Doctor insights on:
Medicine For Dermatosclerosis
Bad disease: Scleroderma is a progressive disease that affects the skin and connective tissue (including cartilage, bone, fat, and the tissue that supports the nerves and blood vessels throughout the body). There are two major forms of the disorder. One localize and could effect the whole body. ...Read more
Thickened skin: It is a thickening of the skin usually on the upper back and back of the neck. More common in diabetics and heavier people. Treatment is difficult as medicine is partially effective in preventing progression of problem. ...Read more
I try to avoid toxic drugs and treatments. What can I try before I go for traditional medical care for circumscribed scleroderma?
NOT AS SEVERE: Scleroderma is a fascinating disease and has 3 main types, diffuse, limited and localized also known as morphea. Diffuse scleroderma is the most severe. Circumscribed scleroderma or morphea tends to mean a localized area of thickened skin. This tends to be less severe with few compications of other organs which is typical of diffuse scleroderma. Treament is limited. ...Read more
Much different!: First, your clinical sx are more important than the labs. Drug-induced sle is characterized by single-strand anti-da abs. Markers for possible pss include scl-70 and centromere antibodies. But where you on a drug which commonly caused drug-induced sle. What are your symptoms: fever, joint pain, pleuritis, pericarditis? Or do you have raynaud's, swallowing probs, etc. See a rheumatology expert! ...Read more
Hi, can I close les 3mmhg to 20mmhg with strict diet, medicines and rehabilitation withnout fundopli? I have GERD and dysmotility but not scleroderma.
Diet: avoid fatty foods, chocolate, peppermint, licorice, coffee, alcohol, tobacco. Do not go to bed with a full stomach.
Medications: proton pump inhibitors like Omeprazole will help alleviate symptoms but do not affect les pressure. Not sure if Cisapride is available in your country but this could be helpful. ...Read more
Hard skin: Scleroderma literally means "hard skin." it is a connective tissue disease that primarily involves the skin which becomes fibrotic (hardened). Changes also may occur in the blood vessels, muscles, and internal organs. The disease involves autoimmunity whereby the immune system attacks the normal tissues of the body. The cause is unknown. ...Read more
I hate: As a surgeon to get involved but i lost my wife in just two years... It is an autoimmune disease of unknown origin. When just suspected a sedimentation rate, ANA levels, anti scl-70 and anti-centromere antibodies should be stat done. A good resource is this web site: http://www.Synnovation.Com/sclerodermafaq.Html i would seek help from a university based rheumatology department... ...Read more
Depends on type: The treatment ranges from "no treatment necessary" for mild forms of localized scleroderma (limited to the skin) to bone marrow transplantation for systemic sclerosis with internal organ involvement. Though there is no cure, advances are being made in the treatment of all manifestations of the condition. ...Read more
The diagnosis of scleroderma is based mostly on signs and symptoms. Lab tests may help confirm the diagnosis and even
offer some predictions as to risks of certain types of complications. Anti rna-polymerase iii antibody, increases
risk of renal crisis and sudden increase in blood pressure, antitopoisomerase ab, increases risk for scaring of the lung, anticentromere ab, pulmonary hypertension. ...Read more
Large range: There are numerous manifestations of scleroderma but the main feature is usually hard skin. This may be thickened hard skin in patches or around just a few fingers +/or toes or around the mouth. Others may have greater involvement of arms, legs causing difficulty moving joints. Worst are disfigurement of face and widespread tight skin over chest, abdomen. ...Read more
Autoimmune disease : Scleroderma literally means, "hard skin" which is a prominent feature. It is an autoimmune disease that results from cells making excess collagen which hardens and tightens the skin and blood vessels and sometimes internal organs. The severity can vary greatly from person to person. Fortunately, it is a rare disease. A rheumatologist is the best doctor to evaluate and treat this disease. ...Read more
Skin changes: The first sign is usually patchy areas on the skin that often make a linear pattern. Early on, they are slightly pink and thickened, but can be flat and shiny. As time passes, the skin spots enlarge and often become thick and lavender/purple-colored, sometimes with pale flat centers. Scleroderma can also affect the heart, lung, kidney, joints, digestive tract. Please see your doctor if you're worried. ...Read more