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Doctor insights on: Medicine For Isosorbide Dinitrate Allergy

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How does isosorbide dinitrate or mononitrate help prevent angina attacks?

How does isosorbide dinitrate or mononitrate help prevent angina attacks?

Supply and demand: Angina is caused by heart muscle not getting enough blood to meet its needs, think supply vs demand. By relaxing smooth muscle in the walls of coronary arteries, nitrates increase blood flow. They also dilate the body's veins, so less blood returns to the heart, and the heart walls are less stretched outwards. This reduces tension on the heart wall muscle, and hence demand for oxygen/blood. ...Read more

Dr. John Chiu
2,638 Doctors shared insights

Allergies (Definition)

Allergies occur when your immune system is triggered by envirionmental factors it should ignore--for example, pollen in the air, or dander on a cat or dog--and creates cells to fight against them. An allergic reaction typically causes itching, congestion, or drainage, and ...Read more


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Should I take isosorbide dinitrate or isosorbide mononitrate?

Should I take isosorbide dinitrate or isosorbide mononitrate?

You should take: Whichever your health care provider has recommended. Mononitrate has a longer half life and less likely to develop tolerance. Used more commonly in stable angina patients. Ask your health care provider this questions as s/he has your medical history available. ...Read more

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Who should not use isosorbide dinitrate?

Who should not use isosorbide dinitrate?

Isosorbide dinitrate: "Allergic reactions to organic nitrates are extremely rare, but they do occur. The isosorbide dinitrate tablet is contraindicated in patients who are allergic to ISDN or any of its other ingredients." See: http://dailymed. Nlm. Nih. Gov/dailymed/drugInfo. Cfm? Setid=8bb91825-b63e-44aa-8edd-4326823f3009 ...Read more

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Could you explain what is isosorbide dinitrate (isoket spray)?

RU in the UK?: Isoket spray is not available in the usa. It's a form of Nitroglycerin and it's used under the tongue for rapid relief of angina spells. In the usa, we use Nitroglycerin as a tablet or a spray and we use Isosorbide Dinitrate tablets for longer lasting relief/prophylaxis of angina. ...Read more

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In a patient with migraines, will their frequency increase if the patient takes isordil (isosorbide dinitrate)?

In a patient with migraines, will their frequency increase if the patient takes isordil (isosorbide dinitrate)?

Isordil (isosorbide dinitrate) & Headaches: Isordil is nitroglycerine, a vasodilator for the heart (seldom other) which can cause headaches. It is dose dependent, the higher the most likely headache. You may take tylenol (acetaminophen) for it. If your migraines get worst talk to the cardiologist about it. ...Read more

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What are some of the disadvantages by using isosorbide dinitrate?

Minor: Some people have issues with headaches or low blood pressure. Both of these resolve if the medication is stopped. ...Read more

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What's the difference between isosorbide mononitrate vs isosorbide dinitrate?

How long they last: The main difference is how long they last. Most dinitrate products are designed to be taken at least 2 x a day where as most of the mononitrate products once a day. They both are quite effective at controlling angina when appropriately prescribed. Some side effects thought a bit less with mono v. Di, but that varies a lot from person to person. ...Read more

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What is isosorbide dinitrate?

Isosorbide dinitrate: Iosorbide dinitrate is a medication used to treat/ prevent angina. ...Read more

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How does isosorbide dinitrate and hydralazine work in treating congestive heart failure?

How does isosorbide dinitrate and hydralazine work in treating congestive heart failure?

A-HEFT Trial: A large trial looked at the combination of hydralazien and Isordil (isosorbide dinitrate) with african american patients and showed a benefit of improving heart failure status, on top of standard medical therapy. It is thought to be believed due to lack of Nitric Oxide delivery to endothelium in african americans, that is improved by this therapy. Blood pressure tends to be higher in the first place, which improves. ...Read more

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Is isordil (isosorbide dinitrate) for chest pressure contraindicated in patients with constrictive pericarditis?

Is isordil (isosorbide dinitrate) for chest pressure contraindicated in patients with constrictive pericarditis?

Generally no: It is not considered to be contraindicated, neither is it considered a treatment. Why is it being considered? ...Read more

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To control CHF is it normal to prescribe hydralazine alone or with isosorbide dinitrate? She has no hypertension, but AF. Headache+AF worsens wt these

To control CHF is it normal to prescribe hydralazine alone or with isosorbide dinitrate? She has no hypertension, but AF. Headache+AF worsens wt these

Yes: The combination of hydralazine and isosorbide reduce filling pressures in the heart, reduce the amt of work the heart must do, & reduce the changes in structure to the heart that heart failure brings. This is for heart failure where the ejection fraction is less than 40%. ...Read more

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How effective is isosorbide dinitrate for treating coronary artery disease (CAD)?

Isosorbide dinitrate: Iosorbide dinitrate is beneficial in the treatment & prevention of angina. ...Read more

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If you are feeling these side affect numbness tingling of hands legs and feet from taken carvedilol isosorbide dinitrate and hydralazine?

If you are feeling these side affect numbness tingling of hands legs and feet from taken carvedilol isosorbide dinitrate and hydralazine?

Antihypertensives: The medications above are used to treat high blood pressure. They are usually tolerated well but uncommonly do have side effects. New onset numbness and tingling has many causes and isn't necessarily related to your medications. ...Read more

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Can pregnant women take isosorbide dinitrate?

Isosorbide dinitrate: Isosorbide dinitrate is FDA Pregnancy Category C (Risk cannot be ruled out.) ...Read more

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Could the drugs toprol, (metoprolol) isosorbide, and lotensin create dehydration in the human body?

Could the drugs toprol, (metoprolol) isosorbide, and lotensin create dehydration in the human body?

See below: Not likely by themselves, look if there are diuretics such as Furosemide included in your other medications, or combined hydrochlorothiazide combined with your medications. ...Read more

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Can using 0.3ml lidocaine with 1:100, 000 epinephrine during dental work interacts with bystolic, (nebivolol) benicar/hct or isosorbide mononitrate medicine.?

Can using 0.3ml lidocaine with 1:100, 000 epinephrine during dental work interacts with bystolic, (nebivolol) benicar/hct or isosorbide mononitrate medicine.?

Probably not: Although Lidocaine is a vasodilator, there is no clinical evidence of any drug interactions or special precautions needed. However, if during the injection, some of the anesthetic were to be introduced directly into a blood vessel, the Epinephrine could cause a minor and short acting increase in heart rate. ...Read more

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Is isosorbide mononitrate a beta blocker?

Is isosorbide mononitrate a beta blocker?

No: No, Isosorbide Mononitrate (imdur) is a nitrate class drug and used for vasodilation. ...Read more

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Can isosorbide trinitrate (iv) given to pat. With hypertensive crisis and intracerebral hemorrhage?

Can isosorbide trinitrate (iv) given to pat. With hypertensive crisis and intracerebral hemorrhage?

Nitrates, Yes...: I'm not familiar with isosorbide trinitrate, but nitrates, Nitroglycerin and nitroprusside are one of many treatments used for hypertensive crises when control of blood pressure is essential. ...Read more

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Define isosorbide monotrite usage, dosage. Any issue if it is taken for long time. Would it cause heart burn.

Define isosorbide monotrite usage, dosage. Any issue if it is taken for long time. Would it cause heart burn.

Slow titration: I will start 5 mg twice a day. Increased slowly follow by physician up to 40mg. More if approve by physician. It's s vasodilator and in theory could relax the lower esophageal sphincter causing gerd symptoms. ...Read more

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What is the very first signs of congestive heart failure. Should I be taking imetoprolol tartrate, & isosorbide monomitratate? If I have chf?

What is the very first signs of congestive heart failure. Should I be taking imetoprolol tartrate, & isosorbide monomitratate? If I have chf?

CHF: Shortness of breath, leg swelling, fatigue are common. Both meds are good. You may want to talk with your doctor regards to "ace inhibitors and water pills. Depending on how bad your CHF is, these will add bebefit to meds you are already taking. If your ef is less than 35%, you may need a defibrillator. ...Read more

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Diagnosed with circumflex muscle bridge. Chest pain treated with daily isosorbide. Cardioligist also suspects microvasc. Spasms. Need more information?

Diagnosed with circumflex muscle bridge. Chest pain treated with daily isosorbide. Cardioligist also suspects microvasc. Spasms. Need more information?

Uncertain significan: Muscular bridge is when a coronary artery lies beneath the heart muscle. So the artery is squeezed during each cardiac contraction and therefore interrupts blood flow. It may or may not cause chest pain in patients with normal coronaries. Microvascular dysfunction is when the small capillaries in the heart fail to respond or adopt to a vasodilatory stimulus often suspected in women normal arteries ...Read more

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What happens if I took two isosorbide pills in one day?

Isordil (isosorbide dinitrate): If you space the pills about 6 hours apart and they are not long acting isordil, (isosorbide dinitrate) you get the effect of the first pill repeated but not increased ...Read more

Dr. Jerome Zacks
20 Doctors shared insights

Isosorbide Dinitrate (Definition)

Isosorbide dinitrate is a nitrate based agent which is a kind of chest ...Read more


Dr. William Singer
13 Doctors shared insights

Dilatrate Sr (Definition)

Dilatrate SR is a nitrate based agent which is a kind of chest ...Read more