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Doctor insights on: Mantle Cell Lymphoma Bcl 1 Jh Pcr

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Polymerase Chain Reaction (Definition)

Polymerase chain reaction is a method of finding a specific piece of dna and copying it over and over again until there is enough to study. The technique allows a scientist to detect very small amounts of dna in a swab sample then reproduce enough of it to study it. It is very sensisitive for detecting the presence of certain bacteria and is also used in doing other ...Read more


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Survival rate for triple neg receptors for early stage breast cancer after chemo treatment? No lymph nodes involve, stage 1b, grade 2, mastec done

Survival rate for triple neg receptors for early stage breast cancer after chemo treatment?  No lymph nodes involve, stage 1b, grade 2, mastec done

Excellent: According to adjuvant online (www.Adjuvantonline.Com), you have about an 82% 10 yr survival rate based on your specific information provided. This is only an estimate since there are details I do not have such as type of chemotherapy being used. For triple negative breast cancer, these survival rates are quite excellent. ...Read more

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Stage 4 non hodgkin's lymphoma 10 year survival rate?

Stage 4 non hodgkin's lymphoma 10 year survival rate?

Still good prognosis: Survival rates for nhl vary widely, depending on the lymphoma type, stage, age of the patient, and other variables. The overall 5-year relative survival rate for patients with non-hodgkin’s lymphoma is 63% and the 10-year relative survival rate is 51%. All the best, hk. ...Read more

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Can stage 1a endometrial cancer (removed) spread to mediastinal, bilateral hilar and virchow's node w/o infiltrating another organ?

Can stage 1a endometrial cancer (removed) spread to mediastinal, bilateral hilar and virchow's node w/o infiltrating another organ?

Yes but: It could possibly spread to local lymph node but the chances are very low. The lymph nodes that are in thoracic cavity are even less likely to contain metastatic tumor from a stage 1a endometrial cancer, especially if it's a garden variety low grade lesion. In fact, long term survival is very good, like 95%. The other 5% may represent very high grade tumors. ...Read more

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What risk assessments tests to do with smoldering multiple myloma pls tel me is it smoldering myloma when m spike is below 1 but 14 percent plasma cel?

What risk assessments tests to do with smoldering multiple myloma pls tel me is it smoldering myloma when m spike is below 1 but 14 percent plasma cel?

Regular follow-up: Smoldering myeloma is a pre-malignant condition with about 10% people developing myeloma/year. You correctly defined your condition as smoldering myeloma. There is need to do repeated blood tests every 6-12 months. Please follow you doctor's advice. ...Read more

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Oral sex with unknown, continuous 5month low grade fever, lymph nodes, sore throat, 107 da HIV eia negative HIV PCR RNA not detected, what other std?

Oral sex with unknown, continuous 5month low grade fever, lymph nodes, sore throat, 107 da HIV eia negative HIV PCR RNA not detected, what other std?

NOT STD: As you have been told this is not an STD. But, it could be an infectious disease. That list is hundreds of possibilities long and will include testing for lymphoma, leukemia, other blood cell cancers, and all of the possible non-STD infectious diseases. It is time to sign off of the internet and to see your doctor for the appropriate testing or infectious disease consultation. ...Read more

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Is bone marrow transplantation is curative for chronic myeloid leukemia caused by (Philadelphia chromosome) ?

Is bone marrow transplantation is curative for chronic myeloid leukemia caused by (Philadelphia chromosome) ?

Yes: In 70 to 80 percent of cases. The availability of tyrosine kinase inhibitors such as gleevec (imatinib) has moved transplant to 3rd line treatment ...Read more

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What is an inhomogenous spleen in hodgkin's lymphoma?

What is an inhomogenous spleen in hodgkin's lymphoma?

An homogenous: You mean a scan report an homogenous spleen in hodgkins lymphoma ? Then it is a normal spleen , the disease did not involve the spleen, good news. ...Read more

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CML 10/12. Gleevec .5 log at 6 mths. Sprycel (dasatinib) .5 log at 6 mths. Stem cell transplant 4/14. 7/14 Blast crisis - 65% blast BM + Aspergillus F lung Help?

CML 10/12. Gleevec .5 log at 6 mths. Sprycel (dasatinib) .5 log at 6 mths. Stem cell transplant 4/14.  7/14 Blast crisis - 65% blast BM + Aspergillus F lung Help?

Difficult case: it is a complicated case obviously. first and foremost the infection has to be treated. i would suggest you to follow up with ID and oncologist very closely. importantly is to check if there is certain mutation like T315i mutation as this mutation is resistant to gleevec, sprycel, tasigna (nilotinib) - and should be treated with ponatinib or aurora kinase inhibitor etc. discuss with oncologist. God bless ...Read more

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Solitary, solid nodule with intranodular flow and follicular neoplasm cells. Afirma came back suspicious. What's likelyhood of malignancy?

Solitary, solid nodule with intranodular  flow and follicular neoplasm cells. Afirma came back suspicious. What's likelyhood of malignancy?

Ask your doctor: The doctor who ordered your biopsy has responsibility to explain to you the meaning of the results. If the biopsy shows neoplastic cells, that usually means Cancer cells. But you should get this clarification from your doctor. ...Read more

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What is the difference between: basal cell carcinoma epithelioma, squamous cell carcinoma, and melanoma?

Skin cancer: The difference between basal cell carcinoma, squamous cell carcinoma, and melanoma has to do with how the skin cancer cells appear under the microscope as well as how they behave. Therefore it is important that they be diagnosed and treated as quickly as possible by a healthcare professional who specializes in this area. ...Read more

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Mcv 69.6(L) rdw cv 22.2(H) platelets 415(H) neutrophils 28(L) lymphocytes 60.6(H) abs neutrophils 2.6(L) anisocytosis (marked) ovalocytes (slight) 11m?

Mcv 69.6(L) rdw cv 22.2(H) platelets 415(H) neutrophils 28(L) lymphocytes 60.6(H) abs neutrophils 2.6(L) anisocytosis (marked) ovalocytes (slight) 11m?

Is this new?: If your previous CBC's have been okay, I'd address whether you are iron deficient (which seems likely) and if so why (your physician can address this with you), follow the very mild neutropenia (not a danger yet) and since the anisocytosis is marked, ask whether the lab's pathologist might be good enough to look at the smear. ...Read more

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For 58+ F, Hb 10.8, RBC 3.66, PCV 34, MCV 94, MCHC 31, WBC 5.4, Pt 1.8, Iron 57, TIBC 255, TSI 22, RC 1.2, Ferritin 83 indicate which type of anemia ?

For 58+ F, Hb 10.8, RBC 3.66, PCV 34, MCV 94, MCHC 31, WBC 5.4, Pt 1.8, Iron 57, TIBC 255, TSI 22, RC 1.2, Ferritin 83 indicate which type of anemia ?

Mild anemia: Assuming you've had no recent bleeding episodes, these findings could be seen in mild/early anemia of chronic disease. Hgb and Hct are only boarder line low, and iron panel appears within the reference range. Even something as simple as a particularly heavy period could cause mild anemia of this type, though. If you have a chronic medical illness, it could cause this type of anemia. ...Read more

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I'm hebs ag negative with a high anti hbs antibody from vaccination. This week's test was reported as hebs ag detected with anti hbs antibody of 513 miu/ml. Lft normal....Scared....Lab error?

I'm hebs ag negative with a high anti hbs antibody from vaccination.  This week's test was reported as hebs ag detected with anti hbs antibody of 513 miu/ml. Lft normal....Scared....Lab error?

Yes: That sounds like lab error. Your hbsab would provide immunity; i'm assuming yoru hbcab (core) is negative; i wouldn't worry, talk to your doctor about a retest if you are concerned, but even if you were infected, there is no reason for treatment at this time. ...Read more

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Been diagnosed with peripheral neuropathy blood test showed high immunoglobulin m w/polyclonal gammopathy. Kappa/lambda increase. Possible meaning?

Been diagnosed with peripheral neuropathy   blood test showed high immunoglobulin m w/polyclonal gammopathy. Kappa/lambda increase. Possible meaning?

PlasmaCellDIsorder: May have plasma cell disorder/multiple myeloma. Plasma cells are a type of white blood cells that produces immunoglobulin(antibodies). Multiple myeloma is a cancerous or excessive proliferation of these plasma cells which may lead to excessive high levels of calcium/bone pain/renal failure/anemia (low blood counts). Need to see hematologist (blood doctor specialist). ...Read more

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Is low WBC common 16 days after ivig? Wbc 2.7; abs neut .62; %'s seg23; lymph60; eosin7. History - WBC 3.5; abs neut 2.6; %'s seg74; lymph15; eosin 0

Is low WBC common 16 days after ivig? Wbc 2.7; abs neut .62; %'s seg23; lymph60; eosin7. History - WBC 3.5; abs neut 2.6; %'s seg74; lymph15; eosin 0

Possibly, : Neutropenia could be one of the complications, with some risks fir infection, however low. Talk to your immunologist or pcp. Thus article may help some what..., http://www.Ncbi.Nlm.Nih.Gov/m/pubmed/14646610/. ...Read more

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Wbc 13.2 RBC 4.73 hemoglobin 10.2 hematocrit 33.8 mvc 72 MCH 21.6 mchc 30.2 RDW 16.2 platelets 816, 000.Thoughts?Should i be worried with the platelets

Wbc 13.2 RBC 4.73 hemoglobin 10.2 hematocrit 33.8 mvc 72 MCH 21.6 mchc 30.2 RDW 16.2 platelets 816, 000.Thoughts?Should i be worried with the platelets

Probably reactive: You are anemic and the numbers are suspicious for iron deficiency. If you are a healthy 34 year-old who menstruates regularly, you could easily be low in iron. The plaelet count is very high, but is likely reacting to the low iron and should come down if it is replaced. The elevated white cells (WBC) is not as easy to understand. Inflamation, infection, other? Could use more info. Good luck. ...Read more

Pcr (Definition)

Polymerase chain reaction is used in molecular biology to amplify copies of dna. It is used in dna cloning for sequencing, functional analysis of genes, identification of genetic finger prints, diagnosis of hereditary ...Read more


Dr. Michael Thompson
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Lymphoma (Definition)

A malignancy developing in the lymphocytes of lymph glands. They present as an enlarging node that continues to grow and then ...Read more