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Doctor insights on: Medicine For Primary Ovarian Insufficiency

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What are the tests for primary ovarian insufficiency?

What are the tests for primary ovarian insufficiency?

Many tests, see REI: Reproductive endocrinology md will confirm poi - pregnancy test, fsh, lh, estradiol, amh, thyroid and prolactin tests, pelvic ultrasound. Test for genetic causes: karyotype looking for turner's syndrome, fragile x premutation testing, fish test for sry (y-chromosome material). Test adrenal antibodies which cause addison's disease. Screen for diabetes, thyroid antibodies, and parathyroid disease. ...Read more

Dr. Michael Opsahl
28 Doctors shared insights

Ovarian Insufficiency (Definition)

"Primary ovarian insufficiency describes a spectrum of declining ovarian functions and reduced fecundity due premature decrease in follicle number, an increase in follicle destruction or poor response to gonadotropins".This abnormal "Hypoestrogenic state" increases risks of vasomotor symptoms, urogenital atrophy, osteoporosis, fractures, cardiovascular diseases and other ...Read more


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What are the symptoms associated with primary ovarian insufficiency?

What are the symptoms associated with primary ovarian insufficiency?

Irregular/ no period: Irregular cycles or no periods, especially in a woman who was regular before, is a common sign. However there are many other causes of irregular cycles that we need to exclude. Hot flashes, vaginal dryness, or mood changes may occur, particularly if the woman's periods are stopped. Some women with primary ovarian insufficiency still have regular periods but see md for difficulty getting pregnant. ...Read more

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What is the definition or description of: Primary ovarian insufficiency?

What is the definition or description of: Primary ovarian insufficiency?

Early failure: Premature ovarian failure is a loss of normal function of your ovaries before age 40. If your ovaries fail, they don't produce normal amounts of the hormone estrogen or release eggs regularly. ...Read more

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Are there certain things that make getting primary ovarian insufficiency more likely?

Are there certain things that make getting primary ovarian insufficiency more likely?

Early ovarian failur: Chemotherapy, ovarian surgery, genetics, exposure to radiation would be the most common antecedants. ...Read more

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What is the treatment for primary ovarian insufficiency?

What is the treatment for primary ovarian insufficiency?

Trying to conceive?: If not trying to conceive: bone density scan, calcium, vitamin d, and hormone replacement with estrogen and progestin. We look for and treat any adrenal insufficiency. If you're trying to conceive, 5-10% of women with poi will get pregnant on their own after diagnosis, but if you truly have poi we don't have good fertility treatments using your own eggs. Egg donation or embryo donation are best. ...Read more

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Is it common for primary ovarian insufficiency to develop postpartum?

Is it common for primary ovarian insufficiency to develop postpartum?

Early menopause: Premature ovarian failure can occur at any age, but it is unusual immediately following pregnancy. Regular menses suggest ovulation and a healthy ovary, but there are many causes of lack of menses after having a baby. Included considerations are breastfeeding, polycystic ovaries (estrogen is produced, but no ovulation), another pregnancy! Pituitary failure (sheehan's syndrome) is a rare cause. ...Read more

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With primary ovarian insufficiency and not taking hrt, is it possible for a woman to get an occasional period?

With primary ovarian insufficiency and not taking hrt, is it possible for a woman to get an occasional period?

Kinda: If you have little to no estrogen from your ovaries you should not bleed at all. But if you have some in your diet or are overweight you may have bleeding so talk to your obgyn or endocrinologist. ...Read more

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Was planning to see classmates at upcoming 20th reunion. Now I am hearing my best friend has ovarian insufficiency. What is that?

Premature menopause: Ovarian insufficiency is another way of saying someone is going through menopause. There can be various causes of why someone might go through this prematurely. This can be treated with supplemental hormones and should not keep your friend from attending the reunion. ...Read more

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What are the symptoms of ovarian insufficiency?

What are the symptoms of ovarian insufficiency?

Irregular/ no period: Irregular cycles or no periods, especially in a woman who was regular before, is a common sign. However there are many other causes of irregular cycles that we need to exclude. Hot flashes, vaginal dryness, or mood changes may occur, particularly if the woman's periods are stopped. Some women with primary ovarian insufficiency still have regular periods but see md for difficulty getting pregnant. ...Read more

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What is the definition or description of: Ovarian insufficiency?

What is the definition or description of: Ovarian insufficiency?

Spectrum of disorder: "Primary ovarian insufficiency describes a spectrum of declining ovarian functions and reduced fecundity due premature decrease in follicle number, an increase in follicle destruction or poor response to gonadotropins".This abnormal "Hypoestrogenic state" increases risks of vasomotor symptoms, urogenital atrophy, osteoporosis, fractures, cardiovascular diseases and other issues if left untreated ...Read more

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What is the treatment for ovarian insufficiency?

What is the treatment for ovarian insufficiency?

Trying to conceive?: If not trying to conceive: bone density scan, calcium, vitamin d, and hormone replacement with estrogen and progestin. We look for and treat any adrenal insufficiency. If you're trying to conceive, 5-10% of women with poi will get pregnant on their own after diagnosis, but if you truly have poi we don't have good fertility treatments using your own eggs. Egg donation or embryo donation are best. ...Read more

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Is there something wrong with ovaries or hormone system if I have ovarian insufficiency?

Is there something wrong with ovaries or hormone system if I have ovarian insufficiency?

EARLY menopause: Ovarian failure or 'insufficiency' is a really another name for menopause (which may be premature if <40 yo). Normally the pituitary gland (in the brain) sends 2 hormone messengers FSH & lh to 'tell' the ovary to make estrogen/'female' hormones. When the ovary 'fails' =estrogen levels drop and fsh/lh levels rise confirming ovarian 'insufficiency'. Treatment with 'hormones' is optional. ...Read more

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Normal paps, neg. HPV, slight burning during and spotting after sex. Have primary ovarian insuffciency and vag. Dryness. Worried about cancer. Likely?

Normal paps, neg. HPV, slight burning during and spotting after sex. Have primary ovarian insuffciency and vag. Dryness. Worried about cancer. Likely?

Vaginal irritation: Due to your ovarian insufficiency, your estrogen levels are likely low, leading to the vaginal dryness. This dryness is likely the cause of the burning during intercourse and the spotting after. There are excellent estrogen creams that can be used vaginally to reduce dryness. Lubricants may also be helpful, but long term the condition will likely respond better to the estrogen cream. ...Read more

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Has anyone seen a patient with adrenal insufficiency, intermittent ovarian failure, intermittent glucose intolerance, and thyroid values in normal range? Perhaps also with a pituitary tumor?

Has anyone seen a patient with adrenal insufficiency, intermittent ovarian failure, intermittent glucose intolerance, and thyroid values in normal range? Perhaps also with a pituitary tumor?

Pituitary tumors: You need an endocrinologist to sort this out. A big pituitary tumor (>10 mm) can wipe out other hormones; you could lose some (eg reproductive) but not others. Typically the last to go from a pituitary insult is TSH and acth (thyroid and adrenal), but odd things can occur. A micro tumor does not usually damage the rest of the pituitary, but may produce excess hormone (eg. Prolactin, acth). ...Read more

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Could I treat premature ovarian failure with traditional chinese medicine?

Could I treat premature ovarian failure with traditional chinese medicine?

Yes: You can try. There is certainly no harm in trying as long as the medicine you try is safe and you are monitored. But there is no evidence that any form of therapy works well to reverse the ovarian failure. Treating symptoms is different. ...Read more

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Are there new drugs which could improve management of ovarian cancer patients?

Are there new drugs which could improve management of ovarian cancer patients?

Much too broad a??: Cancer is very complicated and it is evaluated for each patient differently. Speak with an oncologist. ...Read more

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Have I got primary ovarian failure?

Have I got primary ovarian failure?

Are you kidding?: How would we know? Your question is six words long. It has no symptoms or history that would be the basis of your asking us this question. ...Read more

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What's the primary ovarian cyst symptoms?

What's the primary ovarian cyst symptoms?

Most women have none: Ovarian cysts are common and occur monthly in cycling females. Some women will have some pain, especially if a cyst ruptures and bleeds. Most cysts go away spontaneously. Persistent cysts may be felt on exam or may cause some discomfort such as bloating, pain or if large enough, bladder or bowel symptoms. ...Read more

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Fertility: thoughts on frenchscientists discoving link btw use of ovarian stim drugs to a 2.6 fold increase in acute lymphoma inchildren. Chlomid ok?

Fertility: thoughts on frenchscientists discoving link btw use of ovarian stim drugs to a 2.6 fold increase in acute lymphoma inchildren. Chlomid ok?

Clomid (clomiphene) risk: As with everything in medicine, time will tell, more research, etc also, if Clomid (clomiphene) is the way a couple can have a baby the benefit versus risk of other alternatives must be considered as well as costs. Clomid (clomiphene) is one of the most affordable means to stimulate ovulation. ...Read more

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Is a 6cm by 7cm ovarian simple cyst classified as a large cyst? Will a cyst that size require surgery if its getting bigger despite taking medicine

Is a 6cm by 7cm ovarian simple cyst classified as a large cyst? Will a cyst that size require surgery if its getting bigger despite taking medicine

Maybe: We usually consider cysts to be large if they are greater than 8 cm but that does vary some from institution to institution (some set the line at 6 cm). Simple cysts are almost always benign and can be observed unless they are symptomatic. If they are enlarging, however, surgery may become necessary. Hope that helps. ...Read more

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How treatable is ovarian cancer with today's medicine?

How treatable is ovarian cancer with today's medicine?

Fairly well: We have modestly good treatment for ovarian cancer. If caught early it is curable in half to two thirds of cases. But commonly it presents as stage 3-4 disease where the cure rate drops to 25-30%. Yet the available chemotherapy can buy several years of good life when patient is treated by a specialist (gynecologic oncologist). Good luck. ...Read more

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Can clomiphen or Clomid (clomiphene) used in primary ovarian failure?

Can clomiphen or Clomid (clomiphene) used in primary ovarian failure?

No Clomid (clomiphene) cant be: Hello
Clomid (clomiphene) (clomiphen) cannot be used in primary ovarian failure. In primary ovarian failure the ovaries do not produce estrogen to cause ovulation (egg release). Clomid (clomiphene) (clomiphen) works by preventing estrogen from being turned off in the body. If someone does not produce estrogen in the first place than clomid (clomiphene) cannot work. But primary ovarian failure requires a doctor to determine if pt has it ...Read more

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Is there an alternative medicine that is helpful for polycystic ovarian syndrome?

Is there an alternative medicine that is helpful for polycystic ovarian syndrome?

None proven to work: Nothing with any good evidence that it works including herbal supplements like vitex agnus castus, chinese herbal medicine or acupuncture. One study of real vs. Sham acupuncture bit. Ly/pmorbf. ...Read more

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Why won't my doctor perctibe me pain medicine for my ovarian cyst? It is very painful.

Why won't my doctor perctibe me pain medicine for my ovarian cyst? It is very painful.

Local problem: We cannot possibly know that answer on this international app. Please ask them. ...Read more

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What fertility drugs can you take with ovarian cyst?

What fertility drugs can you take with ovarian cyst?

Depends...: The answer depends on the size of the cyst and other factors. You should discuss this with your Ob/Gyn or fertility specialist. Best wishes! ...Read more

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Do fertility drugs increase your risk of developing ovarian cancer?

Do fertility drugs increase your risk of developing ovarian cancer?

Minimal: If there is a risk, is with Clomid (clomiphene) after 12 months of use and the risk is minimal. The greatest risk is infertility itself and not the medications. In the grand majority of patients there is no reason to use Clomid (clomiphene) for 12 months. The treatment is usually changed if the patient has not conceived after 4-6 cycles. ...Read more

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I've been taking risperdal for 10 months, but I have developed an ovarian cyst. Should I ask for a different drug?

I've been taking risperdal for 10 months, but I have developed an ovarian cyst. Should I ask for a different drug?

Discuss: Rather than ask for a different drug as the first step, I would discuss with your prescribing doc your concern about taking Risperdal given that you have an ovarian cyst. Your benefit from Risperdal will need to be weighed against the potential impact on your cyst. ...Read more

Dr. David Frankfurter
116 Doctors shared insights

Primary Ovarian Insufficiency (Definition)

Premature ovarian failure is a loss of normal function of your ovaries before age 40. If your ovaries fail, they don't produce normal amounts of the hormone estrogen ...Read more