Doctor insights on:
No: Only indication is for hodkin's disease, and even in that condition, where it is used as part of the "mopp" regimen, it has been replaced by other regimens. It may have slight activity in other lymphomas but there are now many other effective chemotherapeutic and biologic choices. ...Read more
Not recommeded: This is a medication that has some clear issues, especially early in pregnancy and with breast feeding. It can cause abnormalities of the feet, kidneys and the heart if you take it in the first 14 weeks. If you are on this medication, you should talk to your doctor before you get pregnant about coming off. In the second or third trimester, you should talk about if the benefits outweight risks. ...Read moreSee 1 more doctor answer
Why has the drug temozolomide replaced the combination of procarbazine, carmustine and vincristine?
Newer treatment: In treatment of Cancer, newer drugs come along and are then compared to the standard(old/conventional treatments). If the new treatment if better(more effective or less toxic) then the new drug takes over and the older drugs put on the back burner. That is what has happened in this instance. This is what has happened in the treatment of brain tumors. ...Read more
Diagnoged with cutaneous tcell lymphoma .Treated with eletron beam.Interferon, gemcitabine, anthracycline, etoposide, procarbazine without improv.I'm 64 y?
There are new agents: There are several new agents for this disease. It is uncommon and you need a good assessment of the status of both your disease and your ability to take treatment. There are oral agents, antibodies, drugs like velcade (bortezomib) that might be helpful. I would suggest an evaluation by an oncologist who is familiar with this disease. ...Read moreSee 1 more doctor answer