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Doctor insights on: Medicine For Renal Cell

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Hi this nagarjun this is wrt my dear friend anupam who is fighting with renal cell carcinoma in advanced stage. No medicine is working. Please help.

Hi this nagarjun this is wrt my dear friend anupam who is fighting with renal cell carcinoma in advanced stage. No medicine is working. Please help.

I'm so sorry: The best drugs for metastatic renal cell carcinoma are pazopanib, axitinib, sorafenib, and sunitinib. If these aren't working, then a clinical trial might be an option. But it sounds like your friend might die, and may already know that deep down. You can help by comforting, listening, and facing this together. It is a profound gift to be with someone at death, just like at birth. Be at peace. ...Read more

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Could teenagers have renal cell carcinoma?

Could teenagers have renal cell carcinoma?

Yes: It's not common. If it does appear, it raises suspicion for a hereditary predisposition (von hippel — lindau, others). There are a few pediatric kidney cancers that mimic common renal cell carcinoma clinically but are distinct pathologic entities. ...Read more

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How deadly is renal cell carcinoma?

How deadly is renal cell carcinoma?

Varies with stage: Fortunately many renal cell carcinomas are now being diagnosed at an early stage (when the tumor is small and doesn't invade any other structures) thanks to improvements in imaging (ct scan etc). If early stage, many patients do very well after the tumor is removed. However, as the stage of the tumor increases, the risk of the cancer behaving aggressively increases. So stage helps to predict. ...Read more

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What's renal cell cancer?

What's renal cell cancer?

Kidney malignancy: Renal cell cancer is a primary malignancy of the kidney. It may have a clear cell appearance on pathology. A nephrectomy is the primary choice of therapy. Renal cell cancer may show up in the lung as a lung mass. ...Read more

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Any advice for renal cell carcinoma?

Any advice for renal cell carcinoma?

Get a good md: Find a doctor you can trust. Get a second opinion if you feel the need to either confirm the treatment course or find a different path. Consider removal of tumor in kidney if possible. Treat sites of metastatic disease aggressively if possible. ...Read more

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What is done for renal cell carcinoma?

What is done for renal cell carcinoma?

Treat or observe: Renal carcinoma is a primarily surgical disease. Most patients likely benefit from excision of tumors with the option of partial kidney removal allowing preservation of renal function compared to total removal. Newer options for small tumors include thermal ablation where cold or heat destroys the tumor. In some patients with small tumors and poor health or old age, surveillance can be pursued. ...Read more

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Is there cure for renal cell carcinoma?

Is there cure for renal cell carcinoma?

Yes: If it is removable with surgery cure is very likely. Most patients do well with this cancer. ...Read more

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What are the tests for renal cell cancer?

What are the tests for renal cell cancer?

CT scan w. contrast: (iv contrast). Renal ultrasound will also demonstrate kidney tumors but not nearly the detail of ultrasound. Ultimate test is microscopic pathalogical examination of tumor after it has been removed. Good luck. ...Read more

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What stage is a 7 mm renal cell carcinoma?

What stage is a 7 mm renal cell carcinoma?

Most likely Stage I: All tumors are staged by the tumor, nodes, metastasis (staging system). Stage i kidney tumors are less than 7 CM in size and have no evidence of lymph node as well as distant metastasis. Stage ii tumors are larger than 7 CM and have no lymph node or distant metastasis. Stage iii tumors are locally advanced. Stage IV tumors have spread to lymph nodes or other organs. ...Read more

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What are the symptoms of renal cell cancer?

What are the symptoms of renal cell cancer?

Hematuria,pain,mass.: This cancer presents with a classic triad of hematuria, flank pain, and a flank mass, but in only about 10-20% of patients. The most common individual symptoms are hematuria (40%), flank pain (40%), palpable mass (33%), and weight loss (33%). Symptoms like erythrocytosis (3%), hypercalcemia (5%), and non-metastatic hepatic dysfunction (15%) can also occur. ...Read more

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Is it possible to have renal cell carcinoma and have a normal egfr?

Is it possible to have renal cell carcinoma and have a normal egfr?

?egfr??: Please avoid using abbreviations...they may have different meaning to different folks. Is this epidermal growth factor receptor(EGFR) that you are talking about? Or is this something related to GFR(glomerular filtration rate) which is a test for Kidney function???. Please clarify so that we can address your question properly. ...Read more

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I've had renal cell carsenoma with 60% of my left kidney taken. I was told I have a calsfied mass on what's left of the kidney now. I now have bloody?

Get seen now.: Your question is incomplete and I am assuming you mean that you have blood in your urine. Call your primary care doc or your oncologist or go to an urgent care or ER to be evaluated to find out what could be causing this. ...Read more

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The size of my renal cell carcinoma is 7.2 x 7.2 x 8 cm what should I do?

The size of my renal cell carcinoma is 7.2 x 7.2 x 8 cm what should I do?

See a Urologist: You should see a Urologist and a Medical Oncologist. Much information is needed on imaging and rate of growth and other factors. This won't resolve using the internet. ...Read more

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Can renal cell carcinoma spread to somebody's skin?

Can renal cell carcinoma spread to somebody's skin?

Unusual but possible: Metastasis (spread) to the skin is uncommon for renal cell carcinoma. Lung is a much moe common site of spread. However, skin metastasis has been described. In fact, there are patients who were originally diagnosed solely through the biopsy of a suspicious skin lesion. Fortunately, unusual skin lesions are often accessible for biopsy which should decrease the uncertainty of diagnosis. ...Read more

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Can renal cell carcinoma eventually spread to the skin?

Can renal cell carcinoma eventually spread to the skin?

Yes: Usually expands locally, then in veins, then lung is common. But when metastasis occurs it can end up secondarily anywhere. ...Read more

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What is the prognosis for stage 4 renal cell carcinoma?

What is the prognosis for stage 4 renal cell carcinoma?

Poor: Unfortunately even with chemo, stage IV renal cell has a short survival time. Some reasonably good chemo agents are coming available but present therapies may work for a while, then quit working. ...Read more

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Is there a cure for stage 4 renal cell carcinoma?

Is there a cure for stage 4 renal cell carcinoma?

Stage 4 renal CA: Not likely but depends on what type of renal cell CA it is. Stage 4 means it is outside of kidney which is bad.

Discuss with your team. ...Read more

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What is the earliest sensitive indicator of metastasis for renal cell carcinoma?

What is the earliest sensitive indicator of metastasis for renal cell carcinoma?

Not clear cut: There is no special test that is an early sensitive indicator. The current guidelines after removal of a kidney tumor is exam, ldh and other blood test and ct scan.
In many tumors we have found that routine testing is not a great help.
A key idea is that any symptoms that is new or worrisome should be investigated quickly. Target the test to the symptom. ...Read more

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What symptoms does someone with renal cell cancer have?

What symptoms does someone with renal cell cancer have?

It varies: Renal cell carcinoma (rcc) unfortunately is usually asymptomatic until it's advanced stage. If it causes symptoms, it may present as blood in the urine, flank pain. If it spreads to other organs, it can cause problems in those areas including bone pain, shortness or breath, fatigue. Not uncommonly, rcc is picked up incidentally on ct scan of the abdomen but there is no role for ct screening. ...Read more

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How much time can somebody survive with untreated renal cell carcinoma?

How much time can somebody survive with untreated renal cell carcinoma?

Why do you ask?: Little renal cell carcinomas are a fairly common incidental finding at autopsy and we have no idea how long they've been there. If one is symptomatic, there's no guessing survival time. In any decision about accepting treatment, an honest discussion about both length and quality of life is essential. ...Read more

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For what length of time can a person live with renal cell carcinoma (matastatic)?

Possibly curable: Sunitinib, a new multitargeted tyrosine-kinase inhibitor (TKI), has shown high activity in patients with metastatic renal cell carcinoma (mRCC) and has demonstrated improvement in survival of those patients with metastatic disease. Sunitinib inhibits the vascular endothelial growth factor (VEGF) receptor and other tyrosine kinases, including the platelet-derived growth factor (PDGF) and c-kit receptor at nanomolar concentrations. ...Read more

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For what length of time can somebody survive with untreated renal cell carcinoma?

Variable: There are many types of renal carcinomas and along with individual characteristics there is variability in survival times. See this site for more info.
http://www.cancer.gov/cancertopics/types/kidney. ...Read more

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What all can renal cell carcinoma spread to? And where would it most likely spread to first?

What all can renal cell carcinoma spread to? And where would it most likely spread to first?

Lymph nodes first: Most of the time renal cell cancer is not detected in early stages, 25%- 30% cases already has metastasis at the time of diagnosis. As tumor grows invades capsule and spread to lymph nodes, then spread to liver, bone, lungs and brain. ...Read more

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Should i be nervous that they found a 7cm. Or 7mm something around my left kidney? I have has renal cell carisoma stage 2 years ago they did a parti

Should i be nervous that they found a 7cm. Or 7mm something around my left kidney? I have has renal cell carisoma stage 2 years ago they did a parti

Worry won't help: 7mm and 7cm are hugely different--which is it? These bumps can be normal anatomy, cysts, abscess or tumors. If you are concerned, seek a biopsy from your physician to alleviate or confirm your suspicions and provide a diagnosis. With a positive history, you are right to be concerned, but not complacent. Worry will not change any outcome! ...Read more

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What is renal cell adenocarcinoma it was on my daughters death cerificate after she died in a car wreck along with multiple blunt force injuries i understand that part

What is renal cell adenocarcinoma it was on my daughters death cerificate after she died in a car wreck along with multiple blunt force injuries i understand that part

Here's what happened: It's fairly common for an adult who died unexpectedly in an accident to have something serious that was not known in life. I list all cancers that I find in accident victims on the death certificate, simply so the family will know and for the sake of public health records. I'm going to assume you didn't know the cancer was hiding in the kidney and that it was asymptomatic. I'm sorry about ur loss. ...Read more