Doctor insights on:
Medicine For Dornase Alfa Allergy
Thick chest mucus: Dornase alfa, called pulmozyme, (dornase alfa) is a medicine that makes lung mucus thinner and easier to cough up. It was developed for patients with cystic fibrosis and is used every day for months or years. It is not used for short-term colds or bronchitis. It gets into the lungs by breathing in a mist of the medicine from a nebulizer machine. Treatments usually take 10-20 minutes. ...Read more
Allergies occur when your immune system is triggered by envirionmental factors it should ignore--for example, pollen in the air, or dander on a cat or dog--and creates cells to fight against them. An allergic reaction typically causes itching, congestion, or drainage, and ...Read more
My sister makes herself throw up when she does her pulmozyme (dornase alfa). What can I do to help her?
Mgt/CF: Some secretions can be swallowed and this can cause irritation of the stomach lining. She should speak with her PCP about the use of an antacid, following the Pulmozyme (dornase alfa) with nebulized saline to clear the secretions. Chest physiotherapy is an important part of her management. Does she wear a vest for CPT? A virtual consultation to review chest clearance and her medications can be booked online. ...Read more
In the refrigerator: There should be specific instructions when you get a new prescription as to where to store it (what temperature and for how long), and whether light damages it. There should also be an expiration date to tell you when it will no longer work if you keep it too long. Don't use it afterthat date. If you have questions, ask your pharmacist or go to the web site shown in the package insert. ...Read more
Thinning mucus: Dornase alfa, called "pulmozyme", breaks down dna which is part of the material in thck chest mucus in patients with chronic lung disease such as cystic fibrosis. The medicine thins the mucus and makes it easier to cough out. It is used every day for months or years and gets into the lungs by inhaling the medicine in a mist. Treatments take 10-20 minutes. It's not used for colds or bronchitis. ...Read more
Could pulmozyme (dornase alfa) use result in increased respiratory rate in non-cf patient with a tracheostomy?
Maybe: Side effects with Pulmozyme (dornase alfa) are various and can include irritation of the throat, nose and voice changes. It can also cause hoarseness. I use a fair amount in my patients and have not seen it increase respiratory rate. I guess if it was irritating the airway you could breath faster due to pain/discomfort. I don't think that increased resp rate is very common on this drug. ...Read more
Intranasal steroids: In milder cases of allergy, otc antihistamines such as claritin, allergra and zyrtec can be used. The most effective medications for more severe cases are nasal steroids such as flonase (now generic), nasonex, (mometasone) Omnaris which are liquid sprays, and Qnasl and zetonna which are dry. Head to head studies show that nasal steroids (vs antihistamines)are much better for congestion and allergy symptoms. Vers. ...Read more
Treating congestion: Cold/allergies are usually a very vague and general term to descibe of nasal congestion, runny nose, cough due to post nasal drip and headache if there are sinus infections. Depending what causes it and how severe your symptoms are, best treatment can be different. If you can be more specific, it would be helpful. Otherwise, you should see a doctor to be evaluated to see which treatment is best. ...Read more
No single one:
Depending on the severity of your condition.
There is no one best drug for anyone but most people respond well to intranasal cortisone + a intranasal antihistamine. Dymista is currently the only rx drug with this combination.
Avoidance remains the best and consider allergy shots if your symptoms are not adequately controlled. However allergy shots are not medicine. ...Read more
Rash and anaphylaxis: The most common allergic reaction to a drug is a rash. In severe cases this is accompanied by breathing trouble and could even be life-threatening anaphylaxis. Stomach upset is a common side effect and is not likely to be a true allergy. However, it is still important to let your doctor know this. ...Read more
It depends: Strictly for allergy you have the antihistamines that are divided into sedating and non-sedating. The sedating are a heterogeneous group, the commonest side effect is sedation. They can also cause dry mouth and constipation. The non-sedating have generally few side effects. The decongestants (pseudoephedrine, phenylephrine) in combinations and alone cause palpitations, restlessness and increase bp. ...Read more
Medicine allergy: Many people also were falsely labeled allergic to penicillins during childhood. Viral infections are the most common cause of rashes in children. If an antibiotic is given 1-2 days before the rash from the virus would start, your parents are told to stop the medicine because of allergy to the medicine. If this sounds familiar, allergy tests are available to clear these medications off your list. ...Read more
Reactions to a drug: A drug allergy occurs when a person is sensitive to a medicine. Signs of allergy can include itching, rashes, breathing problems and even life threatening problems like low blood pressure and anaphylaxis. Hepatitis can occur with severe drug allergies. It is imperative to stop the drug causing the allergy. ...Read more
No: Most allergy medicine are safe and effective for long term use. Allergies are chronic conditions. See an allergist for evaluation to determine if allergy injections would be appropriate. ...Read more
Most effective med: The most effective medication for seasonal allergies is topical nasal steroid sprays such as qnasl, flonase, nasonex, (mometasone) rhinocort, nasacort, etc. Antihistamines are pretty good for mild symptoms of itching, sneezing, runny nose, but less effective for nasal congestion or stuffiness. Best effect if nasal spray started before symptoms start! ...Read more
Many to choose from: The most effective treatment for nasal allergies is the topical nasal steroid sprays (qnasl, flonase, nasonex, (mometasone) etc)--they are available by prescription. For over the counter allergy medications, new generation antihistamines such as claritin, zyrtec, and Allegra are helpful. These also come with the decongestant that is sudafed. The best long term treatment for allergies is allergy shots! ...Read more
Depends: The most frequently used and most available without a prescription are antihistamines. The new generation ones (zyrtec, claritin, allegra, xyzal, (levocetirizine) clarinex) are safe and effective. The most effective treatments for allergic rhinitis are nasal steroid sprays. The strongest allergy medication would likely be considered oral steroids like prednisone, but the significant side effects limit is use. ...Read more
Where are symptoms?: Usually nasal. I'd start with an otc anti-histamine like tavist (clemestidine). ...Read more
Sometimes. Depends.: Sure. Sometimes. Not always. Antihistamines don't help colds (eh, we all try'em) but decongestants do (help stuffy head, nose etc). Steroid nose sprays? Monsters on hay fever, & help nasal polyps (often w/o allergies); bupkis on non-allergic noses (non-allergic rhinitis). Enigma: Those same non-allergic noses respond to antihistamine nose sprays (azelastine). ...Read more
Antihistamines: You can take oral antihistamines for temporary relief, you need to wear gloves before you clean their cage, don't handle them and find them another home. ...Read more
Tricky: Medication reactions can be tricky as the type of reaction can be intolerance vs allergic. Avoidance is the best treatment for a drug allergy and using a suitable alternative. In a life threatening circumstance, desensitization by an allergist in the hospital is an option. Sometimes drug allergy can resolve over time such as penicillin. An allergist can assist in a good long term plan. ...Read more
See an allergist: You will need to see an allergist. They will determine if you are truly allergic. If you are an you need the medication there are protocols that can be used to desensitize you. Most of the time this is not necessary as alternative agents are usually available. ...Read more