Doctor insights on:
Medicine For Non Small Cell Lung Cancer
Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more
What kind of results have been found using the drug xalkori or crizotinib for non small cell lung cancer?
80% in some patients: In patients whose tumor has a specific mutation that makes it sensitive to the drug (alk translocation) the response rate is about 80%. That is, the tumors in 80% of these patients shrink or at least stop growing. ...Read more
Mom was diagnosed with stage 4 lung cancer in 6/12. They are unsure if it is small cell /non small cell. 1st chemo drug did nothing. Life expectancy?
Not enough space: Let's see: most common category of lung cancer, often but not always tobacco related, treated with surgery if possible but radiation and chemo are often used as well. I suggest you visit the national cancer institute website. It's has good info regarding all kinds of cancers. ...Read more
Nsclc: First of all, a biopsy will need to be done to the lung mass/nodule not only to establish diagnosis but also to find the histology and genetic profile of the cancer. Then, complete staging work-up with pet/ ct scan need to be done to stage the cancer. The treatment will depend on the histology/molecular-genetic mutation status, stage, as well as overall condition and preference of a patient. ...Read more
5yr suvival bystage:
Ia = 49%
ib = 45%
iia = 30%
iib = 31%
iiia = 14%
iiib = 5%
iv = 1%
http://www. Cancer. Org/cancer/lungcancer-non-smallcell/detailedguide/non-small-cell-lung-cancer-survival-rates. ...Read more
One type of lung:
Cancer. It is not easy to explain. There are multiple subtypes within in this type. These are due to smoking and tend to spread locally as compared to early spread through blood for small cell cancer. See this site for more info.
http://www. Cancer. Gov/cancertopics/pdq/treatment/non-small-cell-lung/patient/page1. ...Read more
It depends;: Unfortunately lung cancer is usually diagnosed in more advanced stages because it can be silent. Depending on the region it involves, symptoms could varry from cough, weight loss, shortness of breath, coughing up blood, affecting voice quality. If cancer is found incidentally in early stages (patient not symptomatic and cancer found incidentally), the cure rate can be excellent. ...Read more
The stage and others: Will depend on the stage and other prognostic factors. In general, the 5 year overall survival for stage 1 is 60-80%., stage 2 is 40-50%; stage 3 is 10-23%, and stage 4 is less than 10%. These however are the statistics obtained when using regular cytotoxic chemotherapy. With more personalized and more targetted therapy-we are hoping the number will improve. ...Read more
Not good: Stage 3b non-small-cell-lung cancer is a very heterogeneous group of patients and as such there is no unanimous hard data on survival, unlike the earlier stages. Some may benefit from chemo- and radiation therapy to shrink the tumor and be resected. My advice is to go to the most renowned lung cancer specialist that is available to you and hope for the best. ...Read more
Depends on Stage: The answer to that question depends greatly on how advanced the cancer is when it is diagnosed. That, in turn, depends on how big the tumor is, where it is located, whether it has spread locally or all over the body. Generally, the earlier you catch the cancer, the longer the survival is. That is not a 100% "take it to the bank" rule, but it is a general pattern. A number of tests find out stage. ...Read more
Depends: That depends on where the tumor is: if it is spread to a vital organ, it will causes symptoms there, such as a headache if it is in the brain. If the tumor presses on the airway, it can block that part of the lung and cause pneumonia. If it blocks a blood vessel, it can cause problems with blood flow, etc. So, it depends on where it is. ...Read more
Depends on the stage: Once diagnosed you will need to be staged to evaluate for resection. In general patients with early stage lung cancer (i or ii), who are healthy enough, should be treated with surgery to remove the cancer. In the more advanced stages (iii or iv), surgery by itself is usually not curative, and other treatments like chemotherapy and radiation therapy are required. ...Read more
Bipsy and imaging: The key to diadnosis is the biopsy. This can help determine the subtype which will help guide the course of treatment. Beyond that, the imaging with ct, ct/pet, and MRI will help determine the stage of the cancer. The combination of the stage and the subtype of the cancer will help with treatment decisions as well as prognosis. ...Read more
Everything: Small cell lung cancer is almost completely different than non small cell- the only thing the same is that it is located on the lung and may give the same symptoms. They are different in molecular biology level, they look and behave differently. Small cell behaves more agressive- like systemic disease even from the first presentation; have different treatment and prognosis. D/w your oncologist. ...Read more
Not often but happen: Many of the cases of lung cancer in non-smokers, whether small cell or other - squamous cell and adenocarcinoma - are in people exposed to high levels of second-hand smoke, as well as other pollutants, including toxic industrial exposures. Asbestos exposure is a cause of another kind of lung cancer- mesothelioma - which can happen with industrial or home exposure (old insulation). ...Read more
Different cell types: Lsmall cell cancer of the ung is a neuroendocrine tumor responding to chemo such as the adriamycins (doxorubicin). Non small cell cancer represents the adenocarcinomas and squamous cell cancers requiring a different groujp of drugs that usually include the platinums and the newer monoclonal antibodies. ...Read more
Friend of mine who is 48 was dx with non small cell lung cancer stage 2a what is the prognosis. Any chance of cure?
Are p63 and ttf1 used to distinguish small cell lung cancer from non small cell lung cancer? Or are they used for more specific distinctions?
Often cures: Surgery is the standard of care for stage I and ii lung cancer in the physically fit patient, and should be considered as an option in many patients with stage iiia. Often can be done minimally invasively thorascopically or with a robot. Recovery varies with the level of invasiveness. Lung surgery has best outcomes by a board certified thoracic surgeon. ...Read more
Robot or VATS: Optimal lung cancer surgery, in appropriate candidates, is anatomic lobectomy (part of lung) or pneumonectomy (whole lung). Complete lymph node sample or dissection is integral part of case. Traditional centers use thoracotomy as primary approach. Modern minimally invasive approaches include vats and robotic techniques. Optimal lung cancer treatment is by comprehensive multidisciplinary approach. ...Read more
Possible: 30-40% at 5 years depending on cell type, location. ...Read more
Deoxygenated blood enters the lungs from the right side of the heart and travels to the lungs. When you inspire, oxygen flows into the lungs, transverses the capilliares and attaches to hemoglobin down a gradient. At the same time, co2 diffuses into the capilaries and is expelled with exhalation. Oxygen rich blood then flows to the left side of the heart and into the ...Read more