Doctor insights on:
Medicine For Copaxone Allergy
What are the side effects for taking oral MS drugs as opposed to copaxone (glatiramer) and all the other injectable drugs.
Complex : All ms drugs have potential side effects, and Copaxone has injection site reactions, lipoatrophy, an occasional chest/flushing reaction, and of course, the need to inject. All three orals are well tolerated in most folks, but tecfidera may cause severe nausea, diarrhea. Better tolerated might be Gilenya (fingolimod) or aubagio. Talk to neurologist about your best approach. ...Read moreSee 1 more doctor answer
Allergies occur when your immune system is triggered by envirionmental factors it should ignore--for example, pollen in the air, or dander on a cat or dog--and creates cells to fight against them. An allergic reaction typically causes itching, congestion, or drainage, and ...Read more
I am ending using copaxone (glatiramer) after more than two years. I am going to try bd 12 (not yet available to australians). Should there be a waiting period before starting a new drug?
NMO: In the old days, we thought that nmo was a variant of ms. Now we realize that it is very different, although may present the same way. Because it is so rare, there will never be enough people in an fda trial to approve a drug therapy. I have had success with rituxan (rituximab). Two men in this country are the leading experts on the topic, dean wingerchuck at mayo clinic and ben greenberg at utsw. ...Read more
# OF INJECTIONS: Both Avonex and Copaxone are drugs of the 90's, and have helped numerous pts. Copaxone is injected daily, does have injection rxtns, yet is considered safer for pregnancy. Avonex is injected once weekly, but can cause flu rxtns, depression, thyroid and liver issues, and is not safe for pregnancy. Both are modestly effective, but many newer agents have better outcomes (tysabri, gilenya, (fingolimod) etc). ...Read more
Avonex (interferon beta 1a) v Copaxone: Avonex (interferon beta 1a) is an injection given to a muscle once per week. It is a deep shot. Copaxone is a superficial shot given under the skin every day. The retail costs of the medicines are about the same. They are both expensive; insurance coverage may be important. Avonex (interferon beta 1a) sometimes may cause flu-like side effect symptoms, copaxone may not. Both can cause irritation by the injection site. ...Read moreSee 1 more doctor answer
See answer below: Both are used in rrms with similar efficacy levels. Copaxone (glatiramer) does not need blood monitoring and is administered as a subcutaneous sc injection daily. Side effects include injection site reactions. Interferons need lab work monitoring, can be a weekly injection into a muscle (avonex), every other day sc (betaseron) or three times a week sc (rebif). Most commo side effects include flu-like symptoms. ...Read more
Some control: Decrease relapses about 29%, forestalls disability, and may prevent MRI lesions. Works by controlling inflammatory lymphocyte attack on brain and spinal cord. Is a modestly potent medication, and works more effectively in the newer 40 mg TIW formulation. ...Read moreSee 1 more doctor answer
Somewhat: Copaxone is seemingly the most used drug for ms, but likely intermediate in efficacy. We use relapse rate reduction c/w placebo, as one measure, and Copaxone has been shown consistently to have a 29% rrr. This is about the range for betaseron, and rebif. Contrast to tysabri, (natalizumab) about 68%, Gilenya 54%, and a promising drug bg-12, 44-53%. The choice of a med should also consider risk. ...Read more
Variable: Copaxone (glatiramer) is a first line agent which may not be useful for many pts, and may take up to 4-6 months to reach maximal potency in some pts. If relapses continue to occur, and your MRI shows active lesions, other meds may be better choices for you. Discuss thoroughly with your neurologist. ...Read more
What do you suggest if my child has lost her job and we will not be able to afford her next shipment of copaxone, (glatiramer) what do we do?
What's the most effective medication for secondary progressive multiple sclerosis? My dr has me on copaxone (glatiramer) for almost a year now and it's not helping
Multiple sclerosis: With the exception of Novantrone (mitoxantrone) and steroids there is no other approved therapy for secondary progressive ms. The new oral therapies and old injectable platform therapies are only effective in relapsing ms (slow down number of relapses over time) not effective in progressive ms. Physical therapy, ampyra, (dalfampridine) muscle relaxer and other medications could be used to improve symptoms of ms. ...Read moreSee 1 more doctor answer
VERY DIFFERENT: Entirely different chemical classes, with distinct different mechanisms of action, and outcome data. Both seem safe, Copaxone (glatiramer) tho is injected daily, causes lipoatrophy, hypertension, and injection reactions. Tecfidera may be tough to tolerate due to flushing, nausea, diarrhea, stomach pain. Copaxone (glatiramer) relapse reduction is 29%, but tecfidera, drops 44-52%, oral twice daily, no needles. Talk to doc. ...Read more
In lady patients with ms, should they stop taking copaxone (glatiramer) when trying to get pregnant?
PERTAINENT QUESTION: Likely, Copaxone (glatiramer) safe, as fda considers it a category b drug, but, usually, i suggest holding it for a while before conception, just to be extra cautious. Also, pregancy is clearly protective, and being off the Copaxone (glatiramer) is not risky then. After labor and delivery, i restart within 48 hrs, as we need to prevent post-partum relapses, which can occur about 6-8 weeks after baby arrives. ...Read more
I have started my medication in june (which is an injection of copaxone (glatiramer) everyday) I have yet to get my period?
Unusual reaction: Copaxone (glatiramer) does NOT usually affect hormonal function, and need to have your gynecologist assess this. Sounds like a co-morbidity rather than a direct relationship, but unique reactions can and do occur. If no explanation otherwise, perhaps not a bad idea to try a different disease modifying agent. ...Read more
Can I take plaquenil 400 and Gilenya (fingolimod) 0.5 together? I was on copaxone and it wasn't working so I got switched to Gilenya (fingolimod).
Drug interactions : No significant interactions reported in literatureGet a more detailed answer ›
My daughter has lost her job and we will not be able to afford her next shipment of copaxone, (glatiramer) Any OTC medications she can take instead?
Contact prescriber: Copaxone (glatiramer) is a specific combination of biologic agents used for treating MS (L-alanine, L-Lysine, L-glutamic acid and L-Tyrosine) . Try discussing with her prescribing doctor - there may be a way to get a short supply of her meds at a discounted price for a while. ...Read more