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Doctor insights on: Medicine For Antiphospholipid Syndrome

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What is antiphospholipid syndrome?

What is antiphospholipid syndrome?

Blood clots: Antiphospholipid Syndrome (APS) can exist on its own or in association with another autoimmune condition such as lupus. It is caused by antibodies that increase the risk of blood clots. These antibodies also interfere with routine laboratory tests of blood clotting by binding to phospholipids, hence the name. The symptoms of APS can include blood clots, Raynaud's and pregnancy loss. ...Read more

Dr. Victor Beshay
331 doctors shared insights

Antiphospholipid Syndrome (Definition)

Components in one's blood that can increase the risk of blood clots especially in the smallest ...Read more


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What leads to antiphospholipid syndrome?

It can be genetic: One can inherit this syndrome, or it may arise without any apparent history or cause. It is associated with multiple medical problems, including recurrent pregnancy loss. ...Read more

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Can you explain antiphospholipid syndrome?

Can you explain antiphospholipid syndrome?

Short description: It involves arterial or venous clotting or specific pregnancy complications, with laboratory evidence of anti-phospholipid antibodies. Autoantibodies, meaning produced and directed against one's self, are to plasma proteins (many:) altering normal clotting leading to thrombus (clot) and/or pregancy complications like fetal death, recurrent early pregnancy loss, eclampsia, and others. ...Read more

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What can trigger antiphospholipid syndrome ?

What can trigger antiphospholipid syndrome ?

Lupus, stress.: Systemic lupus erythematosus, chronic/acute severe stress and genetic predisposition all conspire to lead to antiphospholipid antibody syndrome. This is a very rare but devastating disorder that can have horrible perinatal outcomes with each pregnancy. Considered an autoimmune disorder, apls may have its etiological underpinnings in maternal-fetal cell trafficking, as most autoimmune conditions. ...Read more

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Can antiphospholipid syndrome (aps) be cured?

APL syndrome : Can be controlled and any complications from apl be treated . Spontaneous remission s possible over time . Needs careful vigilance and follow up by rheumatologist. ...Read more

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Can aps (antiphospholipid syndrome) cause ed?

Yes: The following published research article reported that 50% of the patients with aps had erectile dysfunction. http://lup.sagepub.com/content/21/3/319.abstract. ...Read more

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What sort of problem is antiphospholipid syndrome?

What sort of problem is antiphospholipid syndrome?

Autoimmune: Autoimmune means your body produces antibodies - cells that attack your own body. In antiphosopholipid syndrome the antibody which is made provokes blood clots (thrombosis) in both arteries and veins as well as pregnancy-related complications such as miscarriage, stillbirth, preterm delivery, or severe preeclampsia. ...Read more

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What can I expect from "antiphospholipid syndrome"?

Complex problems: The manifestations of aps range from having no symptoms at all to catastrophic, disastrous clotting affecting multiple organs leading to death within days. Many will present with blood clots, some with skin changes, others with low platelets or women will have repeated spontaneous miscarriages. Another autoimmune disorder may also be diagnosed such as lupus erythematosus. See:http://www.Apsfa.Org/. ...Read more

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Please explain antiphospholipid syndrome in common terms.?

Short description: It involves arterial or venous clotting or specific pregnancy complications, with laboratory evidence of anti-phospholipid antibodies. Autoantibodies, meaning produced and directed against one's self, are to plasma proteins (many:) altering normal clotting leading to thrombus (clot) and/or pregancy complications like fetal death, recurrent early pregnancy loss, eclampsia, and others. ...Read more

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What is the definition or description of: antiphospholipid syndrome?

Antiphospholipid antibodies: Antiphospholipid antibodies are components in one's blood that can increase the risk of blood clots especially in the smallest blood vessels called capillaries. These individuals are prone to deep venous thrombosis in the leg and potentially pulmonary embolus in the lungs. ...Read more

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What are the main symptoms of antiphospholipid syndrome that people have?

There are a few...: The criteria for the diagnosis of aps is based upon both clinical findings(what happens to you) and laboratory findings(results of blood tests). Some of the clinical findngs are a history of blood clots; fetal death over 10 weeks; delivery under 34 weeks due to preeclampsia; 3 or more recurrent miscarriages. Since aps can adversely affect a pregnancy, you need to discuss with your physician. ...Read more

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What should I expect from a condition known as "antiphospholipid syndrome"?

Hard to know: True anti phospholipid syndrome is rare we only diagnose this problem when people have a history of clotting problems the diagnosis has now been extended to people with 2 or more miscarriages. The diagnosis needs to be carefully considered if diagnosed Aspirin or Heparin maybe useful. ...Read more

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Antiphospholipid syndrome patients only between the ages of 18 - 30?

Common young/mid-age: Aps is commonly seen in the young and middle age group but can be seen in the pediatric and elderly population also. Since aps may be a part of sle (lupus), a sizable number of aps patients are young in common with the sle population. There is a female preponderance also. ...Read more

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Is there treatment for antiphospholipid syndrome?

Is there treatment for antiphospholipid syndrome?

Anticoagulation.: If you get bad blood clots from antiphospholipid syndrome, treatment with Coumadin (warfarin) or another anticoagulant might be recommended. ...Read more

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What is the treatment of antiphospholipid syndrome?

Depends: Aspirin or anticoagulants may be required. If severe, steroids, suppressive medications or intravenous gamma globulin may be required. ...Read more

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What are the effects of antiphospholipid syndrome on pregnancy?

Increased risk: Anti-phospholipid antibody syndrome can cause growth restriction, early onset high blood pressure of pregnancy (pre-eclampsia) and blood clots. Your doctor will likely prescribe blood thinners during your pregnancy and follow the babies growth with serial ultrasounds. ...Read more

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My mother has developed antiphospholipid syndrome. What is it exactly?

Autoimmune problem: With apa-s, the immune system produces antibodies against normal proteins in the body. Most importantly, blood clots can form in the legs and lungs, and there is a higher risk of strokes. As a gynecologist, I have concerns regarding a higher risk of miscarriages and stillbirths. Treatment centers on preventing a clot or treating one if it already exists. ...Read more

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Is there an aftermath of antiphospholipid syndrome?

Pregnancy outcome: Individuals with antiphospholipid syndrome may be at an increased risk of first trimester recurrent pregnancy loss. Treatments are available though to improve outcome. Make sure your OB or your fertility specialist knows so he/she can address appropriately. ...Read more

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When is the antiphospholipid syndrome treated with chemotherapy?

When is the antiphospholipid syndrome treated with chemotherapy?

Failure of other Tx: Apls (antiphospholipid antibody syndrome) if necessary can be treated first with steroids like prednisone. Sometimes just being on a blood thinner is enough to avoid blood clots that it can cause or miscarriages. Other treatments like Rituxan (rituximab) (antibody) have been used especially if low platelet counts are seen. If these initial tx fail, doctors may resort to chemo drugs like cyclophosphamide. ...Read more

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What is the recommended INR level for someone diagnosed with Antiphospholipid Syndrome?

See details: The range should be 2-2.5 but in severe cases a level of 2.5-3 may be warranted. ...Read more

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Also, is there any other interesting information you have on antiphospholipid syndrome prengnacy disorder?

Pregnancy Morbidity: Antiphospholipid syndrome can cause significant problems with pregnancy:one or more late-term (>10 wks' gest) spontaneous abortions;one or more premature births of a physically healthy newborn at or before 34 weeks’ gestation because of severe hypertension (eclampsia);
three or more unexplained, successive, spontaneous abortions before 10 weeks’ gestation. ...Read more

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If I have antiphospholipid syndrome, can I donate blood?

No, maybe for self : Aps is an autoimmune disease and antibodies are present in blood. Experiments of injecting serum (blood product) from aps patients to mice caused different changes in hyperactivity compared to normal serum or placebo. Aps may not be infectious but transient systemic effects can occur because of the presence of different anti phospholipid antibodies in the blood donation. Autologous donation is ok! ...Read more

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Would someone with antiphospholipid syndrome have an increase of factor 8?

Would someone with antiphospholipid syndrome have an increase of factor 8?

Usually NOT: The mechanism of increased clotting in antiphospholipid syndrome (aps) is complex involving many levels of the clotting cascade. Although a paradoxical prolongation of the prothrombin or thromboplastin time is seen in the lab test (blood looks thinner), what happens inside the body could be the opposite - an increased risk of clotting that has nothing to do with levels of factor 8. ...Read more

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Question about antiphospholipid syndrome? Is it diagnosed by lab tests or symptoms?

Question about antiphospholipid syndrome? Is it diagnosed by lab tests or symptoms?

Both.: Symptoms would lead a doctor to verify the diagnosis with a lab test. The symptoms would be bad blood clots, like a DVT or pe. ...Read more

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Can i still donate my organs if i have antiphospholipid syndrome? (i'm on xarelto for life)

Can i still donate my organs if i have antiphospholipid syndrome? (i'm on xarelto for life)

Yes. For transplant?: You've a rare condition (antiphospholipid antibody syndrome or APLAS), so regardless of whether your organs are viable for transplant, I am sure that they will be of use to the medical community that studies this disease. Whether organs can be placed in another depends on the condition that they are in at the time of "harvest". It's good let your wishes be known & thanks for being an organ donor. ...Read more

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Is it possible for a woman with endometriosis and antiphospholipid syndrome to get pregnent?

Absolutely: Endometriosis can affect fertility and apls can affect miscarriage. So the two affect different parts of the process. If you know you have both of them, then you should definitely seek fertility care at least for an evaluation to see how the endomeriosis is affecting things. And you would likely want to take Lovenox (enoxaparin) at a certain point just before or during pregnancy. ...Read more

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Are natural remedies for antiphospholipid syndrome safe?

Safe but don't work: Safe but not effective can be dangerous. Antiphospholipid syndrome is rare but can cause serious problems including blood clots in the legs or lungs which may be fatal, or pregnancy complications, such as multiple early miscarriages, late miscarriage, or severe pre-eclampsia. See a hematologist if you're not trying to conceive, reproductive endocrinologist (rei) if trying, high risk OB if pregnant. ...Read more