Doctor insights on:
Medicine For Mylocel Allergy
Mylocel allergy: Mylocel (Hydroxyurea) is a chemotherapy medication. An allergy occurs when your body’s immune system creates antibodies to a foreign substance causing a reaction that can be mild to severe. For potential adverse effects see: http://www.webmd.com/drugs/2/drug-20583/mylocel-oral/details ...Read more
Allergies occur when your immune system is triggered by envirionmental factors it should ignore--for example, pollen in the air, or dander on a cat or dog--and creates cells to fight against them. An allergic reaction typically causes itching, congestion, or drainage, and ...Read more
If a PLT is normal but starts to fall (even getting down to 8) & this is suspected to be a drug effect (Hydroxyurea) & the drug is ceased & the low PLT resolves itself within 7 days then would an undetected infection stop the PLT from normalising?
May i assume that: you're referring to your platelets and that they got down to 80,000? If not, you can ignore this response! Hydroxyuria can interfere with the production of platelets and discontinuing it may allow the platelet count to return to normal. An "undetected infection" shouldn't, by itself, prevent the platelets from normalizing, especially if they've already done so. Dr. Anne ...Read moreSee 1 more doctor answer
Antimetabolite: Mylocel, or hydroxyurea, is a form of chemotherapy that works to lower blood counts particularly in patients with leukemia such as chronic myelogenous leukemia and myeloproliferative disorders including polycythemia rubra vera and essential thrombocytosis. Short term side effects may include nausea, hair loss, diarrhea, poor appetite, and nail thickening. Long term effects may include infertility. ...Read more
1 month old : Homozygous hemoglobin E disease (genetic; inherited from both parents) gives mild beta thalassemia & anemia & mildly enlarged spleen; probably doesn't need treatment. Hgb E beta thalassemia disease (E from 1 parent, beta thal from the other): severe incurable disease. Hydroxyurea safe in infants. My guess: start early as possible after 1 mo old. Do discuss this with your pediatric hematologist. ...Read more
"Hydroxyurea may affect fertility (ability to have children), whether a man or a woman."Please advice..
Chemotherapy: it is a chemotherapy drug (a mild one, that doesn't have severe side effects, once it has been checked, worries about it lowering blood counts too much are not much). It does lower sperm quality and that effect can last after it is stopped. http://www.ncbi.nlm.nih.gov/pubmed/17316339 ...Read more
Depends on situation: What is the reason Hydroxyurea is being given? One use of Hydroxyurea is to treat resistant chronic myelocytic leukemia (cml, a cancer of white blood cells). Cancers increase risk of blood clots (dvt), which can be treated w enoxaparin (clexane) in such a case, both would be given. If in hospital, meds like enoxaparin can be used to prevent dvt.Other scenarios exist in which both could be used. ...Read more
ET: When deciding whether to recommend hydrea, (hydroxyurea) the md takes into account patient's age, underlying cardiovascular risk factors, ; prior history of blood clots. The number of platelets is irrelevant if a patient is otherwise healthy. I have plenty of patients with platelet counts around 1 million. Look for an article from blood journal called "how i treat essential thrombocythemia" for a good summary. ...Read more
Is there any chances of getting cancer if the normal person takes hydroxyurea or anagrelide more than a month?
I say no: The talk of an increased leukemia risk has been with us since the 1970s without anybody being able to measure it. If it's real, it's tiny. Anagrelide isn't under suspicion. If some overzealous practitioner went after a high platelet count without good reason, I'm sorry but you'll be fine. Why do you ask? ...Read more