Top
30
Doctor insights on: Medicine For Imatinib Allergy

Share
1

1
What is the definition or description of: Gleevec (imatinib) allergy?

What is the definition or description of: Gleevec (imatinib) allergy?

Gleevec: Gleevec (imatinib) is a Chemotherapy medication. An allergy occurs when your body’s immune system creates antibodies to a foreign substance causing a reaction that can be mild to severe. For potential adverse effects see: https://www.drugs.com/gleevec.html ...Read more

Dr. John Chiu
2,630 doctors shared insights

Allergies (Definition)

Allergies occur when your immune system is triggered by envirionmental factors it should ignore--for example, pollen in the air, or dander on a cat or dog--and creates cells to fight against them. An allergic reaction typically causes itching, congestion, or drainage, and ...Read more


2

2
Is imatinib mesylate 400mg per day the right medicine for cml?

Is imatinib mesylate 400mg per day the right medicine for cml?

Yes: It is the right medicine for cml.
In addition to imatinib mesylate- tasigna (nilotinib) is also available as a first line therapy for cml. ...Read more

Emily Lu Dr. Lu
2 doctors agreed:
3

3
If you don't have the gene to use gleevec, (imatinib) will the drug help at all?

Emily Lu Dr. Lu
2 doctors agreed:
If you don't have the gene to use gleevec, (imatinib) will the drug help at all?

No: Gleevec (imatinib) is a targeted cancer therapy, which means that it is only effective against cancer cells with a particular genetic mutation. It will not be effective against cancer cells without the mutation. ...Read more

4

4
Hi all, could someone tell me if you can heal blood cancer disease with gleevec (imatinib) medicine?

Hi all, could someone tell me if you can heal blood cancer disease with gleevec (imatinib) medicine?

A treatment for CML: Gleevec (imatinib) is one of the treatments for one type of leukemia, chronic myelogenous leukemia. It is not a cure. ...Read more

5

5
I'm wondering can the drug imatinib (gleevec) cause graying or white hair?

I'm wondering can the drug imatinib (gleevec) cause graying or white hair?

Yes. : Yes, some patients on imatinib report graying of the hair due to the drug. The good news is that CML patients taking imatinib have the possibility of living long enough to get gray hair from old age, an option not available before that drug was developed. So keep the side effect in perspective. It is safe to use hair dye while on imatinib. ...Read more

6

6
I am a cml patient till 10 years. Name of the medicine is gleevec (imatinib) imtanib. Is there any problem in pregnancy?

I am a cml patient till 10 years. Name of the medicine is gleevec (imatinib) imtanib. Is there any problem in pregnancy?

Yes: You can not take Gleevec (imatinib) during pregnancy as Gleevec (imatinib) is considered to be as category d meaning there is evidence of human fetal risk. If you are pregnant, interferon is something you can be on. Interferon is in category c. Please discuss in detail with you oncologist/hematologist. ...Read more

8

8
I am a cml patient and I am getting imatinib mesylate 400mg daily now I am having joint pains and I am getting very weak... Prescribe some medicine.

I am a cml patient and I am getting imatinib mesylate 400mg daily now I am having joint pains and I am getting very weak... Prescribe some medicine.

You really need to: Coordinate this with your oncology team. They have a better grasp of your relatively complicated medical history, your other meds, what is safe to prescribe, and the dosing. We would really be overstepping boundaries if we were to start pain management exclusively via telemedecine. They know how your liver and kidneys are doing, and how all the drugs need to be juggled. Hang in there — stay strong ...Read more

9

9
Can you tell me how imatinib inhibit kit?

Can you tell me how imatinib inhibit kit?

Imatinib: "Imatinib mesylate is a protein-tyrosine kinase inhibitor that inhibits the BCR-ABL tyrosine kinase, the constitutive abnormal tyrosine kinase created by the Philadelphia chromosome abnormality in CML." See: http://www.rxlist.com/gleevec-drug/clinical-pharmacology.htm ...Read more

10

10
What are the side effects of imatinib in leukemia?

What are the side effects of imatinib in leukemia?

No serious side effe: There are but few mild side effects from taking imatinib. Most people find it well tolerated. There may be some non-specific symptoms like muscle aches, mild indigestion or impaired appetite or nausea. ...Read more

11

11
What's imatinib mesylate?

What's imatinib mesylate?

Enzyme inhibitor: This drug, gleevec, (imatinib) is used to treat chronic myeloid leukemia and gastro-intestinal stromal tumors. It acts by inhibiting and enzyme produced by tumor cells. ...Read more

13

13
Can anyone tell me side effects of taking gleevec (imatinib)?

Imatinib/gleevec: Please read here for detail answer:

http://www.Nlm. Nih. Gov/medlineplus/druginfo/meds/a606018. Html. ...Read more

14

14
What is the definition or description of: side effects of gleevec (imatinib)?

What is the definition or description of: side effects of gleevec (imatinib)?

Chemotherapy related: Pretty typical. Nausea, vomiting low blood counts, infection risk. ...Read more

15

15
What should I do if I have to take gleevec (imatinib) for leukemia and it's hard to work because it makes me so sick?

Call Oncologist: There are a large amounts of information on different approaches to manage toxicity based upon the response of the cml. It is expected that people will live for decades with CML on treatment. There are dose changes and other agents to be considered.
Don't stop the drug. Have a discussion with your oncologist about the options for you to be functional. ...Read more

16

16
How does imatinib work?

How does imatinib work?

Imatinib: "Imatinib mesylate is a protein-tyrosine kinase inhibitor that inhibits the BCR-ABL tyrosine kinase." See: http://www.rxlist.com/gleevec-drug/clinical-pharmacology.htm ...Read more

17

17
Is there a generic form of imatinib?

Is there a generic form of imatinib?

Not in the USA: Generic Gleevec (imatinib) is not fda approved and will not be until the patent on Gleevec (imatinib) expires in 2015.
Natco an indian drug company also makes a generic version of Gleevec (imatinib) called veenat. ...Read more

18

18
Anyone know of effects with gleevec (imatinib)?

Gleevec (imatinib) info: Open this link:

http://www.Nlm. Nih. Gov/medlineplus/druginfo/meds/a606018. Html.

Get a more detailed answer ›
19

19
What testing do I need to have in order to get gleevec (imatinib)?

C-kit analysis: Whether patients with gist are candidates for Gleevec (imatinib) depends on the status of a particular gene called c-kit, or cd117. This is a test that must be run on the tumor biopsy tissue and is generally coordinated with the help of the pathology laboratory. In select cases, some patients are candidates for Gleevec (imatinib) regardless of their c-kit results, but this is highly individualized. ...Read more

20

20
Can gleevec (imatinib) cure retinoblastoma?

Can gleevec (imatinib) cure retinoblastoma?

No data yet...: Gleevec (imatinib) inhibits a number of tyrosine kinases in cells (c-kit, pdgfralpha, c-abl). There is very recent data that Gleevec (imatinib) may have activity in retinoblastoma, but these experiments where done on isolated retinoblastoma cells grown in culture. There are no clinical trials showing that Gleevec (imatinib) can treat retinoblastoma. Future clinical trials may be planned to address this question. ...Read more

21

21
I m suffering with cml. And taking imatinib mesylate. Fx?

Clarify question?: What is your question? Imatinib mesylate of Gleevec is one of the first line treatment and has been the standard of care for CML for the last 10 years or so. It is an oral tyrosine kinase inhibitor that inhibits the bcr-abl. In cml, Gleevec has demonstrated a very high response rate, complete hematological/molecular response rate. Newer medication like tasigna, (nilotinib) sprycel now are also available. ...Read more

23

23
Help plz! Can retinoblastoma be treated with gleevec (imatinib)?

Help plz! Can retinoblastoma be treated with gleevec (imatinib)?

Gleevac: Gleevac is not usually the first drug for the treatment of retinoblastoma. There are other drugs that are usually used ...Read more

24

24
What should I do if imatinib mesylate does not dissolve in water?

What should I do if imatinib mesylate does not dissolve in water?

Suspension OK: If you are unable to swallow tablets they can be dispersed in water or other beverage and stirred with a spoon. It should completely disintegrate but not necessarily completely dissolve. It's OK to drink a suspension. If you left some behind in the glass rinse it down with a little more water and drink that too. ...Read more

25

25
What to do if I have a healthy gleevec (imatinib) pregnancy?

What to do if I have a healthy gleevec (imatinib) pregnancy?

Keep it: If you are past 3 months, then it is best to continue to taking Gleevec (imatinib). Stopping it for a few months is another option. The drug is generally safe although there is not a great deal of experience using it in pregnant women, but there have been close to 100 normal pregnancies in my limited experience. ...Read more

26

26
For a synovial sarcoma are imatinib or everolimusm effective?

For a synovial sarcoma are imatinib or everolimusm effective?

These have no: Established role in front line therapy. Are they being offered on a clinical trial? Both are costly, and possibly of theoretic use. Ask for the strength of the data (it will be called a phase ii trial),. ...Read more

27

27
How does imatinib stop the signaling pathway of mutated kit in patients with gist?

How does imatinib stop the signaling pathway of mutated kit in patients with gist?

Inhibits enzyme: The drug fits precisely into a "pocket" in the enzyme encoded by the mutant gene, blocking the enzyme's function. ...Read more

Dr. Liawaty Ho Dr. Ho
2 doctors agreed:
28

28
Is treatment necessary for systemic mastocytosis? I am taking gleevec (imatinib). What would happen if I stopped taking it?

Dr. Liawaty Ho Dr. Ho
2 doctors agreed:
Is treatment necessary for systemic mastocytosis? I am taking gleevec (imatinib). What would happen if I stopped taking it?

D/w oncologist: There are indolent systemic masto, and agressive systemic mastocytosis (asm). Many times, with indolent disease- therapy will be aimed only to control the symptoms- itching, diarrhea etc. If you have an asm- then usually treatment is started. Asm can manifest from slowly progressive to rapid fatal disease. Organ involvement, transformation to other blood DX including acute leukemia can happen. ...Read more

29

29
Can gleevec (imatinib) cause a lump in the breast?

Can gleevec (imatinib) cause a lump in the breast?

No: No. I don't think so. If you have a lump in the breast- you need a mammogram and sonogram to be done. If it is confirmed to be a solid mass- a biopsy should be done to figure out what the lump is. Breast lump has nothing to do with the gleevec (imatinib). Go see you md right away so mammo and sonogram of the breast can be done as soon as possible and biopsy should also be done accordingly. ...Read more