Doctor insights on:
Measurement Of Ionized Calcium In Dialysis Patients
Why r my calcium levels normal, while my ionized calcium levels are high? I have bone pain, fatigue, kidney stones. I don't know pth level, or vit. D.
Most calcium in the blood is bound to a molecule called albumin, and this calcium fluctuates depending on the level of albumin. The rest is "ionized" calcium and this is freely available for biologic processes. Labs used to only be able to measure total calcium - calcium bound to Albumin + ionized. Now we can measure ionized calcium and not be mislead that calcium is low ...Read more
Ionized Calcium 4.65, PTH 133, Calcium 10.3, Vitamin D 7, Phosphorus 4.9, recurrent Kidney stones. Thyroid lobe, two parathyroids removed in 2004.
Uncertain: These test results don't add up to a straight forward answer. However, I would be concerned about the possibility of recurrent primary hyperparathyroidism. You should take Vit D to eliminate Vit D deficiency as a cause for high PTH levels. Once this is done, if you still have high PTH with high calcium levels, you have recurrent primary HPTH and will need surgery again. ...Read more
Yes: Calcium has a positive electrical charge; many proteins have a negative electrical charge. So, the opposite charges can cause calcium can bind to proteins. The test for serum calcium measures all of the calcium in the blood (bound & unbound). The ionized calcium measures just the unbound. ...Read moreSee 1 more doctor answer
Just watch it: This is at the upper limit of normal for most reference ranges, and these in turn are set up so that several percent of healthy people will fall on either side. Watch and see what it's like on your next routine set of labs unless you develop symptoms. ...Read moreSee 1 more doctor answer
Don't think so.: Each lab report should have a reference range of "normal" values. The reference range changes from lab to lab because each lab runs their test differently. Automated (machine) analyzers tend to have less variability, and in most of those machines, an ionized calcium of 1.1 to1.2 Is about in the middle of the "reference range". ...Read more
Ionized calcium: Measurement is more accurate than total calcium because it measures the amount of calcium in the blood that is actually available for cellular metabolism. Many possibilities for causes and consequences of low or high calcium, too many to list here. Ask your doctor to interpret your results for you. ...Read more
Unbound calcium: Most calcium in the blood is bound to a molecule called albumin, and this calcium fluctuates depending on the level of albumin. The rest is "ionized" calcium and this is freely available for biologic processes. Labs used to only be able to measure total calcium - calcium bound to Albumin + ionized. Now we can measure ionized calcium and not be mislead that calcium is low because Albumin is low. ...Read more
Depends on context: More information is needed, especially in regards to a correction factor against the serum albumin in hypocalcemia. Ionized calcium is a good measure too, but again, context is necessary. Please see your doctor to help you with clinical context of laboratory values, because the values are not really significant until they are applied to your clinical situation. ...Read moreSee 2 more doctor answers
Simple answer is that it is a medical technology used primarily to provide an artificial replacement for lost kidney function in people with renal failure. Hemodialysis remove wastes and excess water from the blood by circulating blood outside the body through an external filter, called a dialyzer. Blood and dialysate flow through in opposite directions and the ...Read more
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