Doctor insights on:
Medicine For Azt Allergy
Allergies occur when your immune system is triggered by envirionmental factors it should ignore--for example, pollen in the air, or dander on a cat or dog--and creates cells to fight against them. An allergic reaction typically causes itching, congestion, or drainage, and ...Read more
Just curious student: have new HIV drugs changed much since the days of azt (zidovudine)? Do new drugs like stribild have a chance of being resisted?
Antiretrovirals: The HIV mutates continuously, and this is one of several reasons why combination therapy with several drugs attacking the virus in different stages of its life cycle are necessary. Development of resistance is very common and when this happens, alteration of the therapeutic choices are often made. ...Read more
Can retrovir (zidovudine) and stavudine (d4t, zerit) be taken together in an HIV regimen of medicine?
Can you tell me for prevent HIV , taking zidovudine & lamivudine ( or combivir ) and isentress (raltegravir) it isenough as pep medicine?
New drugs better: Azt (zidovudine) is an old drug with considerable toxicity. It's not widely used in the U.S. Anymore. The many antiretroviral agents that have taken its place can still have side effects, but they are far safer and better tolerated than the older drugs...And far safer and less toxic than HIV infection. ...Read more
That depends: Azt (zidovudine) ishas a lot of side effects and toxicity, which is why it's less often used in the U.S. And other resource-rich countries these days. The more commonly used drugs in this class (the nucleoside analog reverse transcriptase inhibitors, or nrtis) are tenofovir, abacavir, lamivudine, and emtricitabine. These drugs are safer, more convenient, and more potent. ...Read more
Depends: The amount of time for resistance to happen to azt (or zidovudine) depends on how adherent one is in taking their HIV medications. Standard HIV regimen usually includes at least a combination of 3 medications, often called haart (highly active anti-retroviral therapy). If someone is close to 100% adherent to their haart, resistance is very unlikely. However, lesser adherence leads to resistance. ...Read moreSee 3 more doctor answers
Depends: The amount of time for resistance to happen to azt (or zidovudine) depends on how adherent one is in taking their HIV medications. Standard HIV regimen usually includes at least a combination of 3 medications, often called haart (highly active anti-retroviral therapy). If someone is close to 100% adherent to their haart, resistance is very unlikely. However, lesser adherence leads to resistance. ...Read moreSee 2 more doctor answers
HIV clinic: You don't want an "azt clinic, " you want an "hiv clinic." you can ask your doctor, or a local aids service organization. There are also websites where you can find out about local HIV centers and clinicians in your area, including http://www.Hivma.Org and http://www.Aahivm.Org. ...Read more
Yes: That would generally be done only if you had some degree of nucleoside analog resistance, such as resistance to the Emtricitabine component of atripla. ...Read more
Although it: Has chemical structure of a nucleoside, and 6-mercaptopurine analog, an agent used to treat leukemia, azt (zidovudine) was inert against human leukemia and solid tumors. It has reverse-transriptase inhibition, rns virus need that enzyme to make dna, which in turn can insert into human dna. It is this use that led to testing against HIV virus. ...Read moreSee 1 more doctor answer
Yes, but...: You can, though it's an unusual combination. Azt (zidovudine) is no longer widely used in the U.S. Because of toxicity. Atripla alone is effective treatment against HIV infection in someone without drug resistance. The combination of azt (zidovudine) and Atripla could be used in someone with a modest degree of resistance to the nucleoside analog class of antiretrovirals, but it wouldn't be my first choice. ...Read more
We use other drugs: There is no "azt (zidovudine) program." azt (zidovudine) is a drug that is no longer widely used, as it has been replaced by a number of easier, safer, and more effective drugs that, when used in combination, stop the HIV virus from replicating and infecting new cells. These leads to improvement in immune function and a much lower risk of illness and death. ...Read more
Just AZT (zidovudine)?: If he's only taking azt (zidovudine), (zidovudine) stopping it may not cause many problems, because azt (zidovudine) alone is an ineffective way to treat hiv. If he's taking azt (zidovudine) in addition to other HIV drugs, then stopping will cause his viral load to go up, his CD4 count to decline, and he will be at greater risk for dying, progressing to aids, or developing other complications. He could also develop drug resistance by stopping. ...Read more