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Doctor insights on: Medicine For Hereditary Ovarian Cancer

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What are the tests for hereditary ovarian cancer?

What are the tests for hereditary ovarian cancer?

Ultrasound: Pelvic/transvaginal ultrasound is the best test after a good physical exam for a suspected ovarian cancer of any kind. ...Read more

Dr. Barry Rosen
4,351 doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


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What are the symptoms of hereditary ovarian cancer?

What are the symptoms of hereditary ovarian cancer?

Same as regular: Ovarian cancer. Unfortunately, there are no specific symptoms in early ovarian cancer. Most women have vague abdominal symptoms and at later stages, abdominal swelling, mass, symptoms from mets, weakness etc. ...Read more

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What is the definition or description of: Hereditary ovarian cancer?

What is the definition or description of: Hereditary ovarian cancer?

More than one member: Hereditary Ovarian cancer(often in combination with Breast Cancer) runs in 10 of Ovarian cancers. It should be considered and confirm by genetic testing if there is high suspicion based on 2 or more first degree relatives(parents, sisters or maternal aunts) suffering from Ovarian or Breast Cancer. The diagnosis is confirmed if you are a carrier for BRCA gene mutation (genetic test which can be don ...Read more

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What genes cause hereditary ovarian cancer?

BRCA 1 and 2: The breast-ovarian cancer (brca 1 and 2) genes are the only ones so far proven to cause susceptibility to ovarian cancer (as high as 50% lifetime risk for ovarian, 85% for breast cancer if you have a mutation. Other ovarian cancer susceptibility genes may be identified by ongoing research. ...Read more

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What is the treatment for hereditary ovarian cancer?

What is the treatment for hereditary ovarian cancer?

Prevention.: Most hereditary ovarian cancer is caused by BRCA genes. The key is prevention. US, blood work and a physical exam every six moths. Oral contraceptives can decrease risk of ovarian cancer. If BRCA positive then removal of tubes and ovaries at about 35 or after childbearing. Need to make a cancer prevention plan with doctor. Also need close relatives to be aware of risk. Hope this helps. ...Read more

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I need a straight answer. What is hereditary ovarian cancer?

I need a straight answer. What is hereditary ovarian cancer?

Genetic Syndrome: Basically this is a familial cancer syndrome. This is due to a genetic defect which is passed down from paretn to child. (can actually come from a man). In the case of ovarian cancer it is usually associated with the brca gene when someone speaks of hereditary ovarain cancer. ...Read more

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How treatable is ovarian cancer with today's medicine?

How treatable is ovarian cancer with today's medicine?

Fairly well: We have modestly good treatment for ovarian cancer. If caught early it is curable in half to two thirds of cases. But commonly it presents as stage 3-4 disease where the cure rate drops to 25-30%. Yet the available chemotherapy can buy several years of good life when patient is treated by a specialist(gynecologic oncologist). Good luck. ...Read more

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Do fertility drugs increase your risk of developing ovarian cancer?

Do fertility drugs increase your risk of developing ovarian cancer?

Minimal: If there is a risk, is with Clomid (clomiphene) after 12 months of use and the risk is minimal. The greatest risk is infertility itself and not the medications. In the grand majority of patients there is no reason to use Clomid (clomiphene) for 12 months. The treatment is usually changed if the patient has not conceived after 4-6 cycles. ...Read more

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Are there new drugs which could improve management of ovarian cancer patients?

Are there new drugs which could improve management of ovarian cancer patients?

Much too broad a ??: Cancer is very complicated and it is evaluated for each patient differently. Speak with an oncologist. ...Read more

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My grandmother may have very advanced ovarian cancer, tests are coming back today. Is ovarian cancer hereditary?

My grandmother may have very advanced ovarian cancer, tests are coming back today. Is ovarian cancer hereditary?

There incresed risk: There is genetic predisposition but most ovarian cancers are not heriditary.If she has brac1;brac2also hnpcc gene.There is increased risk of ovarian cancer if you a menber of your immediate family has ovarian cancer. ...Read more

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Have been diagnosed with ovarian cancer, what are the chances that this was hereditary?

Have been diagnosed with ovarian cancer, what are the chances that this was hereditary?

About 8.5%: Less then 10% of ovarian cancers are currently known to arise from inherited mutations. ...Read more

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Is ovarian cancer more or less likely to be "genetic/hereditary"?

Is ovarian cancer more or less likely to be "genetic/hereditary"?

Often it is not gene: Only 10-20% cases are genetic or hereditary in origin, rest are sporadic or not related to previous family history...Just come out of the blue in more than 80% of cases. ...Read more

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Heard again that fertility drugs are linked to ovarian cancer. Thought that was not true. Now not sure what to believe. Do I need ultrasounds yearly?

Heard again that fertility drugs are linked to ovarian cancer. Thought that was not true. Now not sure what to believe. Do I need ultrasounds yearly?

Infertility Yes Rx N: Infertility and having no children are independent risk factors for ovarian cancer. Some injectable super-ovulation drugs had some initial concern for increasing cancer risk but most believe that any increase in risk is minimal. No specific screening is recommended for ovarian cancer. Ca-125 testing and ultrasound have not been effective at determining who will develop ovarian cancer. ...Read more

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Heard again that fertility drugs are linked to ovarian cancer. Thought that was not true. Now not sure what to believe. Do I need ultrasounds yearly?

No ultrasounds: Anything that stimulates the ovaries can theoretically increase risk for ovarian cancer, whether fertility drugs or the constant stimulation of uninterrupted monthly cycles in women who never get pregnant. However, the risk is low. There is no good screening test for ovarian cancer, so just pay attention to your body and let your doctor know of any abdominal discomfort. And try not to worry! ...Read more

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Can ovarian cancer and breast cancer be hereditary?

Can ovarian cancer and breast cancer be hereditary?

Yes, of course: This is one of the classic hereditary cancer syndromes.

Sorry, i don't have enough characters to be allowed to give you a full asnwer here, but
quoting wikipedia:

http://en.Wikipedia.Org/wiki/hereditary_breast%e2%80%93ovarian_cancer_syndrome. ...Read more

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Can there be any alternative medicine for ovarian cancer rather than chemotherapy?

Can there be any alternative medicine for ovarian cancer rather than chemotherapy?

No, not really: Alternative medicines, if suggested by someone are not likely to be useful. Chemotherapy is the only choice for controlling advanced ovarian cancer. If there are concerns about side effects, they can be controlled and managed by your oncologist. So do not hesitate taking chemotherapy. It would do some and often much good for the patient. ...Read more

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I had testicular cancer and his sister died of ovarian cancer. Is this just a terrible coincidence or could it be hereditary?

I had testicular cancer and his sister died of ovarian cancer. Is this just a terrible coincidence or could it be hereditary?

While these are both: Can be germ cell tumors, there is neither familial or molecular links to cancers of either kid, or the oddity of siblings of opposite sex acquiring them. Most ovarian tumors are not germ cell, but epithelial, the opposite is true of testicular cancer. ...Read more

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Do injectables medicines (e.G. Gonal) that are used along with IUI cause ovarian cancer in women?

Do injectables medicines (e.G. Gonal) that are used along with IUI cause ovarian cancer in women?

Gonadotropins: There is no simple answer, but the answer beat supported by the literature is that women with infertility are at increased risk for ovarian cancer. Menopausal gonadotropins used for fertility treaents do not at this time to be causal of epithelial ovarian cancer. ...Read more

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Curious as to why anti-egfr drugs have been largely unsuccessful for ovarian cancer treatment?

Clever cancer: Cancers are composed of populations of cells which divide and multiply rapidly and which have various abnormal metabolic pathways. Anti-egfr drugs are designed to block one important pathway whereby cancer cells promote blood vessel growth to feed them, but they can activate other pathways to do this when the drug is used, or they can mutate so that the receptor isn't blocked by the drug. ...Read more

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My aunt (dad's sis) and grt-grandma (pat grandma's mom) both died of ovarian cancer. How likely is it hereditary? Would genetic testing be good idea?

Possibly: Two family members with ovarian cancer is not that common. There are a few inherited conditions that increase ovarian cancer risk. I would suggest that you gather all family info you can get hold of (all family with or without cancer) and visit with your gyn or family doc. They will decide of you need to be seen by a specialist in hereditary cancer. ...Read more

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There is a gene you can have that makes you more likely to get breast and ovarian cancer that is hereditary. What gene is that?

There is a gene you can have that makes you more likely to get breast and ovarian cancer that is hereditary. What gene is that?

BRCA mutation: The gene is called brca, and mutations in this gene are associated with an increased risk of breast and ovarian cancer. Check out this link for more info:
www.Cancer.Gov/cancertopics/.../brca. ...Read more

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Stage 3c ovarian cancer in 2011 done several chemo drugs now in liver and have colostomy doc says if no more chemo qual of life 6 mo fair assessment?

Doc may be right: I can not fully answer your question without knowing which chemotherapy drugs have been used(we have 5-6 good drugs for ovarian cancer). But once the cancer becomes resistant to all drugs then life is short...Usually a matter of months than years. But you can get a second opinion from another oncologist if you want to be absolutely certain. ...Read more

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How fast does ovarian cancer grow?

How fast does ovarian cancer grow?

Very fast!: This is a form of cancer that requires quick intervention. ...Read more

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How fast does ovarian cancer spread?

It's variable.: Some ovarian cancers spread very slowly - over years, even. The most common form of ovarian cancer likely spreads more quickly than that (weeks to months), but every patient with ovarian cancer is different. ...Read more

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Where does ovarian cancer spread to?

Where does ovarian cancer spread to?

Pelvis & abomen: Commonly when advaced spreads in the abdomen affecting the peritoneum producing increased intra pelvic and abdominal fluid. As most cancers may spread to liver, lung, brain, bone. Most ovarian cancer produce symptoms only in advanced stages with nonspecific sensations of increased belly or intraabdominally discomfort. Ca 125 is not a screening test because of so many false positives and negatives. ...Read more

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What tests can diagnose ovarian cancer?

CA-125 , ultrasound: Routine screening is not recommended on people with average risk. Family history is a strong risk factor. In these patients ca-125 (it is a tumor marker checked in blood) also transvaginal ultrasound can help early diagnosis. ...Read more

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Can ovarian cancer be felt during exam?

Can ovarian cancer be felt during exam?

In some cases: In some cases of ovarian cancer, a mass (or masses) can be felt in the pelvis with a manual vaginal examination. In advanced cases, a swollen abdomen from ascites can be seen on exam (but this is not specific for ovarian cancer). In most cases of ovarian cancer, the findings on exam are quite nonspecific. ...Read more

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How early can ovarian cancer be detected?

How early can ovarian cancer be detected?

Depends.: It is notoriously hard to detect early. Pelvic ultrasound and family history along with serum ca-125 are some approaches to early detection that have not been particularly effective. Current research is aiming at identifying a serum proteomic signature of early ovarian cancer that can be clinically useful. ...Read more

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What is meant by end stage ovarian cancer?

Not curable: Typically when someone refers to end stage they are describing a case that is not curable. Most of the time these are patients who have developed disease that has spread to parts of the body outside of where the cancer originally developed (i.e. Metastasis). ...Read more

Dr. John Geisler
17 doctors shared insights

Hereditary Ovarian Cancer (Definition)

Hereditary Ovarian cancer(often in combination with Breast Cancer) runs in 10 of Ovarian cancers. It should be considered and confirm by genetic testing if there is high suspicion based on 2 or more first degree relatives(parents, sisters or maternal aunts) suffering from Ovarian or Breast Cancer. The diagnosis is confirmed if you are a carrier for BRCA gene mutation (genetic test ...Read more


Dr. Gurmukh Singh
502 doctors shared insights

Ovarian Cancer (Definition)

A typically silend cancer which ...Read more