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Doctor insights on: Measurement Of Ionized Calcium In Dialysis Patients

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Why r my calcium levels normal, while my ionized calcium levels are high? I have bone pain, fatigue, kidney stones. I don't know pth level, or vit. D.

Why r my calcium levels normal, while my ionized calcium levels are high? I have bone pain, fatigue, kidney stones.  I don't know pth level, or vit. D.

Half if calcium: In the blood is bound to proteins and inactive. The other, active, half is the ionized or free calcium, which is what really does the heavy lifting and is more accurate cllinically. You really need the other lab and a good endocrinologist. ...Read more

Dr. James Krick
36 doctors shared insights

Ionized Calcium (Definition)

Most calcium in the blood is bound to a molecule called albumin, and this calcium fluctuates depending on the level of albumin. The rest is "ionized" calcium and this is freely available for biologic processes. Labs used to only be able to measure total calcium - calcium bound to Albumin + ionized. Now we can measure ionized calcium and not be mislead that calcium is low ...Read more


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Ionized Calcium 4.65, PTH 133, Calcium 10.3, Vitamin D 7, Phosphorus 4.9, recurrent Kidney stones. Thyroid lobe, two parathyroids removed in 2004.

Ionized Calcium 4.65, PTH 133, Calcium 10.3, Vitamin D 7, Phosphorus 4.9, recurrent Kidney stones. Thyroid lobe,  two parathyroids removed in 2004.

Uncertain: These test results don't add up to a straight forward answer. However, I would be concerned about the possibility of recurrent primary hyperparathyroidism. You should take Vit D to eliminate Vit D deficiency as a cause for high PTH levels. Once this is done, if you still have high PTH with high calcium levels, you have recurrent primary HPTH and will need surgery again. ...Read more

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What is the definition or description of: ionized calcium?

What is the definition or description of: ionized calcium?

Unbound calcium: Most calcium in the blood is bound to a molecule called albumin, and this calcium fluctuates depending on the level of albumin. The rest is "ionized" calcium and this is freely available for biologic processes. Labs used to only be able to measure total calcium - calcium bound to Albumin + ionized. Now we can measure ionized calcium and not be mislead that calcium is low because Albumin is low. ...Read more

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Female 26- calcium 10.5 ionized calcium 1.34, is that normal?

Female 26- calcium 10.5 ionized calcium 1.34, is that normal?

Just watch it: This is at the upper limit of normal for most reference ranges, and these in turn are set up so that several percent of healthy people will fall on either side. Watch and see what it's like on your next routine set of labs unless you develop symptoms. ...Read more

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What's the difference between calcium and ionized calcium blood test? Thank you.

What's the difference between calcium and ionized calcium blood test? Thank you.

Basic chemistry: About half of the calcium in your blood is protein-bound, mostly to albumin, and therefore exerts no phsyiologic effect. The rest is the active form and is what is regulated and what matters. The ionized calcium can be estimated from a formula using albumin, or measured directly by a more difficult technique. Total calcium is easy to measure. ...Read more

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What does blood test of ionized calcium mean? What does it measure? What does it mean if the ionized calcium is below the normal range?

What does blood test of ionized calcium mean? What does it measure? What does it mean if the ionized calcium is below the normal range?

Can't tell: By itself any one blood test, normal or abnormal, means absolutely nothing unless there is some context. You can't determine the significance of this without knowing when it was drawn, why it was drawn, and whether there are any other abnormal tests. Sometimes it means absolutely nothing. Ask the doctor who drew it. ...Read more

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What does it mean when my IONIZED CALCIUM is LOW and my INTACT PTH is high? What's the cure to this alarming result? Please help. Thanks.

What does it mean when my IONIZED CALCIUM is LOW and my INTACT PTH is high? What's the cure to this alarming result? Please help. Thanks.

Low Ca highPTH: Calcium in our blood circulates in two forms. Bound to albumin. Unbound =ionized. Low ionized Calcium is low unbound calcium. It is abnormal. And low ionized calcium will trigger PTH secretoon to higher levels. Remedy requires figuring out why and fixing root cause. Meanwhile, under guidance, take vitamin D 2000 iu daily and 1000 mg calciun as calcium citrate. Is your kidney function normal? ...Read more

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With my slightly below normal IONIZED CALCIUM and slightly elevated INTACT PTH, is it beneficial to take 1 tablet of CALCIDAY once a day?

With my slightly below normal IONIZED CALCIUM and slightly elevated INTACT PTH, is it beneficial to take 1 tablet of CALCIDAY once a day?

Calcium: You should be taking in at least 1000 mg of calcium per day. Much of calcium is not absorbed. It may be important to determine whether you have a problem with calcium absorption. Vit D deficiency will do this. See your doctor about your Vit D level. ...Read more

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My ionized calcium es 1.22 is that low?

My ionized calcium es 1.22 is that low?

Don't think so.: Each lab report should have a reference range of "normal" values. The reference range changes from lab to lab because each lab runs their test differently. Automated (machine) analyzers tend to have less variability, and in most of those machines, an ionized calcium of 1.1 to1.2 Is about in the middle of the "reference range". ...Read more

Dr. Quresh Khairullah
507 doctors shared insights

Dialysis (Definition)

Simple answer is that it is a medical technology used primarily to provide an artificial replacement for lost kidney function in people with renal failure. Hemodialysis remove wastes and excess water from the blood by circulating blood outside the body through an external filter, called a dialyzer. Blood and dialysate flow through in opposite directions and the ...Read more