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Doctor insights on: Medicine For Methotrexate Allergy

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What is the definition or description of: Methotrexate allergy?

What is the definition or description of: Methotrexate allergy?

Methotrexate allergy: Methotrexate is an anti-inflammatory drug routinely used to treat skin and joint diseases. In rare cases patients may develop a true allergic reaction. These include a rash, sores in the nose or mouth, enlargement of the lymph nodes, or rarely, lung disease. This is the most common drug prescribed by a rheumatologist. I am happy to do a consult if needed. ...Read more

Methotrexate Allergy (Definition)

Methotrexate is an anti-inflammatory drug routinely used to treat skin and joint diseases. In rare cases patients may develop a true allergic reaction. These include a rash, sores in the nose or mouth, enlargement of the lymph nodes, or rarely, lung disease. This is the most common drug prescribed by a rheumatologist. I am happy to do ...Read more


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41 year-old woman having lupus-like symptoms, angioedema and low complement levels.....?

41 year-old woman having lupus-like symptoms, angioedema and low complement levels.....?

Lupus: This sounds like a diagnosis of lupus. Finish and additional work up and be seen by a rheumatologist and. Other needed sub specialist. All the best. ...Read more

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Need to know about a drug called methotrexate?

Need to know about a drug called methotrexate?

Folic acid inhibitor: It inhibits Folic Acid and can help treat inflammatory disorders like rheumatoid arthritis, psoriasis, tumors, etc, it can help vasculitis also whether it is due to an inflammatory or infectious etiology. It needs to be carefully monitored, can cause liver disease so we recommend no alcohol, can cause low blood counts and mouth ulcers and hair loss so we supplement therapy with folic acid. ...Read more

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Can methocarbamol have a drug interaction with methotrexate?

Can methocarbamol have a drug interaction with methotrexate?

Here's a link...: Consider checking this: http://www. Drugs. Com/drug_interactions. Php ...Read more

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Taking methotrexate and it says u can die if u take it everyday and it's a cancer chemo drug is this true?

Taking methotrexate and it says u can die if u take it everyday and it's a cancer chemo drug is this true?

Methotrexate: It is used for cancer and also in inflammatory joint disease such as rheumatoid arthritis. In rheumatologiic disorders it is used in smaller doses once a week. Like all drugs it has side effects and needs to be monitored carefully by a rheumatologist or oncologist based on who is prescribing for what reason. ...Read more

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Methotrexate injections and pills didn't work for scleritis and was wondering if remicade (infliximab) is good medicine for the scletitis?

Methotrexate injections and pills didn't work for scleritis and was wondering if remicade (infliximab) is good medicine for the scletitis?

Resistant scleritis: Initial therapy always requires systemic nsaids, glucocorticoids, or other immunosuppressives (rituximab & cyclophosphamide). Cyclosporine & mycophenolate may also work. Azathioprine or mtx may be most beneficial for maintenance. Tnf Alpha inhibitors (eg infliximab) may be effective in resistant disease. Scleritis should ideally be managed by ophthalmologist+rheumatologist experts. ...Read more

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Can I take other medicines if I take methotrexate?

Can I take other medicines if I take methotrexate?

Yes: We use it with a lot of different medications. Whenever you take Methotrexate you need to be monitored. We advise no alcohol because alcohol plus Methotrexate increases the risk of liver disease. ...Read more

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What is a alternative medicine to methotrexate for jia?

What is a alternative medicine to methotrexate for jia?

Biologics: Injected weekly low dose Methotrexate is clearly a good drug for juvenile arthritis but doesn't come close to an ideal combination of weekly Methotrexate (12.5-20mg) and a biologic (Enbrel, Remicade, (infliximab) Humira, Orencia).If a patient cannot take Methotrexate due to liver disease or extreme sensitivity to it, then a sufficient dose of a biologic med alone will often work to put disease into remission. ...Read more

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I'm on drug trial for toccilizumab with methotrexate, what to do about liver problems?

I'm on drug trial for toccilizumab with methotrexate, what to do about liver problems?

You will be monitore: Your will be monitored in the trial for liver problems. Each of these drugs methotrexate and tocilizumab can possibly cause liver problems. The trial protocol will decide about medication dose adjustment. You may have no liver problems with either of these. ...Read more

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Can you tell me about a drug trial for toccilizumab with methotrexate had liver problems?

See details: What disease are you treating with it? I will assume it is ra. In my practice, I have found this to be a very effective therapy with reasonably low risk. Routine labs need to be checked including lipids. ...Read more

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How long does methotrexate stay in your system after you stop taking drug. I am having a allergic reaction to the medicine.

How long does methotrexate stay in your system after you stop taking drug. I am having a allergic reaction to the medicine.

Rapidly leaves: 1/2 life depends on dose 3-10 hours with low dose and 8-15 hours with high dose

We usually say it is out after 5 1/2 lives bt there are tissue effects too - maybe 3 weeks ...Read more

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I keep forgetting to take my methotrexate, im starting to get charlie horses. Can this be a result from not taking medicine?

I keep forgetting to take my methotrexate, im starting to get charlie horses. Can this be a result from not taking medicine?

Hard to say: As it's not clear why you take methotrexate. Remember, as it's very much possible that it is unrelated too. Best to try to make sure you are more consistent about your methotrexate use and if the charlie horses persist or a very debilitating, schedule an appointment with your doctor. ...Read more

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Are the drugs Methotrexate and Misoprostol used together for anything else other than abortions?

Maybe: Methotrexate is used in (many cancers) chemotherapy, rheumatoid arthritis, ectopic pregnancies, and molar pregnancies. Misoprostol is used in stomach ulcers (its FDA approved use), bleeding after a delivery of a baby, and bleeding after a miscarriage. We also sometimes use it in place of D&C to prevent an incomplete miscarriage or in term pregnancies to expel a retained placenta. ...Read more

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Since methotrexate and imuran (azathioprine) are not working on scleritis I have what is the next step in terms of medicine.

See below: It depends if you have coexisting autoimmune disease present such as rheumatoid as it may which medication can be used. Cellcept, (mycophenolate mofetil) biologics, prednisone, and others could be used. ...Read more

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I started imuron for scleritis at 50 mg in am and 50 mg in pm and is this good drug for scleritis. No luck w/steroids and methotrexate.

I started imuron for scleritis at 50 mg in am and 50 mg in pm and is this good drug for scleritis. No luck w/steroids and methotrexate.

Cautiously yes: Scleritis is painful, and can have severe complications if not treated. Treatment often involves strong immune suppressant medications like Imuran (azathioprine). These drugs can also have serious side effects. You must be monitored closely by an ophthalmologist and a rheumatologist during treatment and afterwards. Auto-immune diseases such as lupus may cause scleritis. ...Read more

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Is 20mg of methotrexate orally a good medicine for scleritis and how long does it take to work?

Is 20mg of methotrexate orally a good medicine for scleritis and how long does it take to work?

Depends: Scleritis can be caused by different problems since slceritis just means that your sclera are inflamed. If it's been determined to be an autoimmune condition, then Methotrexate may be helpful. However, low dose weekly Methotrexate injected under the skin is a much more effective way to take it (more medicine is absorbed and fewer side effects).Methotrexate usually takes 2-3 months to start working. ...Read more

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What is the average to maximum dosage foe methotrexate for scleritis and since it is not working what are other medicines that can be prescribed.

See below: Usually 25 mg if all labs are normal. You did not mention whether you have a coexisting autoimmune disease such as ra. Having an coexisting autoimmune diseases often dictates what therapy would best work. Biologics, high dose prednisone, and azathioprine are used in general. ...Read more

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Have been on 20mg methotrexate since 8.1.11. Immediately felt almost zero symptoms. Labs are good. How long should I continue on the medicine? Thanks

As long as directed: If your doctor started you on Methotrexate for a given condition. I'm assuming rheumatoid arthritis or lupus perhaps. Then you should continue to take the medicine as directed by your doctor. Provided of course your body is tolerating the Methotrexate and your follow up tests are good -including liver function. ...Read more

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Metoprolol side effects, is this medicine or methotrexate increased LDL cholesterol?

Metoprolol side effects, is this medicine or methotrexate increased LDL cholesterol?

Wouldn't blame meds: I would think more likely it would be dietary or genetic factors affecting an LDL cholesterol. True, the metoprolol could adversely affect the lipid profile but I think it's relatively unlikely. I would recc talking to your doctor about it more. There are other options for blood pressure management out there.
Take care. ...Read more

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Any recommendations for my condition psoriatic arthritis not to eat or drink and what can I do when I start the medicine methotrexate

Psoriasis and gut: Psoriasis is an autoimmune state. Autoimmune means your body is fighting itself. Why? Usually it is triggered by stress of some kind. Address this with managing stress cleaning the gut (probiotics and clean eating). Methotrexate is harsh on the liver so eat liver friendly diet like greens, cruciferous and lemon. Do breathing exercises when stressed. Address sleep issues. ...Read more

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What is the blood work protocol while taking hydroxychloroquine and methotrexate? I've had bloodwrk once in the year I've been taking these 2 drugs.

What is the blood work protocol while taking hydroxychloroquine and methotrexate? I've had bloodwrk once in the year I've been taking these 2 drugs.

Tests: Blood tests for monitoring of methtrexate consist of CBC and platelet count as well as liver function tests to keep track of potential liver and bone marrow damage. The tests can be done every 3 to 6 months or as needed as determined by any symptoms. Plaquenil (hydroxychloroquine) rarely causes blood problems but an annual eye exam is important. ...Read more

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How long does the drug methotrexate take to give a reduction in pain levels.?

Weeks to months: Methotrexate works by reducing the function of the cells that are causing inflammation in the joint tissues.
People with swollen and painful joints whose rheumatoid arthritis has not improved with initial, non-drug therapies will most likely be prescribed methotrexate for RA management. But it may take weeks to several months until the full benefits of methotrexate are noticeable ...Read more

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Are there any effective anti-tnf drugs for RA without methotrexate?

Yes: If a person can not or will not take Methotrexate with a tnfi, one may be able to substitute the Methotrexate for another NSAID such as lefluemide, sulfasalazine, Hydroxychloroquine or in some settings use the tnfi alone. ...Read more

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Has anyone tried anti-tnf drugs for RA without using methotrexate at the same time?

Yes: Though the drug studies were set up to have these tnf agents used in combination with Methotrexate (mtx), many patients do take tnf agents without mtx. Certain tnf agents work better than others if mtx is not being taken. Speak to your rheumatologist if you are considering going off mtx. ...Read more

Methotrexate (Definition)

Methotrexate was originally used in the early 1950's as a treatment for cancer but was also found to be effective in many other diseases including rheumatoid arthritis and psoriasis. It has anti inflammatory and immunosuppressive properties which make it an excellent first line therapy for RA ...Read more


Dr. John Chiu
2,638 Doctors shared insights

Allergies (Definition)

Allergies occur when your immune system is triggered by envirionmental factors it should ignore--for example, pollen in the air, or dander on a cat or dog--and creates cells to fight against them. An allergic reaction typically causes itching, congestion, or drainage, and ...Read more