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Doctor insights on: Mast Cell

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Mast Cell (Overview)

Innate immune cell prevalent in tissue and surrounding small blood vessels. Acts as a source of histamine and other rapid acting mediators of an inflammatory response to tissue infection or damage. Inappropriate activation of mast cells is central to many allergy-related diseases including anaphylaxis. Inappropriate population expansion or activity results in mast cell activation disorders


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What is nonclonal mast cell activation disorder?

What is nonclonal mast cell activation disorder?

Newly characterized: It's a mimic for disorders caused by a neoplastic clone of mast cells. This is hematology subspecialist stuff and i would much rather have this than one of the clonal forms. http://www.ncbi.nlm.nih.gov/pubmed/23212667. ...Read more

Mast Cell (Overview)

Innate immune cell prevalent in tissue and surrounding small blood vessels. Acts as a source of histamine and other rapid acting mediators of an inflammatory response to tissue infection or damage. Inappropriate activation of mast cells is central to many allergy-related diseases including anaphylaxis. Inappropriate population expansion or activity results in mast cell activation disorders


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What is the definition or description of: mast cell?

Mast cell: Innate immune cell prevalent in tissue and surrounding small blood vessels. Acts as a source of histamine and other rapid acting mediators of an inflammatory response to tissue infection or damage. Inappropriate activation of mast cells is central to many allergy-related diseases including anaphylaxis. Inappropriate population expansion or activity results in mast cell activation disorders ...Read more

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Living with Sickle Cell Disease (Checklist)

Keep doctor's appointments
Once
Go to lab appointments
Once
Keep oxygen up by maintaining low weight, no smoking
Once
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What can you tell me about the diagnosis of Mast Cell Activation Syndrome?

What can you tell me about the diagnosis of Mast Cell Activation Syndrome?

MCAS: Mast Cell Activation Syndrome is a condition with signs ans symptoms involving the skin,gastrointestinal,cardiovascular,respiratory,and neurologic systems. It can be classified into primary,secondary and idiopathic . show episodic symptoms consistent with mast cell mediator release affecting two or more organ systems with urticaria,angioedema,flushing ,nausea,vomiting,diarrhea, abdominal cramping' ...Read more

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How can you be checked for a mast cell disorder or disease. Like mastcytosis or mcad? Is there a certain test that can verify or rule it out?

Biopsy: Biopsy looking for increased mast cells is the best way . One will also measure tryptase levels and other mediators in the blood. The organ to be biopsied depends on the spectrum of disease. There are some physical signs as well. Would see an allergist or a gastroenterologist who has some knowledge of this disease process. If localized to the skin a dermatologist might be of help. Bone marrow ? ...Read more

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Are there any cures for mast cell disease?

Usually not: In rare cases where it is due to a leukemia or related illness, curing or managing this works well, and some folks respond to gleevec (imatinib). Otherwise, we're left managing the symptoms, which is usually possible. I have a colleague with mastocytosis under quite good control, and there are support groups in communities and online. Good luck, and stay proactive. ...Read more

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Can toothache trigger mast cell activation?

Can toothache trigger mast cell activation?

Allergic reaction: Mast cells are activated during allergic reactions and in some autoimmune diseases. A toothache is a infection and not an allergic reaction so here would be few mast cells. ...Read more

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Are mast cell tumors people tumors or dog tumors?

Are mast cell tumors people tumors or dog tumors?

I know humans: I don't know about dogs, but humans can get systemic mastocytosis. An uncommon clonal growth of mast cells. Mast cells may also be reactive, such as from allergies. ...Read more

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My husband was diagnosed with mast cell disease. Can anyone help?

My husband was diagnosed with mast cell disease. Can anyone help?

Need to see a doctor: Your husband need to follow-up with the doctor who made that diagnose. ...Read more