Doctor insights on:
Marfan Affect My Children
50% for each child: Marfan syndrome is caused by a mutation of the fbn1 gene on chromosome 15. An affected man (or woman) has one normal and one mutant fbn1 gene in each of his (or her) cells. For each of his children, the chance that he will pass on the mutation is 1/2 or 50%. This pattern of inheritance is called autosomal dominant. ...Read more
Marfan's syndrome is a genetic disorder caused by defects in a protein called fibrillin that, along with collagen, provides most of the structural support of our tissues. Individuals with Marfan's are often tall, lanky, have long arm spans, and are hyperflexible. The most serious complication of Marfan's is caused by defects in the wall of the aorta, the large blood vessel that leaves the heart and supplies the ...Read more
I think I have Marfan syndrome, but i'm not sure if I want to go get checked. Will it affect insurance?
Unknown: The new health care law says that insurers cannot deny insurance for "preexisting conditions". So if this health care law stays in place it will not be a problem. No matter what, if you may have marfan's you need to have it confirmed, and if positive see a cardiologist. With good care, pts with marfan's can have normal lifespan. Without care they can have cardiac problems. ...Read moreSee 1 more doctor answer
Unrelated: The two are completely unrelated, you should consider them separately, and not worry about how one condition will affect the other. ...Read more
Lens dislocation: The most common problem is that the lenses in the eyes are held in place by zonules. These are weakened by this syndrome and frequently the lenses can be come partially/totally dislocated causing blurred vision or other problems within the eyes. See an ophthalmologist. ...Read moreSee 1 more doctor answer
Marfan's syndrome: It is a broad topic. Difficult to cover here. Please refer to the site: http://en.Wikipedia.Org/wiki/marfan_syndrome. ...Read more
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