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Doctor insights on: Medicine For Biliary Atresia

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Is biliary atresia hereditary?

No: There is no proof that it is hereditary. Fortunately it is quite rare. ...Read more

Dr. Faisal Qureshi
154 Doctors shared insights

Biliary Atresia (Definition)

Biliary atresia abnormal biliary tract that block bile from moving from liver to intestine. Bile backs up in the liver causing scarring and damage to liver cells. Symptoms become apparent from 2 - 8 weeks of age Below is a website with more information about biliary ...Read more


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What exactly is biliary atresia?

What exactly is biliary atresia?

Birth defect: Malformation and scarrng obliteration of the bile ducts. Starts at birrth and progresses. Any infant who is jaundiced after one month of age needs a bilirubim level and a gallbladder ultrasound. Will need surgical correction prior to 60 days of life. ...Read more

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What is done for biliary atresia?

What is done for biliary atresia?

Depends on situation: If picked up early enough, some respond to surgery to re-establish bile flow. If operated later than 10 weeks of age, most will need a liver transplant to survive. All cases are quite unique & conferring with the treatment team will provide the best information. ...Read more

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Anyone's baby got biliary atresia?

Anyone's baby got biliary atresia?

Yes: Several in las vegas. About one third do well. One third will do well for a time and will eventually need a liver transplant. Another third do not benefit from a kasai procedure and go straight to liver transplant. ...Read more

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What exactly causes biliary atresia?

What exactly causes biliary atresia?

See below: The causes of biliary atresia are not well established and are probably multifactorial; genetic factors may play a permissive role in some cases, but infectious, toxic, or immunologic mechanisms are probably involved. ...Read more

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What is the disorder biliary atresia?

What is the disorder biliary atresia?

Bile Duct Blockage: The bile duct carries the bile formed in the liver to the small intestine. Any disease that narrows, scars, or obstructs the duct can be called atresia. In some cases a patient is born with a narrow duct, called congenital atresia. In other cases chronic inflammation, infection, or even rejection of a liver transplant can cause scarring or narrowing of the duct. ...Read more

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What are the tests for biliary atresia?

Multiple: Usually start with laboratory tests followed by ultrasound, scintigraphy and biopsy. The gold standard is an operative cholangiogram. ...Read more

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How is biliary atresia generally treated?

Surgery: Once the diagnosis is made and if the baby is considered an appropriate candidate, the approach is surgical. As the problem is lack of drainage of bile from the liver to the intestine, a new connection is made between the liver and intestine. It is called a portoenterostomy or a kasai procedure. Sometimes the child is not a candidate and may need transplantation of liver. ...Read more

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Describe the features of biliary atresia.?

See below: Jaundice (yellow eyes and skin) is the first sign of ba. The onset occurs any time from birth up to 8 weeks of age, and it is unlikely to appear later. Some infants have pale, gray (acholic) stools. Most infants have dark urine because of bilirubin excretion into the urine. If the jaundice has gone unnoticed and the disease progresses an enlarged liver and spleen may develop. ...Read more

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How is biliary atresia typically diagnosed?

Multidisciplinary: This diagnosis is made by a team of neonatologists, pediatric surgeons and pediatric gastroenterologists. It includes blood test, an ultrasound, a nuclear scan called hida scan to evaluate drainage of the liver, a liver biopsy and finally a cholangiogram. As you can see it is not straightforward and that is why so many specialists are required. ...Read more

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What are common symptoms of biliary atresia?

Jaundice: Yellow discoloration of the whites of eyes, skin, darkening of urine and pale acholic stools. Elevation of direct bilirubin. Absence of gall bladder on ultrasound. ...Read more

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What is biliary atresia and how is it treated?

Obstruction of bile: Biliary atresia is a disease of infants and newborns that results in obliteration of the bile dusts resulting in jaundice and eventually liver failure. It needs to be addressed early before infant is two months old. Surgery can correct it in one third of the cases. Any baby who is jaundiced after three weeks of age needs to be worked up. ...Read more

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Biliary atresia, is it a hereditary condition?

Not hereditary: Scientists do know that biliary atresia is not hereditary; parents do not pass it on to their child. It is also not contagious, and it is not preventable. ...Read more

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Who is more likely at risk for biliary atresia?

Post Transplant: There are two forms of biliary atresia - congenital (at birth) or acquired. The acquired type most often occurs in the setting of autoimmune disease (though no way to calculate risk) and is one form of chronic rejection of a transplanted liver allograft. ...Read more

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What happens if the biliary atresia is left untreated?

What happens if the biliary atresia is left untreated?

Liver failure: True biliary atresia with chronic biliary retention causes cirrhosis (scarring) of the liver, leads to liver failure, unless treated. ...Read more

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What are common symptoms and signs of biliary atresia?

What are common symptoms and signs of biliary atresia?

Jaundice: Persistent jaundice in the newborn which is of the direct type or conjugated type is the early sign of biliary atresia. If it goes undetected in the newborn period, the child can develop liver failure. ...Read more

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Are there different options for treating biliary atresia?

Depends: Ba describes a variable issue that is basicly plumbing too small to let the waste drain out of the liver. Intrahepatic (small drainpipes inside the liver) it is worse than extrahepatic (pipes outside liver). If a bypass can be created by 6-8wks, drainage can improve. However, many of these must have living donor partial liver transplant when or if the liver fails. ...Read more

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What is the definition or description of: Biliary atresia?

What is the definition or description of: Biliary atresia?

Biliary Atresia: Biliary atresia abnormal biliary tract that block bile from
moving from liver to intestine. Bile backs up in the liver causing scarring and damage to liver cells. Symptoms become apparent from 2 - 8 weeks of age
Below is a website with more information about biliary atresia
https://www. Cincinnatichildrens. Org/health/b/biliary ...Read more

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How often does biliary atresia occur and who is more likely at risk?

1/ 10-20, 000 births: The cause of biliary atresia is unknown, although several mechanisms have been implicated including viral infections, genetic causes and toxin exposure. ...Read more

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Biliary atresia treatment?

Kasai procedure: Biliary atresia is most often diagnosed in the neonates. The first line treatment is a surgical procedure called portoenterotomy (kasai) in which a loop of intestine is connected to the liver to act as a conduit for bile drainage in place of the missing bile ducts. The beneficial effects of this procedure, however, is often short-lived many children went on to require liver transplantation. ...Read more

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What is the liver biliary atresia?

Biliary atresia: Biliary atresia is a congenital scarring of the biliary ducts. These ducts transport bile made in the liver to the intestine so one can digest fats. The ducts scar and obliterate. Bile then cannot exit the liver which poisons the liver. These infants need corrective surgery before they are 2 months old. ...Read more

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Is there a syndrome with biliary atresia and fibrosarcoma?

No relationship: Biliary atresia is a condition in the young where the bile duct system of the liver closes down destroying liver function and leading to cirrhosis. Fibrosarcoma is a soft tissue lesion primary found as a mass arising in muscle tissue which best responds to surgical resection, but left alone will metastasize to organs like the lung. ...Read more

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Is it normal for people to have biliary atresia past infancy and into adulthood?

No: Biliary atresia is a disease of infancy. However there are diseases such as biliary cirrhosis which do occurr in adults. ...Read more

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What nutritional concerns should I be aware of if I am suffering from biliary atresia?

Fats, A, D, E, K, Zinc: Biliary atresia patients may have problems absorbing fats, can lead to deficiencies of fat soluble vitamins a, d, e, k, and calories. Can also have problems with zinc nutrition, should see doc and rd re: feeding and supplement plan. ...Read more

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Please let me know if there is a syndrome that has to do with biliary atresia and fibrosarcoma?

Syndrome: As far as I know there is no known syndrome between biliary atresia ans fibrosarcoma ...Read more

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What happens if the initial treatment for biliary atresia fails?

What happens if the initial treatment for biliary atresia fails?

Transplant: Treatment for biliary atresia is a kasai procedure which should be done before 60 days of life to be effective. One third of patients will do well and be cured. One third will do well for a period of time (years) but will eventually need a liver transplant. The final third will fail kasai and need a liver transplant sooner. ...Read more

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Is biliary atresia detected before birth?

Is biliary atresia detected before birth?

No: Biliary atresia is unsuspected until there is a persistent rise in bilirubin of the direct type. Initial imaging study should be a preprandial gall bladder ultrasound to see if gall bladder is present. ...Read more

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Is diarrhea bad when you have biliary atresia?

See below: If it is grey or white, yes. See your doctor asap. ...Read more

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Is surgery a possible cure for biliary atresia?

Is surgery a possible cure for biliary atresia?

YES: Biliary atresia involves both intra- and extra hepatic bile duct pathology. Standard extrahepatic bypass can provide extended survival for a minority of patients. Liver transplantation provides the only possibility for cure, though it carries with it significant morbidity and mortality. ...Read more

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What are available treatment options for biliary atresia?

Surgery: Kasai procedure attaches liver to bowel to drian bile. Nutrition support, especially for calories, fats, fat soluble vitamins, zn. May need liver transplant. ...Read more

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What can be done to relieve itching for patients with biliary atresia?

Resins, antihistamin: Bile salt resins to bind these in the gut, antihistamines. ...Read more

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Please explain why newborn who has biliary atresia can develop spider angioma?

Liver disease: This is a secondary effect from the liver disease that results from biliary atresia. The exact cause is not clear. ...Read more

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I have depression, as a result I'm a smoker. Would this worsen my biliary atresia?

I have depression, as a result I'm a smoker. Would this worsen my biliary atresia?

Whoa: With all due respect, depression does not require smoking. It's a very addictive habit for sure -- and once started, is a challenge to stop. But your comment reads as if depression leaves smoking as your only choice. Smoking worsens biliary complications after liver transplant for biliary atresia. . . Best to keep liver safe from toxins too. Your liver and lungs would be grateful; your doc too. ...Read more

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I have biliary atresia, symptoms are showing slow failure. I have low energy levels. Would taking vitamin tablets help me?

I have biliary atresia, symptoms are showing slow failure. I have low energy levels. Would taking vitamin tablets help me?

Possibly: Patients with biliary atresia should take replacements for fat-soluble vitamins which are a, d, e, and k. ...Read more

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Is it likely for me to recieve disability for a chronic liver disease, biliary atresia?

Hard to say: A lot depends on your present health status. Many will do well after a kasai. Some will need liver transplant. Services vary from state to state. Check with you local health department. ...Read more

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When is a liver transplant necessary if I am suffering from biliary atresia?

Eventually: When a patient has biliary atresia then progression of liver failure may be slowed permanently or partially. Liver function must be continually monitored. Any rise in liver function tests or signs of coagulopathy or portal hypertension need to be assessed by liver transplant specialists. ...Read more

Dr. Lawrence Kessler
1 Doctor shared a insight

Biliary (Definition)

Biliary means anything related to the production, storage, secretion, or flow of bile, whether in the liver, bile ducts, gallbladder, ...Read more


Upper Abdomen (Definition)

Draw a transverse line through the umbilicus and the upper abdomen includes every part of the belly above this line and below the ...Read more