Doctor insights on:
Medicine For Osteonecrosis
Nothing I'm aware of: Osteonecrosis is a poorly understood process. It can be caused by steroids, trauma, vascular insult, alcohol, or be idiopathic. Once it has started, I am not aware of any medications or alternative medicines which arrest the process. There has been some suggestion that bisphosphonates can arrest the process in the case of idiopathic osteonecrosis (perthes), but this is still investigational. ...Read more
Aseptic necrosis is also called osteonecrosis, avascular necrosis (AVN), or ischemic bone necrosis. It is a condition that occurs when there is diminished blood to the bone. An interruption to the blood supply causes bone to die. If the environment is not altered or improved, the involved bone may eventually collapse and ...Read more
I took zometa IV 7yrs ago. Now I have osteoporosis & was prescribed an oral similar drugs. Will this cause osteonecrosis of jaw? My tooth hurts!
See dentist: You can have dental treatment while you are taking medications for osteoporosis. Dental care is extremely important and you want to save your teeth if possible. Your dentist will discuss the very low risk of osteonecrosis after extractions with you. Try to treat the tooth rather than remove it. ...Read more
See below: First off weight bearing and with a special boot for several weeks; some respond but not a many. Second a core of bone to decompress. This works in most cases. Third, if not helped by the above a small number of people need an arthrodesis. You should be under the care of a board certified Orthopedic Surgeon. ...Read more
Pain: Osteonecrosis causes pain and stiffness. It is most commonly found in the hip followed by the knee. See an orthopedic surgeon early, as some procedures can be used to arrest progression early in the disease process (not uniformly successful). After structural damage and mechanical malalignment have occured, arthroplasty may be necessary. ...Read more
osteonecrosis or avascular necrosis (avn), is essentially death of bone. It can happen from trauma, medications, as well as many other causes.
The specific bone that is affected & how severe the osteonecrosis is makes a big difference. Bones like the femoral head (at hip) or the talus can cause severe impairment. Avn of the humerus at the shoulder is sometimes well tolerated. ...Read more
Pain, Swelling: Erythema (redness). Some patients may also present with complaints of numbness and non-healing extraction site. ...Read more
Osteonecrosis means-: -death of bone. This is due 2 loss of blood supply 2 a certain bone part. Common after some injuries such as fractured navicular in the wrist, dislocation of the hip. Some R due 2 drugs, especially steroids, also alcoholism, in these cases it's usually the hip or shoulder. ...Read more
Cavity and neuralgia: Neuralgia-inducing cavitational osteonecrosis, refers to presence of cavitations in jaw bones (mandible and/or maxilla) in conjunction with chronic facial neuralgia. The concept implies direct and causal relationship between the bone pathology (cavitations) and pain itself. Pain in this setting is commonly described as atypical facial neuralgia and is chronic in nature. ...Read more
A drug side-effect: The drugs for osteoporosis and metastatic bone cancer called bisphosphonates (includes fosamax, actonel, boniva, reclast, (zoledronic acid) zometa, aredia) are associated with a side-effect where part of the bone of the jaw dies, the gum sloughs off, and bone shows where the gum was lost. It is treatable but not always curable. It has also been found with bevicizumab, an anti-cancer drug, and after jaw radiation. ...Read more
Possibly: Osteonecrosis or avascular necrosis (avn), theorized to be due to loss of blood supply to the bone for whatever reason. So technically yes the bone is ischemic and thus dies off. Sometimes there is a known cause, but oft times none can be found. Associated with blood dyscrasias such as sickle cell disease, steroid use, trauma, chronic alcoholism. ...Read more
X-rays: Ostenecrosis - death of bone can be visualized on an x-ray. Biopsy is another mechanism if unsure of the x-ray finding. ...Read more
Osteonecrosis of the knee is a common source of debilitating knee pain.
It generally affects the medial femoral condyle in women >55yrs old.
Secondary osteonecrosis of the knee is related to corticosteriod use, alcohol abuse, sickle cell anemia, systemic lupus erythematosus. Secondary osteonecrosis is generally in patients <45 years old and is often bilateral. ...Read more
Minor & Severe:
Treatment should be tailored to the individual patient according to the etiological factors involved and the severity of the disease process in minor cases conservative treatment usually give good result
in cases of advanced that are not bisphosphonates related has shown that surgically removing the damaged marrow usually by curettage and decortication will eliminate the problem & pain in 74%. ...Read more
Osteonecrosis: This most often is painful but there are times where there is not much pain. You cannot use this as diagnostic symptom. You need to have your dentist evaluate things to make sure what is going on. ...Read more
Pain swellilng: Pain swelling of the jaw, sometimes exposed bone. Usually after tooth extraction. Not always. See oral surgeon to sort things out. ...Read more
Nonoperative treatment usually results in a poor prognosis.
Core decompression core decompression is currently the most common procedure in the early stages of osteonecrosis of the femoral head. Based on harris hip scores operative treatment was successful in approximately 70% of hips with ficat stage I ii or iii osteonecrosis comparing to 20% of nonoperative management of early osteonecrosis. ...Read more
Yes: I have not personally, but this is a problem that has been written about extensively. There is a direct causal relationship between the two. ...Read more
I have both tarlov cysts & osteonecrosis. Found out about them at the same time. Can the cysts cause the osteonecrosis?
Not likely: Tarlov cysts (perineural cysts) are benign sometimes enlarging lesions in the lumbosacral spine that are usually found incidentally by xray or MRI. They can cause back pain, nerve pain and leg weakness. Some require surgical treatment if they are pushing on a nerve. They are not causally related to osteonecrosis. ...Read more
Shoulder replacement: The stotal shoulder is a good procedure. ...Read more