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Doctor insights on: Medical Treatment For High Ige

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How does anti-ige treatment work?

How does anti-ige treatment work?

Decoupling: Allergic illness occur when allergens activate mast cells releasing biochemicals. Allergens interact with mast cells through ige antibodies attached to mast cell receptors. Each ige antibody is specific for an allergen. Ige lasts for months but ultimately degrades & must be replaced. Anti-ige blocks the replacement process. Mast cells become denuded of ige & can no longer respond to allergens. ...Read more

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Is there any definite treatment for Hyper IgE Syndrome? I mean one that is not only maintenance of symptoms but may lead to actual improvement?

Is there any definite treatment for Hyper IgE Syndrome? I mean one that is not only maintenance of symptoms but may lead to  actual improvement?

No not at this time: Hyper IgE syndrome is an inherited immunodeficiency disorder. The current treatments are supportive, prophylatic and treatment of infections as they occur. You can read more information on http://primaryimmune.org/about-primary-immunodeficiencies/specific-disease-types/hyper-ige-syndrome/ ...Read more

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My IgE level is 4000 iu/ml, normal is <150 , I have nasal allergy and severe asthma, what is the treatment ?

My IgE level is 4000 iu/ml, normal is <150 , I have nasal allergy and severe asthma, what is the treatment ?

The asthma: It is not unheard of that many people can have a very high ige level with asthma or hay fever. As mentioned previously by another doctor , severe asthma along with high ige may signify the existence of allergic bronchopulmonary aspergillosis (or mycosis). I urge you to consult a board-certified allergist asap. ...Read more

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I've seborrheic dermatitis white flake itchy scalp symtoms get worse when i eat diary nuts fish soy my IgE level is 498 is any treatment available ?

I've seborrheic dermatitis white flake itchy scalp symtoms get worse when i eat diary nuts fish soy my IgE level is 498 is any treatment available ?

Atopic Dermatitis: You may have atopic dermatitis (ad) rather than seborrhea. About 40% of persons with ad have food allergy triggers. Allergy testing might reveal allergic triggers that you are unaware of, and avoidance these could make a big difference. Consult an allergist. ...Read more

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Is food allergy can be treated through immunotherapy or anti IgE therapy ?

Is food allergy can be treated through immunotherapy or anti IgE therapy  ?

No: It is not recommended to use immunotherapy for treatment of food allergy. There are studies being done to try to desensitize by giving small amounts of the food frequently but these are still in a research phase. Anti-ige treatment with omulazimab is approve for asthma treatment in the us and it will often make the patient less reactive to foods they are allergic to. ...Read more

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What can cause high total IgE besides an allergy!? Doctors can't help me with my symptoms

What can cause high total IgE besides an allergy!? Doctors can't help me with my symptoms

Several: Depends on how elevated it is, some high values do not mean anything. However one can have a blood disorder producing a high level of ige, parasite infections may also cause ige to be elevated. You should check with an allergist to check for a mast cell disorder as well. ...Read more

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I don't have allergy symptoms but have had high IgE (>770) for yrs. My concerns were dismissed by specialist. I saw and want to addr it. Pls advice.?

I don't have allergy symptoms but have had high IgE (>770) for yrs. My concerns were dismissed by specialist. I saw and want to addr it. Pls advice.?

Not to worry: A high ige does not necessarily mean that you have allergies. False positive test results are very possible with ige levels to the point that i hardly ever order them. What counts is your symptoms and overall clinical picture. ...Read more

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I have extremely high ige, any chance it's not allergies?

I have extremely high ige, any chance it's not allergies?

Yes: Very high ige can be associated with atopic dermatitis (allergic eczema) and also with uncommon immune deficiency called hyper ige syndrome--typically starts in children. Usually, it is associated with allergies. ...Read more

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Doc How can I stop the high level Ige with which medicine?

Doc How can I stop the high level Ige with which medicine?

Treatment: for isolated IgE elevation is debatable. But if you have symptoms from allergies, then anti-histamines help. ...Read more