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Doctor insights on: Medicine For Retinoblastoma

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What is retinoblastoma?

What is retinoblastoma?

Child eye cancer: Retinoblastoma is a malignant tumor of the retina which is seen in children. It currently has one of the highest cure rates of all childhood cancers 95-98%. It used to be treated by removal of the affected eye or radiation, but now more advanced eye sparing techniques are successful. ...Read more

Dr. Steven Bowers
208 doctors shared insights

Retinoblastoma (Definition)

Congenital malignant neoplasms that arise from the nuclear ...Read more


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What is retinoblastoma?

What is retinoblastoma?

Tumor: Retinblastoma is an intraocular tumor that usually affects children from birth through the early teens. It is usually treated successfully, but often requires removal of the affected eye. Rarely it is bilateral. It is iften dianosed when the pupil changes from a dark to whitish color, or when the red reflex in flash pictures is missing in one eye. ...Read more

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What causes retinoblastoma?

What causes retinoblastoma?

Retinoblastoma: Some cases are inherited and some cases are the result of spontaneous mutations of the retinoblastoma gene. ...Read more

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How is retinoblastoma cured?

Aggressive: Depends on size and location, small tumors are treated with laser surgery. Radiation for larger tumors. Chemotherapy if tumor has spread beyond the eye. The eye may need to be removed if the tumor does not respond to other treatments. If cancer has not spread beyond the eye, almost all patients can be cured. ...Read more

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How is a retinoblastoma caused?

How is a retinoblastoma caused?

Chromosme 13: Has a paired site where the rb gene lives. It can be inherited, or occur accidentally (sporadic) mutation. The rb gene loss leads to the eye tumor, but it is also is involved with other tumors, and its chromosomal location is close to a region associated with bone tumors. ...Read more

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What's trilateral retinoblastoma?

Rb affects the eye: And you would think that bilateral is easy, but some species have photosensitivity in the brain region corresponding to the pineal, and that is the third site. ...Read more

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What is retinoblastoma diagnosis?

Eye exam: It is diagnosed by an eye exam supported by imaging studies. No blood tests to diagnose it. Getting a good history, and physical exam are in order ...Read more

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How is a retinoblastoma diagnosed?

How is a retinoblastoma diagnosed?

Opthalmologist: Evaluation by an opthalmologist experienced in this area. ...Read more

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Can you tell me about retinoblastoma?

Yes...: Retinoblastoma is an eye cancer that begins in the retina — the sensitive lining on the inside of your eye. Retinoblastoma most commonly affects young children, but can rarely occur in adults. Retinoblastoma may occur in one or both eyes. There are good treatments if caught early and if it has not spread outside of the eye. ...Read more

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Can you have retinoblastoma at age 13?

90% of cases: Of retinoblastoma occur before the age of 5, with most occurring before the age of 2. The incidence declines steeply with increasing age, so retinoblastoma at age 13 would be exceedingly rare. ...Read more

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What are the tests for retinoblastoma?

See eye doc: Retinoblastoma can be seen easily by an eye doc. ...Read more

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Does retinoblastoma stay in one place?

Does retinoblastoma stay in one place?

No: This is a malignant tumor of the retinal elements. It grow like any malignancy, can spread in the eye or elsewhere. It needs immediate attention to prevent vision loss or death. It commonly is inherited so families need to be advised about it. It occurs in infancy or at birth but not in older age. ...Read more

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What are the odds to get retinoblastoma?

Low: Extremely low risk for adults, because the retinal cells stop dividing in childhood. People with heritable(germ line) retinoblastoma are at a higher risk for other cancers throughout their lives, making genetic testing very important. It affects smaller children. ...Read more

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What are the symptoms of retinoblastoma?

What are the symptoms of retinoblastoma?

Retinoblastoma: Retinoblastoma is a disease of infancy. The child will not/cannot report symptoms. The parent and pediatrician will watch for white pupillary reflex, eye deviation, eye redness, and will be especially alert if the family in question has a history of this inherited tumor. ...Read more

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How can I get trilateral retinoblastoma?

See below for info: Retinoblastoma is a cancer of the eye. Like other cancers, it occurs when a cell 'goes bad' -- ie turns malignant and keeps multiplying. Unilateral would be in one eye, bilateral would be in both eyes. Trilateral would mean in 3 eyes, which isn't possible, since you have only 2 eyes. ...Read more

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What should I know about retinoblastoma?

Rare tumor: This rare eye cancer is sometimes caused by a genetically inherited abnormality. These cancers should be treated by centers of excellence that specialize in treating this rare cancer. Surgery or radiation therapy (proton beam or brachytherapy) are the most common treatment options.
http://www.cancer.gov/cancertopics/types/retinoblastoma. ...Read more

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How can retinoblastoma usually be detected?

Eye exam: The classic way to pick it up is that when a ligh is shone into the eye... Instead of looking red (like in a bad photo) it will be white and that merits a visit with the eye specialist. ...Read more

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Does retinoblastoma affect tissues or organs?

Does retinoblastoma affect tissues or organs?

Retinoblastoma: 1. Trilateral retinoblastoma refers to bilateral retinoblastoma associated with an intracranial tumor in the pineal or suprasellar region. 2. There can be orbital extension of retinoblastoma. 3.
Intracranial dissemination occurs by direct extension through the optic nerve.4. Hematogenous (blood spread) metastases may develop in the bones, bone marrow, and less frequently, in the liver. ...Read more

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Could children with retinoblastoma still see?

Frequently: It depends upon when the tumor is detected. The earlier, the more useful retina is present and treatment is less invasive and destructive early in the course. Many with retinoblastoma now have normal vision and of course many only have the tumor in one eye so the other is totally normal. ...Read more

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Do children who have retinoblastoma still see?

Do children who have retinoblastoma still see?

Depends...: These rare tumors affect the retina, the main sensory organ at the back of the eye. Depending on the extent of the involvement of the tumor, the child will have varying degrees limited visual acuity. ...Read more

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What the symptoms of signs of a retinoblastoma?

Leukocoria : Leukocoria — loss of the red eye reflex, and strabismus -deviation of the eye due to muscle weakness are the most common symptoms. Other symptoms can include: decreased vision, inflammation, hemorrhage into the eye, change in color of the iris, glaucoma, cellulitis, eye pain, fever. ...Read more

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What kind of dr. Do you see about retinoblastoma?

Doctors: Your best bet is to go through your pediatric ophthalmologist, who will know the resources available in your area. Good luck. ...Read more

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What is retinoblastoma and how can it be treated?

Retinoblastoma: It is a rare malignancy of the eye called the retina, caused by a mutation in a gene controlling cell division, generally affects children under-age 6, most 1 to 2 years of age. Treatment depends on the size and location. Treatment may involve surgery +/- radiation +/- chemotherapy. Best to visit a specialized pendiatric cancer center. Best wishes to you. ...Read more

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Could you tell me about the disease retinoblastoma?

Could you tell me about the disease retinoblastoma?

Retinoblastoma: A retinoblastoma is a tumor in the back of the eye. Although it is very rare, newborns are screened for it at birth, and at subsequent well child checks by using an ophthalmoscope to detect any asymmetry in the light reflex off of the retina. ...Read more

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Can anyone tell me about the cause of retinoblastoma?

Can anyone tell me about the cause of retinoblastoma?

Inherited: Chromosoml defect. It can also be acquired. The gene code is located on the long arm of chromosome 13. It also is assoicated in a cell cycle pathway with other cancers, as it can be lost during life. Bilateral retinoblastoma is always inherited. ...Read more

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Do all retinoblastomas occur in babies and young children?

Do all retinoblastomas occur in babies and young children?

Most of the time: The most common age is 18-24 months, but it could also present in neonates and older kids. I had one patient last year that was 7 years old. ...Read more

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What are the areas of the body affected by retinoblastoma?

Retinoblastoma: It is important to understand the genetic implications of this cancer as it is commonly inherited, and if you are a survivor, you need to know your chances of passing it to your offspring. ...Read more

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