Doctor insights on:
Medicine For Drug Induced Lupus
There are major differences between what I call while lupus and drug-induced lupus. Basically these are illnesses with some similar manifestations and clinical manifestations. Some of the manifestations like rashes and joint pain can occur in both, but kidney involvement is notfound with drug-induced lupus. There are other differences also but this is one of the ...Read more
See below: Most common drugs involved in drug induced lupus are isoniazid, used to treat Rbc ;hydrazine, used to treat hypertension; and procainamide used In cardiology. Less common are sulfasalazine, quinidine, penicillamine, minocycline, methldopa, and chlorpromazine. Some of the current biologics have also been implicated. ...Read more
Yes: There are certain medications that cause lupus like illness this type of lupus is not like regular systemic lupus erythematosus. If you stop the drug that causes drug induced lupus the lupus usually resolves. Regular lupus has many manifestations not seen in regular lupus especially kidney involvement and neurological involvement. They also have different laboratory tests. ...Read more
Different types: The classic drugs are medications that are used for treatment of things like heart probelms (procanamide), blood pressure (hydralazine), seizures (dilantin), etc, but not everyone who uses these drugs get drug induced lupus. Recently some of the biologic drugs that are used to treat rheumatoid arthritis can cause a lupus liek syndrome. Usually stop the drug and the drug induced lupus resolves. ...Read more
There are about 30 o:
Common drugs include medications that are used less frequenty now:
Hydralazine - a blood pressure medication;
Isoniazid - an antituberculosis medication;
Procainamide - an anti arrhythmia drug
minocycline - an antibiotic
pyrazinamide - an anti tuberculosis drug
these are a few. A recent entry into the field are the biologics that are used to treat rheuamtoid arthritis. ...Read more
Search the web: Google the term and you will find the complete list. ...Read more
Drug side effect: Some medications can cause those who take them to develop symptoms that look exactly like lupus. Stopping the offending drug usually fixes the problem. ...Read more
Lupus like caused by: There are major differences between what I call while lupus and drug-induced lupus. Basically these are illnesses with some similar manifestations and clinical manifestations. Some of the manifestations like rashes and joint pain can occur in both, but kidney involvement is notfound with drug-induced lupus. There are other differences also but this is one of the main ones to discuss ...Read more
Within 6 mo.: Within six months or sooner.Get a more detailed answer ›
Very different: There are differences - especially less kidney involvement, different serology to name some things. It mostly resolves after stopping the drug involved. ...Read more
Three worth knowing: Isoniazid, Procainamide and Hydralazine are the three to remember. The latter two are largely superseded by newer medications. There's a bunch of others reported; http://www. Nlm. Nih. Gov/medlineplus/ency/article/000446.Htm gives a pretty good list, I had a case with phenytoin, and there's nothing magic about "38". New ones will appear over time. ...Read more
Much different!: First, your clinical sx are more important than the labs. Drug-induced sle is characterized by single-strand anti-da abs. Markers for possible pss include scl-70 and centromere antibodies. But where you on a drug which commonly caused drug-induced sle. What are your symptoms: fever, joint pain, pleuritis, pericarditis? Or do you have raynaud's, swallowing probs, etc. See a rheumatology expert! ...Read more
Should people diagnosed with sle or discoid lupus avoid taking the drugs associated with drug-induced lupus?
If possible: Certain drugs can affect lupus so if there is a choice it may be prudent to avoid three drugs however depending on your circumstance there may not be other options. If you must take a drug associated with lupus be vigilant in reporting any joint pains, fever, or unusual symptoms to your doctor. ...Read more
Are there any documented cases of drug induced Lupus caused by Aspirin and if so how long after discontinued do symptoms subside?
Do anti-histone antibodies appear exclusively in drug-induced lupus or can they appear in SLE & other disorders as well?
SLE: These antibodies are more common in drug induced lupus but occur in garden variety SLE as well. ...Read more
Not really: It can cause several different side effects but Lupus is not one of them ...Read more
Had drug induced lupus now resolved, still get very cold hands & feet etc I noticed today that now my fingertips are wrinkled from cold. Why is this?
? Raynauds: It may be raynauds disease especially if your hands blanch or turn blue with cold exposure. ...Read more
+ANA test. Elevated histones AB only. Only on aspirin and BB. Take some supplements in low doses like serrapeptase. Can this cause drug induced lupus?
Not known: I am not aware that this is associated with drug-induced lupus. Antihistone anybody's can be seen in wild or systemic lupus as well as drug-induced lupus. Certainly there is no evidence from what you tell us that you have lupus of any type. You say you're on aspirin and I'm uncertain why and you say are on BB and I don't know what that is. From the information you're giving us I'm not certain the information you're giving us I'm not even certain why they did it in a testing on you. From what I can tell you don't have Lucas from this conversation ...Read more
My doctor put me on minocin (minocycline) for my acne but I'm nervous of side effects and drug induced lupus. Are these very rare? I've been on this drug years ago.
Good choice: Acne is a serious, chronic disease that is a major personal and professional liability. Minocycline very seldom causes problems and when it does, discontinuing the medicine and replacing it with something else is easy and you'll heal up fine. Nothing worthwhile in life is risk-free. ...Read more
3 years ago I had drug-induced lupus but I still feel very unwell: severe pain, fatigue, cold sensitivity, swollen glands & more regularly. What to do?
Drug-induced lupus: See a rheumatologist and get fully evaluated. This may or may not be related to the former drug-induced condition but certainly deserves a thorough assessment. Good luck. ...Read more
Could Humira (adalimumab) cause drug-induced lupus on the head? Some small lesions on the head. (Rheumatoid arthritis)
Can help more often: Chemotherapy can help treat lupus but certain drugs may provoke lupus. Most of the drug induced lupus cases are not wild lupus as these are actually a different type of lupus we call "drug induced lupus".Although unusual certain chemotherapeutic agents have a potential to cause drug induced lupus ...Read more
Not Fair: Every person is a different element that we have to figure out what works best for your body. You might have to try a few different medications before you find which works best for you! Don't give up after just one med doesn't work. What works for one patient might not for another with the same condition. It's what makes us unique and what makes being a doctor so confusing. ...Read more
A drug court judge ordered me to stop taking my prescription meds4my lupus. He says they mess with my drug testing. Is this legal? What do I do?
See below: This is tough. If you have had a demonstrated issue with a substance, it may be reasonable to Prohibit it even if there is a potential benefit. However, if the prescribing doc acknowledges in a letter that he is aware of a problem, you may be able to stay on your meds. Be careful. Despite your perceived medical benefit, the meds may still be causing more harm than good. ...Read more
I have lupus will taking atripla as pep for 28 days have negative effects on my body or on the effectiveness of the drug?
Why would it?: I presume that you are taking atripla to treat your condition and thus don't understand why using a drug to control your disease condition would hurt your body (unless you are allergic or intolerant to one of the ingredients). It has nothing to do with your lupus. ...Read more
Is sulfasalazine considered a sulfa drug? Why would my rheumatologist prescribe it for me when I have lupus?
It does not treat: Lupus! Check what it is used for on the web. Talk to your doctor, you possibly may have been misunderstood! ...Read more
What the point to biopsey I have lupus, why do I have to have a biopsey. My blood levels have been adnormale for 4 months. I want to take all these new drug treatment for lupus other then predison.
Mild lupus-no pred!: Most of my patients with systemic lupus respond quite well to Plaquenil (hydroxychloroquine) and ridaura (oral gold). Imuran also works well, as does methotrexate. All are not "new" drugs, which the vast majority do not need! Prednisone is used for severe systemic issues in high doses, or small doses for rescue therapy. ...Read more
Aside from Plaquenil, (hydroxychloroquine) which drug used to treat lupus has the least side effects? Likely going to have to add another to my cocktail.
Depends: Every lupus patient is different. Choice of meds depends on the severity of your illness. Work with your rheumatologist to develop the most appropriate treatment plan for your case. That's his job. ...Read more
What drugs do I use for lumps n discolouration and bald patches when diagnosed with discoid lupus? Am on methyl predisolone at the moment n not working
Chronic changes: Discoid lupus can heal but it can take a long time - weeks to months because the skin has been injured. It is hard to be patient. Talk to your dermatologist about topical medications and oral medications to help bring your skin condition under control. Steroid injections into the skin are also helpful. ...Read more
How might you treat leaky gut syndrome with a patient who has lupus, fibromyalgia, and allergic to sulfa drugs and (90/100 foods). Thank you.
Start with delayed: food allergy panel (Elisa Antigen testing) to see the whole spectrum of foods/environmental allergens that you are exposed to perhaps unknowingly. So you can begin to do an elimination diet to help repair your gut lining. This would be a start. Then work with an integrative doctor, who can monitor your progress, and medically manage you through this. Correcting your diet is the first step. ...Read more
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