Doctor insights on:
Medicine For Pseudohypoparathyroidism
Interesting!: Hi. That's a rare genetic disease! See an endocrinologist. Since pseudohypoparathyroidism presents with low serum calcium and calcitriol (the active form of vitamin D), these usually need to be replaced (serum calcium to the LOW end of normal so you don't lose too much calcium in the urine and get kidney stones). If you are right and you have it, you'll thrill some endocrinologist! All the best. ...Read more
Test PTH and calcium: Hi. Pseudohypoparathyroidism (PHP) is an uncommon genetic defect with faulty PTH receptor signaling. You should see an endocrinologist for exam (there may be characteristic physical exam findings) and measurement of calcium, phosphate, calcitriol, and PTH. In hypopara, PTH is low and calcium is low. In PHP, calcium is low and PTH is elevated. Good luck. ...Read more
What do you suggest if my symptoms are similar to those presented in a case of pseudohypoparathyroidism. How can I be sure?
Measure PTH: Hi. It's quite easy, really. Document low blood calcium, high blood phosphate, and high PTH in a patient who is short and has short fingers & toes, etc. It can tested for provocatively by injecting PTH (or teriparatide) and measuring urinary cyclic AMP. See an endocrinologist with an interest in calcium metabolism. Good luck! ...Read more
I don't think so.
I hope you are seeing an Endocrinologist for your pseudo hyperpara.
If not you must do so and ask about your nails. ...Read more
Should not be...: Pseudohypoparathyroidism (PHP) is a disorder of calcium sensing in the kidneys and bone (mult types) & leads to calcium wasting by the the kidneys. However, the possible genetic issues affect a protein that is found throughout the body and can lead to multiple endocrine probs and symptoms. Random fact about PHP is the same gene prob causes diff symptoms if inherited from mother or father. ...Read more
Pseudohypoparathyroidism? I have "archibald's sign, " chronic skin rash, constipation, heart flutter. Come home asap from vet school abroad for dx/tx?
You present a number of medical complaints, all of which need attention. Please start with a visit to your primary doctor. Your medical history will be taken, you will be examined by the doctor, and laboratory studies will be ordered. Once the information is collected your doctor will decide where you might go for further care.
Please let me know what develops. ...Read more
If Dr. (endocrinology) can get me in by end of yr, I'll fly to u. Believe to have pseudohypoparathyroidism. Dealing w/ sv muscle pain in legs, seizures, fit body type, labs fit (Calcium, Phosphorous, Albumin). Will allow study. [email protected] Com?
What are you doing?: First, are you sure this is the diagnosis? What labs have you had done & results? Are you on any treatment? This needs to be discussed more a diagnosis made and treatment may need to be started now. With a little more information some treatment should also be able to be started. This is also a life long disease and will need ongoing endo f/u. We should be able to get you in to one near home ...Read more
Depends...: .... As there are many types of pseudohypoparathyroidism. In some types (such as in albright's heriditary osteodystrophy) that risk is as high as 50%. ...Read more
Do not use if pregna: Category x drugs are contraindicated for use in pregnancy due to studies demonstrating evidence of serious fetal abnormalities in animals, humans, or both such that fetal risks clearly outweigh maternal benefit. Check out http://www. Empr. Com/drugs-contraindicated-in-pregnancy/article/125914/ for more info, including partial list. ...Read more
Laughter, of course: Sorry for the glib answer. Since there are thousands of medicines for thousands of conditions, could you be more specific in your question. Overall, I think antibiotics are one of the most amazing inventions in the history of mankind. ...Read more
Many of them: This is not an easy answer since there are many drugs categorized as unsafe. The american porphyria foundation has good resources on drug safety: http://www. Porphyriafoundation. Com/testing-and-treatment/drug-safety-in-acute-porphyria. Just because a drug may be listed as unsafe doesn't mean it's unsafe for everyone. However, it's important to use caution with any drug that is potentially unsafe. ...Read more
Yes: It is one of the chemo agents used in conjunction with Xeloda (capecitabine) (oral 5FU) or in the chemo combination with Folinic acid, 5 FU and the oxaliplatin as FOLFOX. The platinum targets DNA but in tumors the localization site is on tumor membrane where DNA localizes possibly in the form of mutated mitochondrial DNA ...Read more