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Doctor insights on: Matulane

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Dr. Daniel Saurborn
6 doctors shared insights

Matulane (Overview)

Matulane is a cancer agent.


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Is matulane (procarbazine) just for treating lymphomas?

Is matulane (procarbazine) just for treating lymphomas?

Procarbazine is: The generic name, it is an old drug, it was one ofthe "p's" in the mopp regimen for hodgkin's lymphoma. The other "p" is prednisone, and now "platinum". Pcz was also used in brain tumors at one time, but rarely if ever any more. I hope this helps. ...Read more

Dr. Daniel Saurborn
6 doctors shared insights

Matulane (Overview)

Matulane is a cancer agent.


2

2
Is matulane (procarbazine) just for treating lymphomas?

Procarbazine is: The generic name, it is an old drug, it was one ofthe "p's" in the mopp regimen for hodgkin's lymphoma. The other "p" is prednisone, and now "platinum". Pcz was also used in brain tumors at one time, but rarely if ever any more. I hope this helps. ...Read more

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Is matulane (procarbazine) useful to non-hodgkin's lymphomas?

Is matulane (procarbazine) useful to non-hodgkin's lymphomas?

No: Only indication is for hodkin's disease, and even in that condition, where it is used as part of the "mopp" regimen, it has been replaced by other regimens. It may have slight activity in other lymphomas but there are now many other effective chemotherapeutic and biologic choices. ...Read more

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Is it safe to take procarbazine while pregnant or breastfeeding?

Is it safe to take procarbazine while pregnant or breastfeeding?

Not recommeded: This is a medication that has some clear issues, especially early in pregnancy and with breast feeding. It can cause abnormalities of the feet, kidneys and the heart if you take it in the first 14 weeks. If you are on this medication, you should talk to your doctor before you get pregnant about coming off. In the second or third trimester, you should talk about if the benefits outweight risks. ...Read more

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Why has the drug temozolomide replaced the combination of procarbazine, carmustine and vincristine?

Why has the drug temozolomide replaced the combination of procarbazine, carmustine and vincristine?

Newer treatment: In treatment of Cancer, newer drugs come along and are then compared to the standard(old/conventional treatments). If the new treatment if better(more effective or less toxic) then the new drug takes over and the older drugs put on the back burner. That is what has happened in this instance. This is what has happened in the treatment of brain tumors. ...Read more

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Diagnoged with cutaneous tcell lymphoma .Treated with eletron beam.Interferon, gemcitabine, anthracycline, etoposide, procarbazine without improv.I'm 64 y?

Diagnoged with cutaneous tcell lymphoma .Treated with eletron beam.Interferon, gemcitabine, anthracycline, etoposide, procarbazine without improv.I'm 64 y?

There are new agents: There are several new agents for this disease. It is uncommon and you need a good assessment of the status of both your disease and your ability to take treatment. There are oral agents, antibodies, drugs like velcade (bortezomib) that might be helpful. I would suggest an evaluation by an oncologist who is familiar with this disease. ...Read more

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Diagnoged with cutaneous tcell lymphoma nhl.Treated with eletron beam.Interferon, gemcitabine, anthracycline, etoposide, procarbazine.Nodules over body .?

There are: Several new therapies which have come to market in the us. Not sure about india. We also use extracorporeal photopheresis, but that requires a specific machine and a photochemical called uvadex (methoxsalen). ...Read more

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Am I dying?

Am I dying?

We all are: A 3-word question with no details... well, life is short on Earth, regardless of whether a person lives 3 days, 3000 days, or 30,000 days. It is not length of one's life that matters, but the quality of the life lived. The goal is not to live a long life, but to live a good life. Even if a person makes it all the way to age 82, that's only 30,000 days. ...Read more

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I have cold?

I have cold?

Symptoms?: The most common symptoms of a cold are sneezing, running nose, congestion and scratchy throat. Additional symptoms can be coughing, headaches, mucus dripping down the back of the throat, loss of appetite and fever (in children). ...Read more

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What is asp?

What is asp?

In acupuncture an: Asp is an acupuncture semi-permanent needle. They are made in germany & come in stainless steel, gold, silver & titanium. They are used for auricular (ear) acupuncture. They are usually referred to as "asp's". ...Read more

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Dr. Jan Lei Iwata
12 doctors shared insights

Procarbazine (Definition)

Procarbazine ...Read more