Doctor insights on:
Medicine For Adrenal Suppression
If high cortisol can decrease serotonin levels then can low cortisol(like due to iatrogenic adrenal suppression) increase serotonin levels?
Is the risk of adrenal suppression/insuffiency increased or the same at, let's say, 35 mg prednisone compared to 45 mg? Or any dosage above 7.5 equal?
0.5 mg florinef (fludrocortisone) every other day works so well for my POTS but I'm so afraid I will end up with adrenal suppression & osteoporosis when I'm older. Help?
POTS is a 'syndrome': "Syndrome" = "we don't get it". In POTS, there is an unexplained alteration in the balance of stress/relaxation response (autonomic system) that coordinates heart rate and blood vessel size and so-on. After cardiology has assured no dangerous abnormalities, it makes sense to try cranial osteopathy or craniosacral which can balance autonomic system. Look for credentialed providers. ...Read more
Is it risky to be on 0.05 mg Florinef (fludrocortisone) ever other day for POTS? I struggle with when off it. Concern for bones, thinning skin, adrenal suppression
Non-issues: B"sd Florinef (fludrocortisone) is the only aldosterone like agent available. To my knowledge, unlike corticosteroids it does not suppress the pituitary adrenal axis or cause thinning of the skin. If anything it should decrease renal calcium excretion and possibly decrease bone loss. the main concerns; 1.hypokalemia 2. hypertension, especially when supine. glad to discuss further ...Read more
Florinef (fludrocortisone) for POTS. Wish 2wean off eventually but sx come back. Are most w/POTS on longterm?Isn't it bad to be on longterm(bones,adrenal suppression)
Currently there is: no cure for POTS. All treatments are palliative to avoid symptoms and complications from syncope. It is a molecular genetic abnormality of the autonomic nervous system. Although there is potential for long term side effects from the Florinef (fludrocortisone) the alternative is harm and disability from non treatment. Of course Sx come back without Florinef (fludrocortisone). Ask about other therapies that might be reasonable. ...Read more
Acth lab <5 1 wk p completing 15day prednisone taper. Is adrenal suppression artificial? Concerned?20mg x3tabsx 5days, x 2x 5 days, x1 x 5 days.
No: It would cause severe allergic reactions and potentially even death. Plus, i don't know anyone who wants to donate their adrenals. Don't get your medical information from friends, tv or internet scams. ...Read more
I know that adrenal fatigue is not a recognized diagnosis in science based medicine. Are there any other venues that can help me?
Adrenal fatigue: "adrenal fatigue" is often "diagnosed" in people who are not feeling well. To say it is not adrenal fatigue is not to deny your symptoms of lethargy. You feel bad, and want to feel better. Perhaps start with a primary care provider who will work with you. A good pcp will help you figure out what's wrong, and try to prevent you from harmful or expensive nostrums that will do no good. ...Read more
Where to find about drugs that should not be given to patients suffering from adrenal insufficiency?
What tests should one ask for adrenal insuf diagnosis (iatrogenic induced)? Medicines, exercises, food, natural remedies to help? N Texas specialists?
Adrenals can be: tested in the conventional way starting w/family doc. He/she may refer you to an endocrinologist. A more alternative approach is to get an Adrenal Stress Index test from Diganostechs lab in WA state. It uses saliva as the sample and most conventional docs won't be trained in this. Then supplements can be used based on test results through a nutritionally oriented physician. Peace & health. ...Read more
Congenital adrenal hyperplasia -non classical kind, what are some remedies to help with side effects of disease and medicine like steroids?
Adrenal hyperplasia: The commonest type of congenital adrenal hyperplasia is caused by deficiency of 21 hydroxylase, classical type presents at birth, but non classical may present later in early childhood or during puberty.It is difficult to answer all about it, but some salt depleted patients need to be on steroids and the patints need to be monotored for other defects, it should be trated by a pediatric endocrinologist. ...Read more
I have issues with adrenal, pituaitary thyroid etc.. But i learn that conventional , medicine does not recognize adrenal disfunction. It is or it is working - does not matter how poorly or it is not, like addison's and you dead.
I also understand that
Evaluated by endo:
hypoadrenalism either due to a problem with pituitary gland or the adrenal gland, can be easily diagnosed with appropriate hormone testing by a trained endocrinologist. It is highly important, to establish the diagnosis before starting the treatment, as wrong diagnosis has consequences.
I would recommend referral to an endocrinologist for evaluation. ...Read more
Can afinitor (everolimus) helps to prevent the spread of adrenal gland cancer? How it works? Any clinical trial on this drug against adrenal gland cancer in USA?
Not confirmed: That data on this drug for adrenal cancer is very limited. Efficacy has not been confirmed yet. It is not approved in the United States for this indication. I am not aware of clinical trial on this disease but you may want to contact major centers or check clinicaltrials.gov ...Read more
Does low dose cortef (hydrocortisone) heal the adrenals, helping the patient to feel well again and enabling them to eventually go off the drug? Non-addison's.
No: Taking any dose of steroid causes the adrenal glands to work less, as the pituitary gland regulates your adrenal hormone level. If your adrenal glands truly do not work, you need lifelong adrenal hormone replacement. However, i see people who have been diagnosed with "adrenal fatigue". This is not a true medical diagnosis. Most of these people have no adrenal problem at all. ...Read more
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