Doctor insights on:
Medicine For Panhypopituitarism
Maybe (see comment): There is a form of panhypopituitarism called sheehan's syndrome, that can occur after pregnancy. This is due to the pituitary enlarging and needing more blood blow during pregnancy than at other times. If delivery is complicated by hemorrhage, and the blood pressure drops rapidly, there may be too little blood flow to the pituitary, resulting in death of the cells & panhypopituitarism. ...Read more
Yes: This is one thing you definitely should not ignore. If you ignored it and you don't die, then you didn't have panhypopituitarism. Among other things, the pituitary control your adrenal and thyroid glands. Without adrenal and thyroid hormones, one will be severely sick and will most likely not live...Don't ignore this. It is a difficult diagnosis to make. ...Read more
Subtle: In an adult, just feeling unwell, loss of sexual function / failure of lactation, "the blahs" -- the symptoms are subtle enough that many of these people end up being sent for mental health checks before a clever physician finally notices the lost pituitary gland. If a mass, headaches & visual field cuts. Have a high index of suspicion, and good luck. ...Read more
Rare: Hi. Genetic causes of panhypopituitarism are very rare, and several involved genes have been described. Depending on the gene and its product's mechanism of action, panhypopit. Can be expressed by getting only 1 mutant allele (autosomal dominant), by getting 2 mutant alleles (autosomal recessive), or X-chromosome linked, where generally only males get the panhypopit (females are carriers. Complex. ...Read more
Fatigue, no period: Due to a lack of stimulation to the thyroid and adrenals, untreated hypopituitarism causes fatigue. For women, loss of periods is usually the first symptom. ...Read more
Panhypopituitarism: Panhypopituitarism = condition with lack of or decreased production of anterior pituitary hormones. ...Read more
Multiple replacement: True panhypopituitarism generally requires replacement with multiple hormones and may even require tx for excess urination due to diabetes insipidus. Severe panhypopit is often a medical emergency. Pay careful attention to the advice of your endocrinologist. Also, find out the cause of the deficiency because other tx (such as surgery) may be indicated. ...Read more
Not true: They can have children. Steps to take 1. What is the cause of panhypopituitarism? Is it genetic 2. Are there sperm in ejaculate (detected by semen analysis) 3. If few sperm are found consideration is given to freeze them 4. If no sperm then consideration for treatment with injectable medications to increase sperm production. 5. Sperm are used for ivf and icsi. ...Read more
Coordinate care: With your medical team, primary care, specialists, psychologist and psychiatrist, it is especially important for all doctors to coordinate medication treatments. As with any chronic illness, there is emotional fallout. Having a psychotherapist to speak to about your anxiety will help you manage the illness as well as possible. ...Read more
Endocrinologist: You should seek out an endocrinologist. If you go to the website of the american association of clinical endocrinologists there is a "find an endocrinolgist" section that will refer you to someone in your area. ...Read more
I have panhypopituitarism and I am cortisol dependant. Is there a diet pill out there that would be safe for me to use?
My son is a craniopharyngioma patient, total resection 6/11 (now panhypopituitarism). Oncologist earlier this week, ldh is 1001. What does this mean?
Not good news.:
Used in risk stratification system,
four pretreatment laboratory findings were independent risk factors for tls (tumor lysis syndrome) serum ldh above laboratory normal values, serum creatinine ≥1.4 mg/dl (124 micromol/l), pretreatment serum uric acid >7.5 mg/dl (446 micromol/l), and white blood cell (WBC) count ≥25, 000/microl. ...Read more
At age 8 I was dx'd with panhypopituitarism, multiple pineal cysts, and a mild chiari malformation. Now, my doctor suspects I have endometriosis or pcos. Could all these conditions be related and how?
With proper treatmen: The pituitary gland is small, but amazingly complex in term of its job--it regulates reproductive, metabolism, and growth processes. The hormones are easily replaced, but this requires a life-time commitment from you, under guidance of your docs. And yes, u can get pregnant and do well once you are regulated and should be monitored regularly by your physicians. I wish you the best of luck. ...Read more
Do not use if pregna: Category x drugs are contraindicated for use in pregnancy due to studies demonstrating evidence of serious fetal abnormalities in animals, humans, or both such that fetal risks clearly outweigh maternal benefit. Check out http://www. Empr. Com/drugs-contraindicated-in-pregnancy/article/125914/ for more info, including partial list. ...Read more
Laughter, of course: Sorry for the glib answer. Since there are thousands of medicines for thousands of conditions, could you be more specific in your question. Overall, I think antibiotics are one of the most amazing inventions in the history of mankind. ...Read more
Many of them: This is not an easy answer since there are many drugs categorized as unsafe. The american porphyria foundation has good resources on drug safety: http://www. Porphyriafoundation. Com/testing-and-treatment/drug-safety-in-acute-porphyria. Just because a drug may be listed as unsafe doesn't mean it's unsafe for everyone. However, it's important to use caution with any drug that is potentially unsafe. ...Read more
Yes: It is one of the chemo agents used in conjunction with Xeloda (capecitabine) (oral 5FU) or in the chemo combination with Folinic acid, 5 FU and the oxaliplatin as FOLFOX. The platinum targets DNA but in tumors the localization site is on tumor membrane where DNA localizes possibly in the form of mutated mitochondrial DNA ...Read more