from the testicle if concern for malignancy. You will need a ct scan of the abdomen/pelvis and serum markers. Also a chest x-ray. If pure seminoma and limited to testicle, either radiation or 1 cycle of carboplatin. Ct scans first! ...Read more

21

21
Post op seminoma, in r testicle. Pet scan done for suspecious nodes. Pet scan result shows negative for any abnormalility. This means no seminoma?

Post op seminoma, in r testicle. Pet scan done for suspecious nodes. Pet scan result shows negative for any abnormalility. This means no seminoma?

Surveillance: A negative pet scan means there is no accumulation of cancer cells large enough to be discernible by the pet scanner. There is a resolution limit of about 7mm in size to be seen, some are better now. I am not trying to scare you, but your doctor I'm sure will continue to caution you and continue surveillance for a period of time safe to say you are cancer-free. ...Read more

22

22
It has been a year since I completed EP 3 cycles for stage 2 seminoma. I am doing well, active and working full time. What will be my next step? CT?

Repeat imaging: A repeat CT or PET/CT will be needed to assess how effective the EP chemo was in downstaging your tumor burden. Please followup with your oncologist for this repeat staging. ...Read more

23

23
I had a seminoma cancer. I got my semen's analysis done but there was no sperm (azospermia). Can you please tell me if I'm having azosperia because of cancer?

I had a seminoma cancer. I got my semen's analysis done but there was no sperm (azospermia). Can you please tell me if I'm having azosperia because of cancer?

Chemo?: Seminoma can be treated with chemo and radiation. If you had chemo, you may be infertile for a couple of years and sometimes permanently. Radiation can cause damage to the remaining testicle but it's usually left out of the radiation field. You need a male fertility specialist. ...Read more

24

24
Does non seminoma testicular cancer made up of embryonic and yolk sac spread and where to?

Can spread: Can spread to any part of the body including the brain ; need full body scan to eval. ...Read more

25

25
Undecended right testicle and found seminoma, azoospermia in two samples with in 3 weeks. Left testicle normal in ultrasound scan. Am I sterile?

Undecended right testicle and found seminoma, azoospermia in two samples with in 3 weeks. Left testicle normal in ultrasound scan. Am I sterile?

Possibly: Sorry to hear about your recent diagnosis. Good news is that seminoma and testicular cancer in general almost always curable nowadays especially in early stages. Assuming your semen collections were correctly obtained and tested, complete absence of sperm (azoospermia) implies sterility. Would certainly recommend that this be evaluated further to determine cause especially in view of normal us. ...Read more

27

27
I had classical seminoma in right testis. I was treated by surgery and radiation now after two year AFP markr is elevated im I having another tumer?

I had classical seminoma in right testis. I was treated by surgery and radiation now after two year AFP markr is elevated im I having another tumer?

Need Imaging: AFP is not elevated by seminoma. It is possible that your initial tumor contained non-seminoma elements. AFP can also be elevated by other medical conditions. First thing is to recheck the AFP to be sure this is a real finding. Then you need to have surveillance imaging to evaluate for metastases. It is imperative that you have careful follow-up. ...Read more

28

28
Does 2xbep chemo is enough for non-seminoma (embrional with yolk sac tumor) with clear scan, little elevated bhcg (25) and normal AFP or should 3xbep?

Does 2xbep chemo is enough for non-seminoma (embrional with yolk sac tumor) with clear scan, little elevated bhcg (25) and normal AFP or should 3xbep?

It depends: It depends on the total number of bep cycles already given. Most patients are treated with a total of 3 (low risk patients) or 4 cycles of bep for high risk (bulky disease). The general rule if to use 2 more cycles after achieving a complete response (cr). ...Read more

29

29
Right testicle operated showed seminoma. Ct showed enlarged paraaortic lymph node. Does this means metastatis or due to surgery?

Right testicle operated showed seminoma. Ct showed enlarged paraaortic lymph node. Does this means metastatis or due to surgery?

Usually metastasis: Seminoma can occur in testes or the mediastinum as the primary tumor, it is classified as one of the germ cell tumors.
If there is regional paraaortic node histooogic involvement if usually is metastasis. Chemotherapy and/or radiation has very good cure rate even with metastases. At surgery they sample the regional nodes for involvement to determine best treatment for patient. ...Read more

30

30
Operated undecended testicle showed tumor cells. Enlarged paraaortic lymph node in ct. But tumor markers normal. High alt (67). Is it still seminoma?

Operated undecended testicle showed tumor cells. Enlarged paraaortic lymph node in ct. But tumor markers normal. High alt (67). Is it still seminoma?

In situ?: The diagnosis of seminoma is made on examination of tissue by the pathologist; tumor markers and imaging are ancillary studies. An undescended testis often has premalignant cells lining the tubules; these are not yet cancer and if gone will not be troublesome. If you were told there was indeed an actual seminoma, that's a different story & you may require followup such as biopsy of the node. ...Read more