Doctor insights on:
Mantle Cell Lymphoma Life Expectancy
Mantle cell: Lymphoma has a broad range of expected survival. The minority of patients have an indolent course, and may not even require therapy at the time of diagnosis. More commonly treatment is initiated with moderate to aggressive chemotherapy with duration of benefit on the order of 3-5 years. With recurrence the management can be more challenging. ...Read moreSee 1 more doctor answer
Stage ?: Depends on stage. There are two subsets of mantle cell nhl. One is an indolent subset in which 5 yr survival approaches 70-80%. The othe more aggressive subset has a prognosis of only 50/50 at three years. But stage also matters. ...Read more
Non hodgkin's: Mantle cell lymphoma is a subset of non hodgkin's lymphoma. Under microscope, it looks like clusters of small size of lymphoid cells mimicking appearance of indolent/slow-progressing lymphoma, however it behaves like an agressive lymphoma. The treatment would be combinations of chemotherapies plus biological therapy. ...Read moreSee 1 more doctor answer
Mantle cell lymphoma: Is a less common b-cell disease in the non-hodgkin's lymphoma group. It tends to be advanced stage when diagnosed, and can have a propensity to involve both the gut and skin. About 20% of cases behave indolently, and treatment is quite effective at diagnosis. Late relapses are common, and treatment is more challenging the second time around. ...Read moreSee 1 more doctor answer
Months, anywhere: Mantle cell lymphoma is a rare subtype of non-hodgkin's lymphoma. It usually grows relatively slowly and might take several weeks to a few months to develop. It most commonly presents in the lymph nodes, the blood, and the spleen although it can also present anywhere in the G.I. Tract from the stomach down to the colon. ...Read moreSee 1 more doctor answer
Go to ER now!!: BP of 70/40 is very abnormal. You should check whether the machine is accurate-make sure the cuff placement is correct. If it is confirmed, you absolutely should bring your mother to er now. She may be severely dehydrated or other condition that perhaps related or unrelated to her mantle cell lymphoma . Bring her to er now. ...Read more
What type of nodes would appear with mantle cell lymphoma or any other type of malignancy? Would they be rigid and fixed or can they be soft and moveable? Internist felt node but said likely benign.
Lymph node: Generally malignant lymph nodes are firm, but I have seen some that were soft and movable. If this node doesn't recede within a week or so, and if new enlarged nodes appear a biopsy would seem advisable. Discuss this with your physician and he/she will advise you about what type of follow-up is best. ...Read more
Serious: Mantle cell lymphoma is a serious type of non-hodgkin lymphoma. In a younger patient under the age of 70 and otherwise in good health it can be put into remission for several years with chemotherapy and stem cell transplantation. In older patients or patients who are otherwise sick there are some treatments i can put the disease into remission for a few years. ...Read moreSee 1 more doctor answer
Mantle Cell Lymphoma: ...is a type of non Hodgkin's lymphoma characterized by the genetic rearrangement of two chromosomes. This causes an abnormal fusion of two genes: Immunoglobulin (IgH) and Cyclin D1. Molecular studies that can detect this abnormality includes either FISH or RT-PCR. Flow cytometry is also good at identifying abnormal cells based on cell surface antigen expression. ...Read more
My mother just passed away from mantle cell lymphoma, what might have caused her to act so strange at the end?
Many causes: My condolences on your loss. There are many reasons for confusion and delirium at the end of life. Mantle cell lymphoma specifically can sometimes go to the brain of a patient although this is quite rare. It is much more likely that either her discomfort or the medications that she was on to keep her comfortable made her somewhat confused. ...Read moreSee 1 more doctor answer
Any known treatments for late onset neutropenia due to rituximab. The R was being used for mantle cell lymphoma maintenance. Thanks.
May not be needed: This doesn't always require treatment. If you have an active severe infection or neutropenia is severe then it can be treated with neupogen. If you don't have an infection or very severe problem it is best left alone. Try to be careful about staying away from other people who are sick and wash your hands frequently. ...Read more
Best first-line treatment for mantle cell lymphoma now: high doses of ara-c+rituximab and autologous sc transplant, or rituximab+bendamustine?
There is no: Definitive answer to your question. Studies have compared the strategies you mention. The high dose ara-c arm was closed because it was difficult to mobilize stem cells for transplant after these regimens. Bendamustine-r is a good program, and many centers would consolidate a good response with an autograft. ...Read more
My grandpa just got dx with mantle cell lymphoma by biopsy 82y/o. bone marrow biopsy & pet scan not back. Prognosis & treatment? Is it genetic?
?????: The better question would be: why in God's creation would someone not get treated for a highly curable disease like Hodkin's disease? I am not even sure that an accurate answer to your question is possible to come up with. Ultimately it would cause death but how long it would take? Cannot tell. ...Read more
Depends: There are many factors that effect life expectancy including the patients underlying health and the stage of lymphoma. For example lymphoma that is slower growing and has not spread is a better case than a lymphoma that is aggressive and has spread to multiple organs. Hard to answer that question without more information. ...Read moreSee 1 more doctor answer
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