Doctor insights on:
Medicine For Hemoglobinopathies
Trait vs disease.: Hemoglobinopathies are a variety of inherited diseases where the hemoglobin molecule (part of RBC that attaches to o2 which all cells need to live) is malformed. Examples are sickle cell & thalassemia anemia. Abnormal gene from one parent, usually have 'trait' and live healthy life. Gene from each parent, get the disease: infection, stress, a cold, other events can set off a crisis and instability. ...Read more
Depends on disease: Thalassemia and sickle cell disease are the two most common hemoglobinopathies. They both have very different symptoms. Thal patients may have symptoms of anemia like feeling tired and some may need life long blood transfusions. Sickle patients may have pain crisis, infections, chest crisis, strokes, chronic organ damage. ...Read more
Various: These relate to hemoglobin, the molecule that helps transport oxygen, and is made of 4 subunits. Adults have 2alpha & 2beta, while kids have 2alpha & 2gamma. Other minor forms also exist. Any disorder that alters these subunits can lead to hemoglobinopathy, some of which have no significance (d and e) and others that may (thalassemia & sickle cell). ...Read more
Most so not: Most have altered hemoglobin in the form of "trait." Those individuals may only have small red cells but no anemia. However, patients who have full blown hemoglobinopathy are usually anemic. There are many forms of hemoglobinopathies... Such as thalassemia. Sickle cell disease vs trait is another type of altered hemoglobin. ...Read more
Hbg electrophoresis: The usual approach is to perform a hemoglobin electrophoresis. On occasion other more esoteric specific testing may be required depending on the patient's manifestations and family history of known type. You should be seeing a hematologist. ...Read more
Hereditary anemia: Thalassemia is a type of hemoglobinopathy. It is inherited from one or both of your parents. There are many kind of thalassemia. Most causes anemia (low red blood cell count). Anemia couod be severe requiring blood. Taking iron does not cure the disease. Thalassemia is common in people living in the mediteranian countries, africa, middle east, india, and sotheastern asia such as thailand, laos, et. ...Read more
What does it mean if I'm a carrier of beta chain-related hemoglobinopathy and spinal muscular atrophy?
Carrier status: SMA is an autosomal recessive neuromuscular disease To be a carrier means you have one 5q deletion on chromosome 5. Beta chain hemoglobinopathy means you have an altered beta chain of hemoglobin as seen in diseases such as sickle cell. Carrier status means you do not have disease but have ability to pass it on to offspring who will have disease if other parent is carrier and passes it on as well. ...Read more
A 4 month old's hemoglobinopathy test is indeterminate. Mother is fa and father is aa (both normal). Is the baby atrisk?
Not likely: This is a bit unusual. In a condition known as hereditary persistence of fetal hemoglobin (hpfe) there is an elevated amount of fetal hemoglobin present. This is reported as af, as there is always more HGB a than f present, unless you have thalassemia trait as well. If mom is not anemic, shouldn't be a problem. Not sure what testing was done to demonstrate that dad is aa rather than a/thal though. ...Read more
I have a hemoglobinopathy (not sickle cell or thalassemia). At what point is medication considered for my anemia?
Symptoms or severe: Depends on specific etiology, as treatments may vary significantly. Generally aggressive tx like transfusions are avoided except in emergencies, but other tx will be considered if there are sxs (like dizziness, weakness, shortness of breath) or if the blood level is low enough to cause other issues (e.g., high-output heart failure). Diet may be important as well in minimizing or avoiding meds. ...Read more
Drugs frm India safe: F from US asks: Are the drugs from India as safe as the drugs from the U.S? ANS: Some are some are not and some dangerous. I do not recommend them unless all else has failed. You don't want to be playing "You bet your Life" with them. ...Read more
Ambroxol is a…: Mucolytic agent, i.e., it makes mucus & sputum thinner & less viscous (sticky) & therefore more easily removed by coughing; so it is beneficial in diseases associated with increased mucus production (acute/chronic bronchitis, copd). It also appears to have anti-inflammatory properties. None of the articles I reviewed noted that this drug is not available in the us. Ask your fp/pharmacist. ...Read more
Urine testing is the: Most commonly used.Get a more detailed answer ›
Doubtful: Des has been off the market for decadesa and the structural anomalies are well defined. Talk them over with your doctor. ...Read more
A growing speciality: Anti aging medicine is really based around the goal of keeping individuals as healthy as possible. Not simply treating them when they are sick. This means paying particular attention to the current state of our health and how to make it better. Also look at less invasive ways of managing a person's health. It is fascinating. ...Read more
How can I increase my baby appetite, do I have to buy drug that increase my 1 year old baby appetite, he s active normal but I wish he eat more?
Depends: Depends on what type of IBS you have… Constipation type we have a few different medications, for diarrhea type there are fewer options. Before diagnosing yourself with IBS though, make sure you have colonoscopy and EGD and labs done and an examination as IBS is what we call a diagnosis of exclusion, where we "rule Out" other causes then call it IBS. ...Read more
For high BP: Eprosartan is used alone or in combination with other medications to treat high blood pressure. Eprosartan is in a class of medications called angiotensin ii receptor antagonists. It works by blocking the action of certain natural substances that tighten the blood vessels, allowing the blood to flow more smoothly. ...Read more
Seek Urgent Care: Take them to the emergency room.Get a more detailed answer ›
Please suggest the best OTC medicine (s) for sinus symptoms management (esp. The headache) and can be used regularly.
OTC meds for Sunuses:
Pseduephedrine (Sudafed) is the main decongestant sold OTC, but due to its potential for abuse, it is now stored behind the shelf and u need to ask for it. It can cause increased heart rate and insomnia.
u can use nasal sprays to decongest while avoiding the insomnia caused by oral decongestants. Anti allergy meds
can be used if they are adding to the congestion otherwise u can skip these ...Read more
Took statin drugs 9 years side effects made me stop the drug will the 9 years I was on statins be a credit when I get into my 70s and 80's?
Cholesterol karma: Lets start by saying statins simply control a risk factor (hypercholesterolemia). There is no evidence that they extend your life. The more important question would be, what are your current risk factors? Are you eating right? Exercising? What's your bmi. What's your blood pressure? What's your cholesterol now? Talk to your doc. They can assess your risks and set you on the right course if action. ...Read more
My sister committed suicide from a drug/alcohol overdose. I know it depends on the drug (s) & amount of alcohol. Would this been a painful death?
Usually not: People who have witnessed such deaths describe them as peaceful. I'm very sorry about your sister and whatever it was that caused her to decide life wasn't worth living. Our minds play tricks on us, and each of us has times when we are not ourselves. I hope you'll cherish the memories that you had together, and live your own life richly and well. ...Read more
I'm 38 I have plan to make a baby any medicine did I take to easy to pregnant me thank you and my husband he 's 47 yrs old so that's why I ask
Pregnancy: You need to know when you ovulate. If you have a 28 day cycle, you will ovulate on day 14 of the cycle. That is your prime time to get pregnant. To see how your ovarian reserve is, you need to have a fsh level drawn in your doctor's office. ...Read more
I'm confused, was diagnosed over year ago with spontaneous onj now in grade/stage 4a. Why do some dr. S only believe get it if u taken osteo drugs & etc?
Clarification….: Comment a little more on your question, please? I'd love to answer, but am not clear about your question. Were you diagnosed with onj without taking any medications and wonder why doctors are asking or assuming your history of bone-treating drug use? ...Read more