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Doctor insights on: Medicine For Acute Tubular Necrosis

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Can you explain acute tubular necrosis?

Can you explain acute tubular necrosis?

Ischemia, drugs: Acute tubular necrosis (atn) can happen if the kidney has severely reduced blood supply (ischemia).

This could be caused by hypotension (very low blood pressure), volume depletion (as a result of illness or trauma), problems with the blood vessels supplying the kidneys (renal artery blockage), and drugs that affect the flow of blood to the kidneys.

Drugs and toxins can also directly cause atn. ...Read more

Necrosis (Definition)

Necrosis is the the death of cells and tissue. In dentistry, root canals are often needed when the pulp tissue inside a ...Read more


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What are the causes of acute tubular necrosis?

What are the causes of acute tubular necrosis?

Ischemia, drugs: Acute tubular necrosis (atn) can happen if the kidney has severely reduced blood supply (ischemia).

This could be caused by hypotension (very low blood pressure), volume depletion (as a result of illness or trauma), problems with the blood vessels supplying the kidneys (renal artery blockage), and drugs that affect the flow of blood to the kidneys.

Drugs and toxins can also directly cause atn. ...Read more

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I have decreased urination, could this be caused by acute tubular necrosis?

I have decreased urination, could this be caused by acute tubular necrosis?

Very unlikely: Decreased urination almost always relates to either reduced fluid intake or increased fluid losses such as diarrhea or increased sweating. In the rare instance when low urine output is due to kidney disease, weight gain from the accumulated water retention should be measurable on a daily bases. ...Read more

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What is the difference between acute renal failure and acute tubular necrosis?

What is the difference between acute renal failure and acute tubular necrosis?

Here are some...: Acute renal failure is a general term denoting kidneys not able to good enough to manage water and electrolytes due to acute conditions such as shocks from various reasons, and acute tubular necrosis denotes what can be seen in kidney tissue under microscopic exam if biopsy is done, but not necessary for almost all cases. Clinically, they all tell us kidneys not working enough from acute causes. ...Read more

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How is a tubular necrosis diagnosed?

How is a tubular necrosis diagnosed?

ATN: Acute tubular necrosis is classified as a "renal" (i.e. Not pre-renal or post-renal) cause of acute kidney injury. Diagnosis is made by a fena (fractional excretion of sodium) > 3% and presence of muddy casts (a type of granular cast) in urinalysis and by histopathology. ...Read more

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Can a tubular necrosis be found by performing a kidney and bladder ultrasound?

Can a tubular necrosis be found by performing a kidney and bladder ultrasound?

Not usually: Acute tubular necrosis is classified as a "renal" (i.e. Not pre-renal or post-renal) cause of acute kidney injury. Diagnosis is made by a fena (fractional excretion of sodium) > 3% and presence of muddy casts (a type of granular cast) in urinalysis. This cannot be accurately diagnosed by imaging studies. ...Read more

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What's the treatment for acute tubular necrosis?

Complex: Identify the cause of atn, resolve it, and prevent further blood pressure, hypoxia, or nephrotoxin insults while the kidney heals. ...Read more

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2 year ago I developed acute pancreatitis with necrosis and fluid sacs following an ercp. I feel ill and my immune system is low, is this related?

2 year ago I developed acute pancreatitis with necrosis and fluid sacs following an ercp. I feel ill and my immune system is low, is this related?

Ercp pancreatitis: This is quite common. You may have a pseudocyst of the pancreas. You should get evaluated fully. Also any chronic low grade pancreatitis will affect your general well being. ...Read more

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How long does it take amoxicilin to get rid of acute necrotic ulcerative gingivitis?

How long does it take amoxicilin to get rid of acute necrotic ulcerative gingivitis?

Need other treatment: Amoxicillin alone won't get rid of acute necrotizing ulcerative gingivitis. You also need to have some professional cleanings to get rid to the bacterial toxins that are irritating your gingiva. You also need to increase your brushing and flossing habits, and possibly incorporate a waterpik in your daily regimen. ...Read more

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Extensive tumor necrosis! How to diagnose, what to do?

Remove if possible: When tumor get very large and essentially loose blood supply necrosis can set in. If extensive, tumor necrosis syndrome develops and release of toxins into the blood stream can occur. At this point debulking of the lesion is beneficial. ...Read more

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How do subarachnoid haemorrhages result in cell necrosis?

Cell death: Necrosis is cell death. Anything that disrupts the complex system that keeps cells alive can cause cell death. Subarachnoid hemorrhage is a bleed in the brain. The pressure from extra blood in a small space can crush cells, and disrupt fragile capillaries that bring oxygen to cells. This, cell death ...Read more

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Is fat necrosis or abscess dangerous?

Is fat necrosis or abscess dangerous?

They're different: Fat necrosis is typically painful but jot dangerous. Abscesses can be dangerous if not properly treated. ...Read more

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Which test can diagnose pancreatic necrosis?

Imaging: Hi. The blood tests, amylase & lipase (two pancreatic digestive enzymes) can diagnose pancreatitis, but the best rests for pancreatic necrosis are probably imaging. Best imaging for p. necrosis would be CT with contrast. Abdominal MRI with contrast is also excellent, although not done as routinely. Transabdominal ultrasound doesn't see the pancreas super well, by transesophageal ultrasound is good ...Read more

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Does skin necrosis require immediate surgery?

Does skin necrosis require immediate surgery?

Yes, it may: You should be evaluated immediately, hopefully, the skin can be saved! ...Read more

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I have necrosis of the liver what can I expect?

I have necrosis of the liver what can I expect?

What's the cause?: An elite athlete can kill off huge numbers of his liver cells in a prolonged endurance event and they grow right back with the liver restored perfectly. This also happens after prolonged shock with recovery. If you have a chronic hepatitis (viral, immune) with ongoing cell damage, the outcome is whatever is expected for the hepatitis. Insist your physician tell you what's killing liver cells. ...Read more

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What happens to the testicle as it enters necrosis?

Testis: Necrosis means death of the testicle. It eventually shrinks and essentially disappears. If you are concerned about fertility, necrosis of the testicle in the scrotum may lead to production of antibodies that may lead to infertility. ...Read more

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What can you tell me about the tumor necrosis factor?

Cytokine: Tumor necrosis factor was a cytokine first isolated from macrophages and CD4 cells in response to understanding how Coley's toxin worked. It was felt to be the factor that induced destruction of malignancies but when sequenced proved to be the same molecule as cachexin, a chemical produced by tumor like pancreatic cancer that induced cachexia in patients. ...Read more

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What is the role of mitochondria on apoptosis and necrosis?

Apoptosis: You ask and important tough question. I suggest you go online and read the several articles available. It will take some time but will be worth it. If you have difficulty with that please send another request with more specific questions. I think you won't need to but don't be shy. ...Read more

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What is the difference between kidney nephrosis & kidney necrosis?

What is the difference between kidney nephrosis & kidney necrosis?

Protein: necrosis refers to the death of cells, usually tubular kidney cells, also found though are vascular necrosis with vasculitis and glomerulonephrtis.

Nephrosis refers to the presence of lots of protein in the urine. ...Read more

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What happens to testicle after necrosis? What time needs to shrink?

What happens to testicle after necrosis? What time needs to shrink?

4th time: What are your symptoms? How did you diagnose yourself? There will be a lot of pain but you previously said no pain. Please see doctor if you still have not. Wish you the best. ...Read more

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Hip necrosis and still young please tell me where to turn for help?

Hip necrosis and still young please tell me where to turn for help?

Orthopaedic Surgeon: You need to see an orthopaedic surgeon who specializes in hip reconstruction. If surgery is recommended, there are many options available. ...Read more

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On PET scan the phrase "central photopenia suggesting necrosis" what does this mean?

On PET scan the phrase "central photopenia suggesting necrosis" what does this mean?

Usually necrosis: PET scan uses F18 FDG (a glucose metabolite) to localize active metabolic processes such as tumors. The uptake of the radiopharmaceutical is considered hot when increased over normal tissues or background Sometimes central portion of tumor is photogenic or cold reflecting necrosis or death of some of tumor. Necrosis can be related to chemotherapy or on presentation when tumor outgrows blood supply ...Read more

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Predinisone for 6 days. 100mg, 90, 70, 60, 60, 40 then done. Was this safe? Am I at risk for adrenal damage or necrosis now?

Totally safe!: Hi. Yes, a prednisone taper such as you describe is 100% safe. Can't say if it was effective, because you don't even tell us what your doc is/was treating. But a taper of those doses over that time is 110% safe. And "adrenal necrosis" is NEVER an issue with a glucocorticoid burst & taper! It's pituitary corticotroph suppression we worry about with prolonged high-dose glucocorticoid therapy. Cheers ...Read more

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Prominent interface hepatic score 4/4 Spotty necrosis score 2/4 Fibrous expation of portal area score 3/6 What would that mean?

Prominent interface hepatic score 4/4 Spotty necrosis score 2/4 Fibrous expation of portal area score 3/6 What would that mean?

GI: Its best you consult a Gastroenterologist to explain this to you. I'm sure a healthtap doctor specializig in GI can be of some assistance. ...Read more

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What is necrosis? Just irrevesible cell then dead off and cause inflammation? Does it mean whenever there is a mild injury, our cell die and necrosis?

What is necrosis? Just irrevesible cell then dead off and cause inflammation? Does it mean whenever there is a mild injury, our cell die and necrosis?

Necrosis: Cell death is said to occur by two alternative, opposite modes: apoptosis, a programmed, managed form of cell death, and necrosis, an unordered and accidental form of cellular dying. ...Read more

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How do you treat avascular necrosis?

How do you treat avascular necrosis?

Surgery, meds: The most common solution is joint replacement surgery, but bisphosphonate medications can be used first to try to slow the progression of bone death. ...Read more