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Doctor insights on: Matulane

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Dr. Lynne Weixel
6 doctors shared insights

Matulane (Overview)

Matulane is a cancer agent.


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Is matulane (procarbazine) just for treating lymphomas?

Is matulane (procarbazine) just for treating lymphomas?

Procarbazine is: The generic name, it is an old drug, it was one ofthe "p's" in the mopp regimen for hodgkin's lymphoma. The other "p" is prednisone, and now "platinum". Pcz was also used in brain tumors at one time, but rarely if ever any more. I hope this helps. ...Read more

Dr. Lynne Weixel
6 doctors shared insights

Matulane (Overview)

Matulane is a cancer agent.


2

2
Is matulane (procarbazine) just for treating lymphomas?

Procarbazine is: The generic name, it is an old drug, it was one ofthe "p's" in the mopp regimen for hodgkin's lymphoma. The other "p" is prednisone, and now "platinum". Pcz was also used in brain tumors at one time, but rarely if ever any more. I hope this helps. ...Read more

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Is matulane (procarbazine) useful to non-hodgkin's lymphomas?

Is matulane (procarbazine) useful to non-hodgkin's lymphomas?

No: Only indication is for hodkin's disease, and even in that condition, where it is used as part of the "mopp" regimen, it has been replaced by other regimens. It may have slight activity in other lymphomas but there are now many other effective chemotherapeutic and biologic choices. ...Read more

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Is it safe to take procarbazine while pregnant or breastfeeding?

Is it safe to take procarbazine while pregnant or breastfeeding?

Not recommeded: This is a medication that has some clear issues, especially early in pregnancy and with breast feeding. It can cause abnormalities of the feet, kidneys and the heart if you take it in the first 14 weeks. If you are on this medication, you should talk to your doctor before you get pregnant about coming off. In the second or third trimester, you should talk about if the benefits outweight risks. ...Read more

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Why has the drug temozolomide replaced the combination of procarbazine, carmustine and vincristine?

Why has the drug temozolomide replaced the combination of procarbazine, carmustine and vincristine?

Newer treatment: In treatment of Cancer, newer drugs come along and are then compared to the standard(old/conventional treatments). If the new treatment if better(more effective or less toxic) then the new drug takes over and the older drugs put on the back burner. That is what has happened in this instance. This is what has happened in the treatment of brain tumors. ...Read more

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Diagnoged with cutaneous tcell lymphoma .Treated with eletron beam.Interferon, gemcitabine, anthracycline, etoposide, procarbazine without improv.I'm 64 y?

Diagnoged with cutaneous tcell lymphoma .Treated with eletron beam.Interferon, gemcitabine, anthracycline, etoposide, procarbazine without improv.I'm 64 y?

There are new agents: There are several new agents for this disease. It is uncommon and you need a good assessment of the status of both your disease and your ability to take treatment. There are oral agents, antibodies, drugs like velcade (bortezomib) that might be helpful. I would suggest an evaluation by an oncologist who is familiar with this disease. ...Read more

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Dr. Mark Pack
12 doctors shared insights

Procarbazine (Definition)

Procarbazine ...Read more