Doctor insights on:
Medicine For Hemolytic Disease Of Newborn
Different blood type: Hemolytic disease of newborn is caused by different blood types in mom and baby. Classically, mom is rh negative (a- or o-, etc). The baby is rh positive. Mom then make rh antibodies that cross over to the baby and cause breakdown of the red blood cells. This can make the baby very sick. ...Read more
Test for mom/baby: The baby will get test like Coombs testing, hemoglobin or cbc, bilirubin tests and reticule yet counts. The Coombs tests shows that an antibody is cause the hemolysis. The antibody specificity can be determined by additional tests. These antibody levels can be measured in mom and baby. Most of these antibodies will cause hemolysis. Some can cause decreased RBC production in the baby. ...Read more
Jaundice and anemia: Hemolytic disease of the newborn (hdn) may develop when a mother and her unborn baby have different blood types. The mother produces substances called antibodies that attack the developing baby's red blood cells. The most common form of hdn is ABO incompatibility, which is usually not very severe. The least common form is rh incompatibility, which can be very severe, but can be prevented. ...Read more
HDN: During pregnancy, red blood cells from the unborn baby can cross into the mother's blood through the placenta. Hemolytic Disease of the Newborn occurs when the immune system of the mother sees a baby's red blood cells as foreign and produces antibodies against the baby's red blood cells. These antibodies attack the red blood cells in the baby's blood and cause them to break down too early. ...Read more
Various: Hemolytc disease can be mild and treated with bili lights. In extreme cases, it may be picked up early in pregnancy from an antibody screen. If positive, the antibody is identified. If a concerning antibodies present, the blood counts of the baby will be followed closely. Intrauterine transfusions may be required in these rare instances. ...Read more
A 10-day boy, was diagnosed of hemolytic disease of newborn when 4 and a half days. After treatment his icteric index is 10.3.Will the icterus recur?
Hemolysis: This would be dependent on the PRIMARY cause for the hemolysis ...Read more
Depends on form: Decades ago when I started rh hemolytic disease was often fatal during pregnancy & problamatic in newborns. Surviving infants often needed many exchange transfusions & had worrisome futures. Then a treatment called Rhogam came along & has ended that nightmare. In 26 yrs, I have transfused 1-2 ABO babies primarily for late stage anemia but had no fatalities. Rh disease is a problem without rx. ...Read more
HDN: The process of hemolytic disease of the newborn (HDN) starts soon after birth, however the symptoms (mainly jaundice) may not be detected if clinicians do not maintain a high index of suspicion. HDN due to Rh incompatibility is very rare in the US, but ABO incompatibility should be suspected whenever the mother has type O blood and the baby has either type A or B blood and there jaundice. ...Read more
ABO hemolysis: Hemolysis in newborns due to ABO incompatibility is not preventable, but is manageable under the care of an experienced pediatrician or neonatologist. For this reason, newborns from mothers with type O blood type or who are Rh- will be screened closely for this condition, as early recognition and intervention is key to successful recovery. ...Read more
If my 2nd son had hemolytic disease of the newborn, what are the chances the rest of my babies will as well?
Depends: Hemolytic disease of the newborn, which is due to rh or ABO incompatibility, happens when the newborn's blood type is incompatible with the mother's, and the mother has passed antibody to the baby in utero. In ABO disease, the mother must be type o and the baby either a or b. In rh disease, the mother must be rh- and the baby rh+. So, subsequent risk depends on the fetus' blood type. ...Read more
Yes: Hemolytic disease of the newborn, causing yellow skin and eyes (jaundice) with anemia, is most commonly due to a "set-up"--a blood type difference between mother and child. Blood types are caused by genes at the ABO and other loci (rhesus being most damaging), with o type or rh negative moms making antibodies to red blood cells of a or b or rh+ fetuses (if mom is o and fetus ab, baby switched), . ...Read more
Does the possibility of an unborn baby getting antibodies c&d, (hemolytic disease of the newborn) increase with each pregnancy?
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Yes. But only...: Mom would need to be rh negative. This would sensitize the mom, producing an anti-rh antibody that can cross the placenta and began to hemolyze the rh positive cells of the infant. This can began to occur early in the pregnancy, making the unborn child very sick. Or it can be detected at birth and cause prolonged jaundice. Subsequent children may be more affected. Mom needs rhogam. ...Read more
If mother has type o positive blood and newborn has a positive can it cause a crossover causing hemolysis or jaundice?
A to O set up: You do not need crossover to set up a problem of hemolysis if baby has this type. Mom's system can become sensitized in her lifetime to dietary products that will cause antibody formation to the blood type a, and this is usually only a problem after birth when the hemolysis and bilirubin disposal relies on babies system to keep the jaundice under control. Docs monitor and treat as needed. ...Read more
Group b infection:
Newborn can get group b strep infection either during passage through birth canal or after birth coming in contact with an adult carrier of this bacteria
the infection quickly spreads into the blood stream and can make the newborn really sick and has to be treated with IV antibiotics. ...Read more
Is it safe for me to give my frozen expressed breastmilk to a newborn of a friend who can't produce? I'm healthy with no disease or bad habits.
Possibly: There are quite a number of safety measures that human milk banks go through to make sure their donors are healthy enough to donate frozen expressed breast milk. I would advise you to contact your local children's hospital or a human milk bank and find out what screening they do before you attempt to donate milk. The handling of the milk is also crucial in preventing spoilage. Be safe first! ...Read more
Can you tell me how hdn (haemolytic disease of the newborn) illustrates incomplete penetrance, variable expression, genotype-environment interaction?
Homework?: Is this a homework question for a class you are taking? ...Read more
Genetic disease: Huntington's disease is inherited in autosomal dominant pattern. Even though it is a genetic defect, initial symptoms almost never present themselves in new born period. Earliest presentation of symptoms is at 20-30 yrs of age. Tremors, loss of co-ordination, seizures, dementia are clinical symptoms. It's a progressive disease which is usually fatal within 10-30 yrs of initial presenting symptoms. ...Read more
Blood cell disorders: It is the blood obtained from the cord, not the cord itself, that is being used to treat disease. Early, primitive cells, called stem cells, are used to treat many disorders of the blood, including aplastic and other anemias, leukemias, certain immunologic diseases, and even some metabolic disorders. Ongoing research includes non-blood diseases, such as stroke, diabetes, and even heart attacks. ...Read more
Sickle cell testing: In the United States, all states mandate testing for sickle cell anemia as part of their newborn screening programs. The test uses blood from the same blood samples used for other routine newborn screening tests. The test can show whether a newborn infant has sickle hemoglobin (from http://www. Nhlbi. Nih. Gov/health/health-topics/topics/sca/diagnosis. Html). ...Read more
Is there any alternative to surgery for spinal bifida? I have heard this disease is mostly found/prone to newborn child?
Can you tell me the genus and species of two gram positive pathogenic bacteria that are hemolytic and give the diseases t?
Can someone get a disease from a needle stick that caused them to bleed from a needle that was used while giving iron shots to newborn baby pigs?
Unlikely: But doubt that this has ever been the subject of a detailed scientific investigation. If you develop any suspicious symptoms would take this history with you to the doctor and be evaluated. Good luck. ...Read more
Will I get or spread any diseases to my newborn or older children from stepping on someone’s spit in? I put sanitizer on the ground & rubbed on soles
A few: One of the most common lung difficulties we see, especially with c-section babies, is transient tachypnea of the newborn. This occurs when there is still fluid in the lungs, because the baby didn't exit via the birth canal and literally have the fluid squeezed out. Infections can also occur resulting in pneumonia. Some babies "transition" slowly, & need a little help learning to breath room air. ...Read more
? necessary: Is it any of their business? If trying to explain it, suggest it is a breakup of blood cells in the blood stream. ...Read more
Depends: There are many different types of "neonatal autoimmune diseases" each with theire own time frames. Usually when someone is discussing neonatal autoimmune diseases they are talking about maternal antibodies that have passed through the placenta and are directed against antigens in the fetus and/or newborn child. ...Read more
Elevated liverenzyme: For liver enzymes to get elevated you need to have inflamation in the liver, so anything that does that can increase the liver enzymes including infections, congenital abnormalities. You should talk to the newborn's pediatrician for a clearer answer, as he/she will know ur newborn better.. ...Read more
Soon!: All states and the district of columbia screen for sickle cell disease as part of the newborn screen. The testing is very accurate and really doesn't need to be repeated if it is normal. If it is abnormal and confirmatory testing is desired it can an should be done promptly so appropriate treatment can be started as soon as possible. ...Read more
Confusing question: Newborns need to stay away from those known to have active contagious disease. Sickle cell is not contagious, and a healthy sickle cell patient need not be avoided any more than any other person. ...Read more