Doctor insights on:
Medicine For Pagets Disease Of Bone
Bone is a living growing tissue made mostly of collagen (protein that provides soft framework) & the mineral calcium phosphate that adds strength & hardens the framework. Two types of bone are found in the body; cortical (dense compact outer layer) & trabecular (makes up inner layer, ...Read more
Not very much to:
Start. Most people who have paget's disease of bone experience no symptoms. When symptoms do occur, the most common complaint is bone pain.
Pelvis. Paget's disease of bone in the pelvis can cause hip pain.Skull. An overgrowth of bone in the skull can cause hearing loss or headaches.
And others see the link below. ...Read more
The answer: Is too extensive for 400 words or less, but try this link: http://www. Orthochirurg. Com/resources/journals/JAAOS/Volume3/V3N6A4.pdf ...Read more
No: Paget's is not caused by infectious agents including viruses. ...Read more
No: I do not believe the two are interconnected. ...Read more
No: Paget's disease is a disorder of abnormal bone remodeling. We all lose and build none everyday. In paget's, there's more building than losing, but in an abnormal structure, which makes the bone unstable and prone to breaking. There is often a lot of blood flow to the areas involved and so it can be red and hot. ...Read more
Yes: Actonel (risedronate) is also commonly used.Get a more detailed answer ›
Giant: Cell tumor is a rare complication of paget's disease of bone. ...Read more
None: While called an endocrine disorder, to my knowledge, there is no specific organ/gland damage. Any pathologist can to weigh in? ...Read more
Pagets disease: Pagets disease of the bone has nothing to do with Paget's disease of the breast. ...Read more
Bone disorder: Paget' disease is a localized disorder of bone remodeling that involves excessive bone resorption, followed by increased bone formation. This overactivity followed by compensatory bone cell activity leads to a structurally disorganized mass of bone (woven bone), which is weaker, larger, more vascular, and more susceptible to fracture. It can be seen on x-rays, and can be a cause for bone pain. ...Read more
Benign usually: Bone enlarges, can be painful, rarely can lead to malignancy. ...Read more
Depends on age: SMalignant bone tumors begin in pre teens as PNET lesions ie Ewings sarcoma. This progress with age to osteogenic Sa. In older teens we see osteogenic sarcoma. Older people get enlarging lesions such as Pagets disease which converts to sarcoma. Cartilagenous tumors can be congenital or isolated as parostoeal chondrosarcomas. With many epithelial malgiancies tumors can spread to bone. ...Read more
No short answer: There are literally hundreds of primary bone or systemic (whole body) disorders that can affect bone formation, metabolism, maintenance. There are just as many benign and malignant tumors that can arise in or affect bone. Expertise in bone diseases crosses many specialties as well quite a few textbooks. ...Read more
Yes: Usually systemic.Get a more detailed answer ›
What is the % of getting Paget's disease of the bone if there is a family history and have symptoms that could fit?
Cannot estimate: No one even knows what percentage of older folks actually have some paget's lesions, since the disease is usually subclinical. If older folks with an unexplained elevation of alkaline phosphatase are assumed to have paget's, it's maybe 10%. The key is that paget's can be managed nowadays and of course it's largely hereditary. Let your physician know of the family history. ...Read more
There are so many:
Achondroplasia (dwarf), osteogenesis imperfecta (brittle bones, fragilitas ossium)
osteopetrosis (marble bone disease, osteosclerosis) hereditary multiple exotosis (osteochondromatosis) osteochondromatosis of radius and ulna.
Osteochondromatosis of humerus. Cartilage-capped solitary osteochondroma of rib. Enchondromatosis (ollier's disease). ...Read more
Varies: There are multiple disease processes that can involve the bone. Many are metabolic and affect the rate and manner on which bone is formed; osteoporosis and osteomalacia are two examples. Endocrinologists are among the specialists that treat many forms of bone diseases if you need evaluation, as do rheumatologist and some orthopedic surgeons. ...Read more
Vinegar can cause osteoporosis by inhibiting calcium synthesis in the bones. Drink milk!
however, naturally fermented apple vinegar (cider) has healing properties associated with beta-carotene, pectins, potassium, sodium, magnesium, calcium, phosphorous, chlorine, sulphur, iron, and fluorine. ...Read more
Any: Any bone can be affected, but most commonly, the skull and the long bones of the legs and arms. ...Read more