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Doctor insights on: Medicine For Prochlorperazine Allergy

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Dr. John Chiu
2,638 Doctors shared insights

Allergies (Definition)

Allergies occur when your immune system is triggered by envirionmental factors it should ignore--for example, pollen in the air, or dander on a cat or dog--and creates cells to fight against them. An allergic reaction typically causes itching, congestion, or drainage, and ...Read more


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Is it common practice to prescribe compazine (prochlorperazine) for a 17 yr old for upset stomach from pollen allergies, took for a week and had extreme allergy.

Is it common practice to prescribe compazine (prochlorperazine) for a 17 yr old for upset stomach from pollen allergies, took for a week and had extreme allergy.

Nausea: Compazine (prochlorperazine) is a well known anti-nausea medicine, but one that has a lot of side effects. I personally have never had a patient with nausea caused by pollen allergies that was so bad that they needed any anti-nausea medication, but I don't know how severe this child's symptoms were. I generally try to treat the allergies first, which I think is pretty standard practice. ...Read more

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If I am allergic to compazine, (prochlorperazine) are there other drugs I should avoid?

If I am allergic to compazine, (prochlorperazine) are there other drugs I should avoid?

Some similar drugs: Prochlorperazine (compazine) is a phenothiazine type of drug. Other phenothiazine drugs include: Promethazine (phenergan), Chlorpromazine (thorazine), Fluphenazine (prolixin), trifluoperazine (stelazine), etc... A person allergic to Compazine (prochlorperazine) may choose to avoid other drugs of the same type, but it is hard to predict which similar drug he will react to. ...Read more

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If I am allergic to Compazine (prochlorperazine) (tongue swelled up 26 years ago!), is it safe to take Hydroxyzine? Always told to be aware of "zine" drugs.

They are not close: In this case, the name does NOT tell you much about the chemical structure of the drug and these two are not very similar and do NOT generally cross react at all.
Without an actual examination, I cannot give specific medical advice on your particular health, and you could have reactions to more than one drug regardless of which two drugs we choose, but these two drugs aren't closely related. ...Read more

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How are antipsychaotic drugs like compazine (prochlorperazine) used for sedation and psychosis when they cause akithesia and dystonia? I've seen it make people crazier

How are antipsychaotic drugs like compazine (prochlorperazine) used for sedation and psychosis when they cause akithesia and dystonia? I've seen it make people crazier

Antipsychotics: Every medication has side-effects, and antipsychotics are no exception. If used cautiously ; with clear indications ; close monitoring, they are for the most part safe. ...Read more

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17 yrs old was prescribed compazine (prochlorperazine) by gp had stomach ach I read that it's a anti psychotic drug effecting dopamine, does that create permanent chgs?

17 yrs old was prescribed compazine (prochlorperazine) by gp had stomach ach I read that it's a anti psychotic drug effecting dopamine, does that create permanent chgs?

Antiemetic: Used safely for yrs to alleviate nausea ; vomiting oral im ; suppository routes usually only a few doses--shouldn't cause any lasting harm. ...Read more

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Can I take antivert if I'm allergic to compazine (prochlorperazine)?

Can I take antivert if I'm allergic to compazine (prochlorperazine)?

Yes: They are in different drug classes and should not cross react. However they are not usually given for the same indication. If you are looking for a good substitute for nausea a better choice would be zofran and/ or possibly dramamine. Phenergan (promethazine) is very sedating and may not be tolerated but is also a possibility if looking for nausea solution. Antivert is acceptable. ...Read more

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If I'm allergic to compazine (prochlorperazine) can I take Dramamine?

Allergy: Please contact your primary doctor about this. If you are allergic to compazine (prochlorperazine) please stop taking it and listen to your doctor's advice.

Hope all goes well. ...Read more

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How long for 5mg of compazine (prochlorperazine) to leave system? Had for migrain cocktail, feeling restless/anxious!

Liver/kidney at work: This medication has to be metabolized in the liver, and there are both biliary and kidney elimination routes, after liver clearance. Therefore, it might take 8 hours or longer. However, side effects might clear when blood level is gradually lower. ...Read more

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Does prochlorperazine help with anxiety?

Does prochlorperazine help with anxiety?

Yes,: It can help in the short term. But side effects limit its' use over the long term. ...Read more

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Does compazine (prochlorperazine) help anxiety?

Compazine (prochlorperazine): Nope. This drug is used to help alleviate nausea. ...Read more

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Are prochlorperazine and procyclidine the same thing?

Are prochlorperazine and procyclidine the same thing?

Procyclidine/Prochlo: Prochlorperazine (Compazine) is for treating nausea/vomiting. Procyclidine (Kemadrin) is for treating side-effects of Antipsychotics. ...Read more

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Can you take atorvastatin 40mg and prochlorperazine 5mg together?

Can you take atorvastatin 40mg and prochlorperazine 5mg together?

Yes: According to Epocrates my subscription drug app. There is no interaction between these 2 drugs. However
I added your other listed drugs. There are interactions btw Norco and Tylenol; Compazine (prochlorperazine) and Norco. Contact your pharmacist and Doctor to discuss the risks benefits of taking all of these drugs together at once. ...Read more

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What happens if you take percocet with compazine (prochlorperazine)?

Sedation and more: These medications should only be taken together if specifically directed by your physician. The combination will be more sedating and constipating. There are reports of low blood pressure.
Only take these if your physician directed you to do so and follow up with her/him if you have any issues. ...Read more

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How long after taking 10mg of metoprolol can I take 10mg of prochlorperazine?

How long after taking 10mg of metoprolol can I take 10mg of prochlorperazine?

Drug interaction: The two drugs that you mention are noted to have a drug interaction in that they might cause your blood pressure to drop even further. All drug interactions are not necessarily bad and they will not necessarily happen in you. It has been noted. ...Read more

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Likelihood of developing more serious effects from compazine (prochlorperazine) (NMS, kidney function etc) from a sing 5 mg dose?

Very unlikely: Compazine (prochlorperazine) is a very routinely used medication with an overall safe adverse effect profile. It would be incredibly rare to see more serious adverse effects like NMS from a single low dose of 5 mg. ...Read more

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Which causes more drowsiness - compazine (prochlorperazine) or zofran?

Which causes more drowsiness - compazine (prochlorperazine) or zofran?

Compazine (prochlorperazine) does...: Ondansetron (zofran), a powerful anti-nausea drug, is a serotonin 5-ht3 receptor antagonist. It blocks these "receptors" linked to the crtz. The "vomiting center" located in our brains. Compared to compazine, (prochlorperazine) a piperazine phenothiazine linked to other brain receptors (d2), it causes very little sedation. Both are used to decrease nausea and vomiting after surgery. ...Read more

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Is tounge swelling or protrusion a common side effect of compazine (prochlorperazine)?

Is tounge swelling or protrusion a common side effect of compazine (prochlorperazine)?

Prognosis: It is a common side effect but other possibilities can't be rules out. ...Read more

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I had sezures taking Compazine (prochlorperazine) and Thorazine. Can I take 10 mg of cyclobenzaprine safely? Thank you

I had sezures taking Compazine (prochlorperazine) and Thorazine. Can I take 10 mg of cyclobenzaprine safely? Thank you

2 issues: First, you are risk to have seizure activity secondary to a variety of triggers and should be taking a daily anti-epileptic drug. Second, cyclobenzaprine is very unlikely to cause seizure activity, but nonetheless, start your seizure medicine first. Have a neurologist evaluate all of this. ...Read more

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Is there a cocktail of meds that break status migrainousos particularly well? Read iv compazine (prochlorperazine) and iv dihydroergotamine.

Good combination: Or adding Toradol to the cocktail. Alternatively for status, a small amount of steroid and or narcotic like Demerol (meperidine hydrochloride) or MS. ...Read more

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Took 0.5mg xanax at 6pm yesterday. How long should I wait to safely take my prescription of Compazine (prochlorperazine) today? (It's 3pm now)

Took 0.5mg xanax at 6pm yesterday. How long should I wait to safely take my prescription of Compazine (prochlorperazine) today? (It's 3pm now)

No wait.: Alprazolam has a short half-life and a short duration of action; it doesn't dangerously interact with Compazine (prochlorperazine). Why not ask your prescriber directly? ...Read more

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Why are antipsychaotics like compazine (prochlorperazine) often termed "major tranquilizers" when they often cause akithesia and anxiety and do the opposite of tranquil?

Good point: In psychiatry, we call those medications antipsychotics, because they are usually used to treat psychotic symptoms. We don't use the term tranquilizer, because it is misleading.
As far as your question is concerned, the side effects you mention are unintended, so they are not part of the intended use. As for anxiety, I'm not familiar with the antipsychotics causing anxiety. ...Read more

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Is is ok to drink alcohol whilst taking prochlorperazine?

Is is ok to drink alcohol whilst taking prochlorperazine?

Alcohol and Nausea: Nope. Alcohol is very hard on the stomach. Taking a medication to calm the stomach while drinking alcohol that is harsh on the stomach makes no sense. ...Read more

Dr. Janice Alexander
52 Doctors shared insights

Prochlorperazine (Definition)

Prochlorperazine is an inotrope which is a kind of heart ...Read more


Compazine (Definition)

Prochlorperazine is an inotrope which is a kind of heart ...Read more