Doctor insights on:
Medicine For Neuromuscular Junction Diseases
Disorder related: There are many neuromuscular diseses, treatment is specific to the disorder when possible. In myasthenia gravis treatment may include surgery, immunospression and medication to improve n-m transmission. There are inflammatory muscle disorders that require prolonged immunosupression. There are nerve and muscle disorders associated with vitamin deficiencies. In others we can only treat symptoms. ...Read more
The term neuromuscul: The term neuromuscular disorder is a broad term that encompasses many different conditions. In general there is a neurologic problem that negatively influences muscle and motor function. There are usually symptoms of weakness and or impaired coordination. In order to make a correct diagnosis it is important to be evaluated by a specialist like a neurologist who can perform an appropriate eval. ...Read more
There are many: There is lots of information on the Web about this subject. You might start here: http://www. Nlm. Nih. Gov/medlineplus/neuromusculardisorders. Html. For more depth, there are comprehensive books on the subject, e.g. "Neuromuscular Disorders" by Amato and Russell. At 775 pp it's a good introductory text. ...Read more
Raynaud's diusease: When you use the term "vascular hyperreactivity", the closest problem that fills the description is Raynaud's phenomenon. This is most common a "stand-alone" problem that occurs with cold. It can also be a feature of connective tissue diseases such a scleroderma and related disorders. ...Read more
Specifics needed: Some neuromuscular disorders, for example myotonic dystrophy, may cause heart problems such as abnormal heart rhythm. Some neuromuscular disorders do not have any associated heart problems. So it depends on the specific neuromuscular disorder - this will involve seeing a neuromuscular specialist (a type of neurologist). ...Read more
Team effort: This is a complicated issue that grows in complexity over time. In growing children and young adults when the scoliosis begins to compromise pulmonary function, surgery becomes a consideration. Well before then the patient should be evaluated by an experienced scoliosis spine sugeon and experienced n-m pediatric neurologist. Bracing, physical therapy and pulmonary functions need to be followed. ...Read more
My medical chart states I have neuromuscular disease. What is this? I know I'm suspected to have MS.
No diagnosis yet: Neuromuscular disease is a category of disease. Sounds like your doctor's suspect something like MS but have not made the formal diagnosis yet (maybe tests are pending). ...Read more
Various mechanisms: Myotonic dystrophy causes heart block, may lead to sudden death, and may require a pacemaker. All people with muscular dystrophy develop cardiomyopathy and may get congestive heart failure. Multiple sclerosis and amyotrophic lateral scerlosis don't usually cause cardiac complications. ...Read more
Why are long-term trached and vented patients with a neuromuscular disease who are otherwise healthy more prone to acquiring pneumonia? Thank you:)
Several reasons: There are a couple of reasons. First the trach itself is a foreign body and gets colonized with bacteria, (that is bacteria grow on and around it) some of these bacteria can make their way into the lung. People with nmd may have a worse cough and are less mobile than others this makes clearing secretions from the lungs more difficult, as the secretions may contain bacteria, infection results. ...Read more
Which one?: Duchenne muscular dystrophy certainly can be accompanied by brain malformations, seizures, intellectual disability, adhd, learning disabilities (if iq is average or above), behavior problems & more.. Some are & some aren't. Since you didn't specify, here's the mda's list with info about each type: http://mda. Org/publications/teachers-guide/neuromuscular-disease-descriptions. ...Read more
What is "rare atrophic muscle fibers in a bkgrnd with non specific changes"? Is it positive for a neuromuscular disorder? Symp's, all over musle pain.
Atrophic fiber: If it is a specific for diagnosis of NMD, it is reported as diagnostic/suggestive/confirmatory etc. That's probably a nonspecific (not suggestive of NMD) finding. If you have concerns, you may talk to the pathologist who reported it. ...Read more
IVIG treatment: IVIG is helpful for curing a condition called AIDP, or Guillain Barre syndrome, which is a type of neuropathy. It's cousin, CIDP, is treated by IVIG, but it is not cured. Myasthenia gravis is a condition that causes weakness. It is also treated with IVIG, but it is not cured. Few illnesses can be cured in neurology, but many can be treated. ...Read more
Rt side of body face to foot is skinnier than left but all results are coming out normal terrified of neuromuscular disorder but neuro says emg clean?
Congenital?: There's several possibilities you may have been born this way are just now noticing a difference in size or this may be a matter of how you perceive left and right on your body. If you do not get this sorted out you might want to get a second opinion from another specialist. ...Read more
Pulmonary function test was really good but mip and mep were a little low. Terrified of neuromuscular disease now. Can this be normal?
Insufficient data: Please repeat your post but this time include your doctor's answer to your question; or, if you haven't asked your doctor this question, please let us know why not. Thanks. ...Read more
How to understand nonspecific neuromuscular disorder causing esophageal motility disorder (inadequate peristalsis) if no diagnosis known & normal bloodtests?
Muscle coordination: The esophagus is just a long muscle. There has to be coordination to push food from your mouth to your stomach and sometimes the coordination of this muscle does not work effectively leading to a motility disorder. Just like your skeletal muscles sometimes cramp and get tired and don't work well this same process can happen to the esophagus muscle. ...Read more
Is it possible that succinylcholine drugs (nicotinic depolarizing neuromuscular blocker) decrease intraocular pressure?
No: Succinylcholine is known to increase intraocular minimally when given to secure the airway. The increase is small and passing, therefore it has been used in patients with increased intraocular pressure. ...Read more
Can succinylcholine drugs (nicotinic depolarizing neuromuscular blocker) decrease intraocular pressure? Any answers appreciated!
Succinylcholine actually causes an increase in intraocular pressure for about 10 minutes after administration.
Classic teaching was not to use succ in people with open globe injuries. There are situations, though, where using succ with other agents that lower IOP is preferred because it makes intubation more smooth, avoiding hypertension and airway reactivity that is worse for the situation anyway ...Read more
Is there any permanent cure for neuromuscular pain and muscle spasm in chest and back? Which is better - drugs or physiotherapy?
Do any psychiatric drugs or their withdrawals lead to arrythmias or to the development of sleep apnea or is this neuromuscular or a different issue?
Simplify PLEASE!!: You have crammed several different questions together! Some psychoactive drugs could/can prolong the qt interval & thus might contribute to an arrhythmia. Cocaine use resulting in arrhythmia is a leading cause of sudden cardiac death in young people- even athletes (len bias) some drugs suppress respiratory drive, leading to apnea, such as the dangerous combo of opiate pain drugs with tranquilizers. ...Read more
Will blepharoplasty help droopy eyelids caused by myasthenia gravis? I have the neuromuscular disorder known as myasthenia gravis which has caused my lower eyelids to be droopy. This is becoming an increasing problem since it is effecting both my vision a
Ptosis surgery: Myasthenia affects the levator muscle of the eyelid creating a droop in the eyelid. Usually medical treatment can alleviate most symptoms but also a tightening or shortening of this muscle helps to raise the eyelid. Removing the excess skin also can help in people with lots of heavy excessive skin. Try to visit an oculoplastic surgeon for this issue. ...Read more
Are there any other neurological or neuromuscular disorders besides myasthenia gravis whose symptoms can be/are worsened by taking doxycycline?
Thenar on dom hand is smaller, 2 clean emgs, but weaker when putting resistance against thumb, scared about ALS or neuromuscular disorder but dr isnt.
Hand weakness: Als or a neuromuscular disorder is unlikely your case. Als or amyotrophic lateral sclerosis occurs most frequently in men 40-50 years of age. The larger muscle groups of the arms or legs are affected first and manifest as difficultly walking or incoordination. Occupational therapy can help to improve hand strength. ...Read more
Is there a neuromuscular disease or anything than can cause right sided atrophy or weakness all at once half of face and throat decrease sensation to?
Need MRI: If symptoms started suddenly, then not likely neuromuscular disease...You need an MRI to look at the brainstem and cervical spine (neck). There are many things that could cause these symptoms. Neuromuscular disease is more likely to cause gradual onset and bilateral weakness or atrophy. ...Read more
Hi I am a pharmacist I want to know if nicotine can bind to nicotinic receptor on neuromuscular junction or only on ganglionic receptors?
Why do we shivering in case of (very cold weather & fear)? Is the neurotransmitters or neuromuscular junction play a role in these conditions? How!
When cold, it's your body generating heat
when your scared, its the release of adrenalin, the fight or flight reflex. ...Read more
No: Neuromuscular blocking agents (nmbs) are one of the components of general anesthesia, but you require many more medications to complete the job. Nmbs facilitate the placement of an endotracheal tube, and improves operating conditions for the surgeon. They do not put or keep you asleep. ...Read more
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