Doctor insights on:
Medicine For Congenital Hemolytic Anemia
Can you be more....: Specific? I'm not sure which congenital hemolytic anemia you are speaking of. There are many causes of hemolysis from intrinsic red cell abnormalities. They are generally subdivided into hemoglobinopathies, membranopathies and enzymopathies. Their mechanisms of red cell compromise are different, as is treatment. Our hematology grop at primary children's in slc is xlnt and always here to help. ...Read more
Can blackstrap molasses make you feel better if you have drug-induced hemolytic anemia but your iron panel (ferritin, tibc, tsi, si) were all normal?
Forgive my candor: Blackstrap molasses is an antique health fraud which despite what others may tell contains only small amounts of vitamins, and acquires most of its mineral content from the machinery in which it was processed. Hemolytic anemia -- drug-induced or not -- is serious and needs to be followed up by a physician. Iron won't touch it. Don't let others play you for a sucker. ...Read more
My father, age 70. Was diagnosised acute hemolytic anemia, after taking hormone medicine, his ntuh has raised from 6 to11, but glucose went up to 10?
Possibly: Hemolytic anemia may have numerous causes including toxins, infections, genetic diseases, autoimmune diseases, drugs, certain types of food, etc. So theoretically if you know what the cause is then it can be avoided. Therefore an adequate diagnostic workup by your doctor is necessary. ...Read more
No: It can be due to an underlying autoimmune disorder, such as lupus or rheumatoid arthritis. In this case, the underlying autoimmune disorder may be hereditary; but the autoimmune hemolytic anemia is not hereditary. It is simply the manifestation of the underlying disorder. There are also several causes of autoimmune hemolytic anemia that are not inherited. ...Read more
Stopping dapsone: The best way to treat Dapsone related anemia is by discontinuing dapsone. Dapsone causes hemolytic anemia which is dose-dependent and can be stopped only with discontinuing the drug. Usual practice is to use the lowest possible doses of Dapsone and support with vitamin E and folic acid. ...Read more
Find the cause: You have to find the cause of why the red blood cells are being destroyed (hemolysed) then target it; certains cause of hemolysis are medication, heredity, malignancy, infection, enlarged slpeen etc... ...Read more
Yes: You have to figure out why you are bleeding into your stomach and if there are any other places where you are bleeding and why and if you are making sufficient replacement blood and if not why not. This can be orchestrated, at least at first by your doc, and if things get really messy by a hematologist. Good luck! ...Read more
Uncommon.: This would be very uncommon. But it can happen. Definitely take the prescribed medicine and follow up with your doctor regularly. ...Read more
Cell membrane damage: Pyruvate a kinase deficiency results in reduced ability of red cells to make ATP -the "energy source" of cells. Atp is also necessary to protect cells from damaging compounds such as free radicals. With decreased energy supply the cell is not able to maintain appropriate concentrations of electrolytes and fluids, becomes distorted or stiff, and then is destroyed in the spleen or liver. ...Read more
Multifactoral: Coombs (-) hemolytic anemia means that you have evidence of hemolysis (RBC fragmentation) that is not immune mediated. Potential causes include medications, artificial valves, microangiopathic causes, and disorders involving the RBC membrane, etc. Large granular lymphocytosis may be reactive or represent a leukemia if absolute levels are 2-20, 000 and sustained for >6 mo in your peripheral blood. ...Read more
? necessary: Is it any of their business? If trying to explain it, suggest it is a breakup of blood cells in the blood stream. ...Read more
RBC breakdown: Hemolytic anemia is where red blood cells are destroyed too quickly. There are many possibilities that would cause this rbc breakdown. Antibodies, abnormal rbc membranes (spherocytosis), abnormal hemoglobins (sickle cell, thalassemia), abnormal rbc enzymes. If hemolytic anemia is is suspected, many tests may be ordered to determine the cause. ...Read more
Cause of hemolysis: Once hemolysis is thought to be occurring, the cause is saught. The causes are many. Some are inherent to the red blood cell (sickle cell, spherocytosis, thalassemia, g6pd deficiency). Some are from antibodies. Some are from other causes of destruction within the blood vessels (mechanical heart valves, hemolytic uremic syndrome). This work up is quite involved. ...Read more
Autoimmune reaction: Cephalosporins interact with red blood cell membranes. The body can sometimes produce antibodies against cephalosporins that also interact with the surface of red blood cells. These antibodies thus activate the body's immune system to attack its own red blood cells, causing hemolytic anemia. This is a rare but severe side effect of cephalosporins. ...Read more
Yes: Malaria symptoms show up a week to a few months after being infected by a mosquito bite. With treatment, the symptoms should go away in a couple of weeks. However, without treatment, and depending on the strain of malaria parasite, an infected person can have symptoms for a few years, up to a few decades. The person develops immunity over time, and his symptoms may decrease as the years go by. ...Read more
No: The oxygen carrying capacity of your blood, which is what anemia affects, does not affect fertility. However, depending upon how profound your anemia, it may make the pregnancy very difficult and risky. I would definitely correct the anemia before conception and remain in the care of your hematologist to maintain normal hemoglobin levels throughout your pregnancy. ...Read more
Haemoglobin is not found in the urine of a healthy person but is in a person with hemolytic anemia, is this true?
It's not so simple: Everyone has a little bit of blood in the urine. A runner usually has mild hematuria from the mechanics of running with a full bladder. Further, someone who has hemolysis that's not intravascular (i.e., autoimmune hemolysis, spherocytosis) won't spill hemoglobin, and somone with mild ongoing hemolysis (sickle cell) with enough haptoglobin to trap the hemoglobin won't spill it either. ...Read more