Doctor insights on:
Medicine For Hepatocellular Carcinoma
My husband has been diagnosed with hepatocellular carcinoma and he is taking nexavar; I would like to know if you have experience with this drug resu?
Yes: Nexavar, also called sorafenib, is an oral drug that was approved in 2007 for treating hepatocellular carcinoma that cannot be surgically removed. It delays the growth of the tumor, but it does not cure it. Diarrhea, hair loss, and hand/foot syndrome (redness and peeling of hands and feet) are the main side effects. Good luck to you both! ...Read more
Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more
In its early stage, the patient virtually has no symptoms at all. The key to its diagnosis is still professional alertness notably for someone with hepatitis - b, -c, liver cirrhosis, chronic alcohol use, with known abnormal finding in liver function test. These patients are advised to have periodic follow-up with blood tests and liver ultrasound study.
Any doubt, see an expert timely.
Best. ...Read more
Depends on therapy: Its really therapy dependent. Most hcc are related to cirrhosis, usually extensive and multiple and not amenable to therapy. Only early hcc can be amenable to resection and or liver transplant. Transplant is curative, as can be resection in the absence of cirrhosis. ...Read more
Depends on the stage: Liver cancer that is limited to the liver is associated with a number of treatment options and years of life expectancy. Since hcc usually occurs in patients with underlying liver disease, treatment must often be balanced with any potential detriment of treatment to a vulnerable liver substance. Liver transplant remains a viable option for many patients with hcc and liver disease. ...Read more
A Cancer of Liver: Hepatocellular carcinoma (HCC) is a Cancer arising from the Liver. It often occurs in in people who have a chronically damaged liver due to infection with Hepatitis B or hepatitis C Virus or it can be due to use of excessive alcoho, drinking that leads to Cirrhosis which then makes you more prone to develop Liver Cancer (HCC). ...Read more
Liver cancer: Same thing. Hepatoma is older name.Get a more detailed answer ›
The best results are: From surgery, and that depends on the tumors location in relation to the big blood vessel, the portal vein, and the viability of the liver not involved with the tumor itself. If your tumor is not resectable, there are new but expensive medicines that cause response and shrinkage. If the tumor grows or cannot be stopped, the liver will fail. I see some with bony metastasis. Best wishes. ...Read more
Complicated: The answer depends on several factors including the underlying liver disease, the size number and pattern of spread within the liver, and any other medical problems that the patient has that will effect their ability to tolerate therapy. There are several treatments available for hcc. ...Read more
Yes: Many patients demonstrate shrinking of their tumors following chemoembolization. In some cases, tumors can appear entirely inactive after one or several chemoembolization procedures. While some patients unfortunately do not respond as well, chemoembolization is an established treatment for hepatocellular carcinoma that can't be removed surgically. ...Read more
Yes, for Stage 4: Nexavar, or sorafenib, is used to treat advanced, unresectable hepatocellular carcinoma. It is also used to treat patients with advanced kidney cancer. This drug is a multikinase inhibitor and works by decreasing tumor growth and replication, by inhibiting the formation of blood vessels that tumors rely on to get nourishment. This is not a curative treatment, prolonging survival on average 7 mo. ...Read more
Hcc: Liver transplant will take out the tumor and also replace the liver that is at risk for getting new hcc. If the patient is not a candidate for transplant then resection of the tumor would be the best treatment for small hcc. If that is not possible ablation would give the best durable therapy for locoregional treatment of a small hcc. ...Read more
It produces a toxin: Aspergillus flavian produces aflatoxin, which is well-known to contribute to the development of liver cancer. The toxin is produced when grains or nuts contaminated with the fungus are stored improperly in moist conditions for a long time. Aflatoxin works together with hepatitis b in china and africa to raise the rate of liver cancer. It is not generally considered an important issue in the us. ...Read more
Good: Depending on the underlying liver disease, early stage hcc is curable. Unfortunately, the liklihood of additional tumors popping up in a diseased liver is also high. There are surveillance programs around the country and world for high risk patients. ...Read more
Not common: Fibrolamellar hcc is not common in people in their 20's. It is very rare. It is just that in the very unusual case that a young person gets hcc it is more likely to be the fibrolamellar type. There is no known way to protect specifically against the fibrolamellar but avoiding alcohol abuse and helatitis (b;c) with vaccination if needed, safe sex, and no IV drug use is the way to prevent hcc. ...Read more
Please tell me is there any cure or treatment for hepatocellular carcinoma and please guide me I am confused about it?
Depends: Depends on how advanced it is, my friend. Early hcc may be treated successfully, maybe even cured, with surgery but therapy for more advanced ones is directed mostly to shrink and control the cancer rather than curing it. It also depends on how healthy the patient is in general. Idealy should be managed in a multidisciplinary setting (surgeons, transplant specialists, gi, and medical oncologist). ...Read more
Possibly: People who are infected with hepatitis B virus (HBV) may develop a chronic infection that can lead to cirrhosis. The damage that results increases the risk of liver cancer (hepatocellular carcinoma). The risk is greater for people who have chronic HBV infection than for the general population and may be helped by vaccination. ...Read more
Alfa feto protein: Normally in the upper hundreds or thousands as I recall. ...Read more
Liver cancer: Heaptocellular carcinoma is a primary cancer of the liver. Hcc is most commonly associated with underlying liver disease, such as viral hepatitis, but can be associated with other conditions of the liver that cause scarring or cirrhosis. Although hcc can also occur in otherwise normal liver substance, this is rare (only 10% of cases). ...Read more
Fibrolamellar hepatocellular carcinoma has better prognosis than usual liver cancers. The diagnosis is made by examining the tissue by a pathologist. See this site for more info.
http://www. Ncbi. Nlm. Nih. Gov/pubmed/16475212. ...Read more
Used for Stage 4: Nexavar, or sorafenib, is used to treat advanced, unresectable hepatocellular carcinoma. It is also used to treat patients with advanced kidney cancer. This drug is a multikinase inhibitor and works by decreasing tumor growth and replication, by inhibiting the formation of blood vessels that tumors rely on to get nourishment. This is not a curative treatment, prolonging survival on average 7 mo. ...Read more
Hepatocellular carcinoma (HCC) is a Cancer arising from the Liver. It often occurs in in people who have a chronically damaged liver due to infection with Hepatitis B or hepatitis C Virus or it can be due to use of excessive alcoho, drinking that leads to Cirrhosis which then makes you more prone to ...Read more