Doctor insights on:
Medicine For Chronic Leukemia
What are pros cons of drug procrit (epoetin alfa) to treat 88 year-old man whose chronic leukemia is now becoming acute where he needs transfusions every two weeks?
Limited value: Procrit (epoetin alfa) is commonly used in patients with cancer. But it is not always effective as it helps to raise red cell counts (hb) in most pateints but takes 4-6 weeks before it has any visible benefit. A patient with acute leukemia has more urgent needs which are best met with a blood transfusion as needed. But his age is against him to achieve much benefit from anything further that can be done for him. ...Read more
A malignant hematologic neoplasm that originates in the bone marrow and represents a clonal proliferation of hematopoietic elements belonging to any of the myeloid, lymphoid, erythroid, and megakaryocytic lineages. Of note, other hematologic neoplasms like lymphoma or myeloma may demonstrate a leukemic phase without actually originating in the bone marrow ...Read more
Blood work etc: You would need at least- blood work. Imaging scan for abdomen would be needed in certain chronic leukemia (cml) to evaluate spleen or if there is other indication (such as presence of abdominal pain etc); a bone marrow biopsy will be needed in certain case of chronic leukemia. Please discuss further in detail with your hematologist/ oncologist. Read more at www.Cancer.Net ; www. Lls. Org. ...Read more
Wish I knew.: There is some evidence that excessive exposure to chemicals such as benzene may lead to an increased incidence of chronic myeloid leukemia, and excessive exposure to radiation has also been implicated. Cllhas been linked to pesticide exposure in some-but not all-studies. In animals, diseases like cll are usually caused by a virus. In practice a doctor rarely finds the cause of a patients leukemia. ...Read more
50% are asymptomatic: About half of patients with chronic leukemia have no symptoms and are discovered on a routine CBC (complete blood count) usually obtained for some other reason. When symptoms do occur, they may include fatigue or tiredness, swollen glands or lymph nodes, low grade fever or sweats that are persistent. More advanced symptoms can include, bleeding, bruising, anemia, enlarging belly or an infection. ...Read more
Visit med onc doctor: The best approach is to meet with a medical oncologist with experience and discuss the treatment options when the diagnosis is confirmed. There are specifical mutations that can be tested for to guide the therapy. It depends if you have CLL or CML type. The oncologist can order the genetic testing and discuss current treatment guidelines. Then you give treatment a shot and see how it works. ...Read more
Chronic leukemia: 2 big groups of chronic leukemia are- chronic myeloid leukemia (CML) and chronic lymphocytic leukemia (cll). The chance of beating CML is very good as the response to daily tyrosine kinase inhibitor therapy is amazing and the remission rate is high. In cll, however, therapy usually won't be needed on diagnosis if there is no indication. Also, many times people die of something else and not due to cll. ...Read more
Various: Acute leukemia can lead to symptoms (bleeding, fever, infection, weakness) very quickly and requires treatment soon to avoid serious consequences including death. Chronic leukemias are more indolent may take awhile before causing symptoms often diagnose incidentally on a blood count. Treatment depends on the kind of leukemia: myeloid-treated soon to avoid becoming acute; lymphoid-could be watched. ...Read more
Everything: Acute leukemia is presented with the presence of significant level of a very immature blood cells in the circulation and increase level in the bone marrow. It is a very agressive and life threatening. Without treatment people die within weeks and few months only. Chronic leukemia- is progressing slower than acute leukemia. Chronic leukemia can transform into acute leukemia sometimes. ...Read more
Curability: Acute leukemias typically need treatment right away and can possibly be cured. Chronic leukemias are not usually curable because they are typically slower growing. I tell patients chronic leukemias are treatable not curable. Hope this helps. ...Read more
Varies: Majority cases are asymptomatic and the evaluation is started due to abnormal blood work. When the leukemia is more advanced - patient can become symptomatic-and can be presented with-anemia, low platelet level- bleeding, increase white blood counts, recurrent infections, fatigue/decrease energy level, fever/chils/night sweats, increase abdominal girth etc. Read more : www.Cancer.Net / www. Lls. Org. ...Read more
ONLY IN CLL: Chronic leukemia is two main types. Chronic lymphocytic leukemia most of the times do not need treatment and yes, counts may stay high. Chronic myelogenous leukemia always need treatment and counts should normalize with treatment. ...Read more
Cell are abnormal: Leukemia is a cancer of blood and bone marrow. These cells are not normal and are not found in normal blood and marrow. Usually there is some type of dna damage in these cells that causes the cancer. Eventually leukemia will destroy the bone marrow, making it impossible to make normal blood cells. That is the key feature, it's progressive, destructive and eventually fatal if not treated. ...Read more
Nature: Acute means urgent require treatment right away. Chronic likely present fora while and may not require treatment urgently. ...Read more
More info needed: There are several types of chronic leukemia. Can you be more specific in what you would like to know? ...Read more
Depends on type.: The most common chronic leukemia is chronic lymphocytic leukemia (cll). With initial treatment with the most aggressive treatments, such as fcr have a response rate of 95% and complete remission rate of 70%. Chronic myeloid leukemia (CML) has a 95% rate of complete cytogenetic response for chronic phase patients receiving initial therapy with the latest drugs. ...Read more
I'm just wondering, if you are diagnosed with a form of chronic leukemia can it change to an acute leukemia?
Yes, sometimes: There are two separate types of chronic leukemia;these go by the names CML and cll. They follow a separate course and can have a long course of disease. CML often ends up as acute leukemia (called blastic change which is a type of acute leukemia bearing poor survival once this transformation has taken place. Fortunately the risk of this happening is much reduced with the modern treatments for cml. ...Read more
How long it will will take for acute and chronic leukemia to develop in the body before they can be found on cbc or show symptoms,,,, months or years?
It is not feasible to say, for a normal person, how long it will take for the person to develop leukemia. Vast majority of the people never get one.
For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Drink enough water daily, so that your urine is mostly colorless. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form.
Practice safe sex, if you have sex. ...Read more
How can I decrease my husband's high white blood count? He has chronic leukemia & his white count is getting higher. Is there anything we can do?
Somewhat: Patients with chronic leukemia are twice as likely as the general population to develop other malignancies, including breast cancer. This likely has to do with chronic leukemia patients having a genetic predisposition, compromised immune systems, or just generally being older. ...Read more
I have a friend with lymphocytic chronic leukemia. What are the best superfoods to help with immune system and chemotherapy?
Organ meat: CoQ10 is found naturally in organ meat (heart liver kidney) and can help restore antioxidant balance while taking chemotherapy. That is the least obvious source if you Google "superfoods". Rooibos tea is a good antioxidant. Fruits, vegetables and nuts considered to be super-foods are listed all over the internet. Now if you return to Health Tap later today there will be many more responses! ...Read more
Can wbc count in chronic leukemia spontaneously return to normal range. I was at 18, now 9. W/out treatment? Possible?
Hematologist: You haven't provided enough information but spontaneous remission is rare but possible. A hematologist who knows your case and diagnosis is best qualified to answer your question. ...Read more
Can they do a bone marrow biopsy even if the platelets seem fine but their is signs and symptoms of chronic leukemia?
What is success rate of using prednisone in treatment of 88 year-old man whose chronic leukemia is now becoming acute with transfusions every 2 weeks?
Not significant: I am sorry, but I don't think that by itself will work. I do not know what is the reason to give you Prednisone for acute leukemia. If that is given in conjunction to other kind of therapy-that would make more sense. Please discuss with your oncologist further. Dacogen (decitabine) is something you can consider ...Read more