Doctor insights on:
Max Daily Dose Gabapentin
1200 mg 3-4x/day: Gabapentin is a peculiar medication. The absorption is not linear with the dosage. With each increase, you absorb less of the increase. 600 mg 8x/day is more than 1200 mg 4x/day I your body! This effect plateaus around 1200 mg per dose. However, that said, dosage limits are often reached symptomatically; ie, lethargy, sedation, tremor, trouble walking. Balance/coordination problems. ...Read more
Low dose Gabapentin unlocks permanently contracted muscles/fascia (?) in back, hips. Can stretch, squirm in exquisite novel ways. Is this spasticity?
I started on 300mg of Neurontin (gabapentin) for RLS its only been 3 days but does nothing for me. How long before it will help and what is the max dose?
I have small fiber neuropathy and I'm taking 900 mg of gabapentin for my foot pain. Not helping at all. What's the chance the max dose will help?
I take 3200mg of gabapentin daily (800mg x 4). If I forgot whether I took my dose & accidentally took 2 at one point, would that be a problem?
Sedation: Most likely you would be feel quite sedated, maybe dizzy as well. It could make it hard to function. Why not use a medication box in which you can set your meds up for the week-- this way you will know if you have taken your dose or not-- just take a look in the box. Spending 1 day a week filling in the box makes the rest of the week so much easier--you will thank me! ...Read more
I have very bad nerve pain in my feet caused by chemo. High daily doses of Neurontin (gabapentin) does not relieve the pain. Is there a surgical tx?
No: But ask your oncologist about some other medications that might help with the pain. ...Read more
Can I takeup to a 325 mg dose of a magnesium w/these daily medications? 20 mg viibryd, (vilazodone hydrochloride) 25 mg atenolol, 0.5 mg clonazepam, 100 mg gabapentin 50 mg tra
Yes: There are no contraindications with any medication, as far as I know. Magnesium is found in many foods, and magnesium deficiency has become more common, particularly with use of drugs like omeprazole (Prilosec), esomeprazole (Nexium) and similar drugs which markedly reduce stomach acid and impede magnesium absorption. ...Read more
What do you advise if I'm on 100 mg of gabapentin once a day at night is it okay to drink while taking this if I don't take the dose that night?
No: Gabapentin (Neurontin) is an anticonvulsant and analgesic drug. It was originally developed to treat epilepsy, and is currently also used to relieve neuropathic pain. It has been used "off-label" for many other conditions. Alcohol and gabapentin are dangerous when mixed together for a variety of reasons. ...Read more
Can I get advice? I've got a few questions: will the side-effects from the gabapentin subside with time, assuming I continue to take at current dose?
Normally with in a: Few weeks. Most people notice side affects disappearing around one to three weeks, if they are going to disappear. If they do not end by a month, then they often will stay around. If you are having problems with side effects, then ask doc if Pregabalin might be a better fit for you. ...Read more
I've been taking gabapentin for 2 months 300mg daily. I have lost my appetite & lost 15 pds. Is this a normal side effect? I have no other side effect
Depends: Adverse effects can unfortunately occur within an hour of a dose, but treatment benefit can take a couple of weeks to gauge. ...Read more
I just started Neurontin (gabapentin) 300mg & am supposed to increase to 900mg a day. How do I divide my dose?
Suggestions: Neurontin (gabapentin) or Gabapentin has a relatively short half-life and is best taken 3 times daily, about every 8 hrs. Maximum effective dose is about a total of 3600 mg daily. Slow titration done to allow fewer adverse reactions. Would suggest you first go to 300mg twice daily for 3 or 4 days and then 300 mg every 8 hrs. Do contact your doctor and get explicit directions as to how to proceed from there. ...Read more
Gabapentin worked for me 3 days ago, now it does nothing at all at any dose. Can tolerance build that quickly? How do I reverse tolerance?
No: Gabapentin is not prone to tolerance (aka tachyphylaxis). Usually the dose builds up in the system until at a therapeutic level. Once there it will not stop working abruptly (unless there is an interaction with another medication. If stopped it should be tapered slowly under your doctor's supervision. Stopping the medication for a time is the only way to reverse medication tolerance. ...Read more
Gabapentin worked for me for 2 days only, now it does nothing at all at any dose. Can tolerance build that quickly? How do I reverse tolerance?
Horizant: Gabapentin enacarbil gets around this problem by providing predictable even blood levels of gabapentin. Regular Gabapentin is unpredictably absorbed in the stomach whereas the enacarbil component of Horizant delays absorption until the small intestine where it is very predictably absorbed. ...Read more
Smaller doses of gabapentin better then higher doses? Bioavailability seems higher with lower doses so wouldn't you get more of the drug on lower dose
Gabapentin: True but at the same time you need a high dose of gabapentin in your system for it to work. Usually 1200mg. So lets say you take 300mg, and you absorb all 300... that's great but all you have is 300mg in your system. Now take 900mg. Lets say bioavailability fall to 75%. Well 75% of 900 is still way more in your system than 300mg. Oral absorbtion is generally like this. ...Read more
My Dr upped my Neurontin (gabapentin). I was on 300mg TID, now I'm on 300mg BID&600mg 1x day, total of 1, 200Mg QD. Can I take the new dose spaced out like 300MG QID?
Ask your doctor: My best answer is ask your doctor who prescribed you the Neurontin (gabapentin). In my experience, the typical daily dosing of this medication is three times a day. When the dosing frequency is increased, patients tend to miss their doses (compliance decreases). Talk to your doctor and discuss your thoughts. ...Read more
Possibly: Neurotin can be used for this purpose. ...Read more
I'm on small dose of methadone and dr. Gave me neurontin (gabapentin) for rls can I take them together?
Methadone/Neurontin: As prescribed, yes.Get a more detailed answer ›
What to do if I take 1200 mg of gabapentin twice daily and still have back pain. How much more can I take?
I think I accidentally doubled my dose of propranolol 20mg and Neurontin (gabapentin) 300mg for anxiety. Anything I should watch for? Thanks!
I take 300mg of gabapentin 3 times daily. Can I also take 0.25mg of Xanax (alprazolam) twice a day. Just started the gabapentin Interactions?
Is 100mg 3x/day enough gabapentin for serious headache relief? Seems like a very small dose, increasing from 100mg by adding one dose/week seems slow
It depends on the: Individual. Increasing the dose slowly may prevent side effects, you may want to discuss this with your physician. ...Read more
Is it possible to suddenly become allergic to medication I have been on daily for two years (100mg gabapentin) or is it something else cause allergy?
Unlikely: A 41 year old female on gabapentin for 2 years now having an allergic reaction. Unlikely to be due to the gabapentin now. If you had atopic dermatitis as a child, now a new skin rash could be a flare of atopic dermatitis or a new onset contact dermatitis to an exposure. Could also be an allergic reaction to something in the environment - insect bites, other irritants. ...Read more
No interaction: Since you are breastfeeding, question to ask is whether either the Ativan (lorazepam) and/or Gabapentin might enter the milk in any quantity. Usually, not a big issue. Since gabapentin has few if any drug-drug interactions, you should have minimal problems. But both could cause drowsiness and dizziness, and thus, additive side effects. ...Read more