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Doctor insights on:
Mannose Binding Lectin Deficiency Treatment
1
Is there any treatment to reverse mannose binding lectin deficiency?
Experimental: But intravenous infusion of purified mannose-binding lectin from a donor plasma is being used. ...Read more
2
Can taking bovine colostrum increase plasma immunoglobulin levels, thereby masking an underlying immunoglobulin deficiency by altering blood tests?
Unlikely: Very thoughtful idea. Unfortunately, the bovine immunoglobins are too large to be absorbed from the intestine and would be digested by stomach and intestinal juices and enzymes. With use you would be providing body with raw materials for making your own immunoglobulins, but at a cost. Any "complete" proteins from eggs or milk could provide the same protein precursors and support good health. ...Read more
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3
Serum b12> 1999 mma 0.4, homocysteine high 19. No folate (folic acid) or iron deficiency normocytic anemia not responding to procrit. Is this an absorption issue?
Anemia: can be caused by blood loss or bone marrow suppression as well. More information is needed ( how long have you had a normal iron, folate (folic acid) and b12 level. What is your reticulocyte count ? ( is your bone marrow producing new RBC's) ? How low is your HCT and has it come up or gone down with B12. Is the RDW elevated ( do you put out large and small RBC's at the same time? Any blood loss ? ...Read more
4
After iron supplement course iron is 48 MCV is 75 .4 and pcv is 33.7 and hemoglobin is 420... Y?
Numbers are unclear: Re submit labs.
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5
If vaccinations don't raise a mannose binding lectin deficiency, what is the next step?
Mannose binding: This genetic immune deficiency disorder makes people prone to recurrent infections such as uri, pneumonia and meningitis. Depending on the type of infection, the symptoms caused by the infections vary in frequency and severity. Unaware that vaccinations affect this in any way. ...Read more
6
Vitamin d deficient, 25hydroxy test result 5.8. What brand supplement and dosage is recommended?
Vitamin D3: Any brand will do. If you have access to Costco, buy pills of 5000 units and take one every day for three months. After that reduce the dose to about 2000 units/day. it may be beneficial to add a multivitamin to your daily routine. For good health - Have a diet rich in fresh vegetables, fruits, whole grains, low fat milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco or alcohol in any form. Practice safe sex. ...Read more
7
Why we treat megaloblastic anemia caused by vitamin B12 deficiency with folates (folic acid)?
We don't: Megaloblastic anemia caused by B12 deficiency is treated with b12. Folate (folic acid) deficiency also causes meg. Anemia. Some with B12 deficiency are also deficient in b12, but if one has low B12 ; isn't deficient in folate (folic acid) there's no need to supplement with it. But it won't hurt to take folate (folic acid);if you're among the 1/3 of people with problems converting Folic Acid to it's active form you should take l-5-mthf. ...Read more
8
Would ivig be considered in mannose-binding lectin deficiency, very low igm, igg3 and igg4 after no response to vaccines?
Yes: Mannose-binding lectin deficiency is a complement disorder. Low igm and subclass igg (in your case 3 ; 4) is a separate entity. With low immunoglobulins and no response to vaccines, ivig would be reasonable. See an immunologist to evaluate this. ...Read more
9
What micromineral deficiency can interfere with vitamin a metabolism by reducing retinol binding protein?
Carotene and others: Many proteins, and enzymes are involved in vitamin a metabolism. Some proteins are involved in creating the useful form of vitamin a into 11-cis-retina from vitamin a or b-carotene, which is useful in vision. Some proteins transport vitamin a , such as retinol binding protein. Many nutrients important such as zinc, lipids, carotenes. Age related eye study vitamins: ww.Areds2.Org. ...Read more
10
Is high RBC folate (folic acid) associated with vitamin B12 deficiency?
Not likely: Please consult this site for info in this topic. Folate (folic acid) and B12 are needed for efficient red cell production and other functions, but lack of one does not increase the other. http://www.webmd.com/diet/folic-acid. ...Read more
11
Is zinc gluconate an effective supplement for zinc deficiency? If not, what zinc supplement is best absorbed? Zinc Oratate? Acetate, picolinate?
Actually: I prefer Zinc Sulphate!! HOWEVER any of the above are most likely just fine since the amount needed to replenish your total body zinc is quite low!! (Higher levels are used in medical conditions eg cold virus control and Prostate function! ...Read more
12
19 moth old ferritin 7(2-291), iron 61(40-100) iron binding capcity unsat 470(110-370), total iron binding capcity 531(228-428) transferrin%sat 11(15-57?
Iron deficiecy...: With or without anemia. Talk to pediatrician about possible causes and rx. ...Read more
13
Is fefol (iron & folate (folic acid) supplement) 30 delayed release capsules suggested for anemia?
Anemia: If your doctor put you on it, yes it is suggested for anemia. Make sure you did se your docotr and your had blood tests that made the diagnosis of the deficiency. ...Read more
14
What can a very low level of mannan/mannose binding lectin mean?
Could: Be seen with immune deficiency, or it could be hereditary. May predispose person to certain infections. ...Read more
15
Is there signifance to folate (folic acid) level > 24 ng/ml and a vit B12 level of 343 pg/ml for someone with continuing fatigue? Fyi vit d =38 and ferritin=39.
Need more info: The labs you mention are normal. The significance is that your fatigue is not explained by b12, d, iron, or folate (folic acid) deficiencies. ...Read more
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16
Which form of zinc is better? Gluconate, picolinate, L-monomethionine zinc aspartate. Other?
Zinc Oxide and other: Preparations include zinc oxide, zinc acetate, and zinc gluconate. [135] It is believed to possess antioxidant properties, which may protect against accelerated aging of the skin and muscles of the body; studies differ as to its effectiveness. See attached for more details. ...Read more
17
Which is better for chronic anemia
1) ferrous gloconate
2) ferrous fumarate
As a supplements for iron deficiency?
Determine the cause: Chronic anemia does not equate to iron deficiency anemia. If you have been found to have iron deficiency anemia, however, there is no real superior supplement. They can be tolerated differently in different people. The most important thing is that you find one that does not bother your stomach, so that you can take it as recommended. ...Read more
18
Which supplement is best for magnesium deficiency?
Depends: There are many forms of magnesium on the market. Magnesium citrate if easy to find and relatively inexpensive. For more information, see: Http://drfairchild.blogspot.com/2012/12/magnesium.html ...Read more
19
Found out unknown cause folate deficiency-rX 5mg folic acid tabs,how long before replenished? When to retest? Causes ?VIT D borderline deficient too
Folate (folic acid) deficiency : Folate (folic acid) deficiency can be caused by nutritional deficiency, medications, chronic diseases or frequent use of tanning beds. 5mg of folate (folic acid) is often used to treat deficiency. Usually 4 months of treatment is needed, then dose can be reduced. Levels may be rechecked after 2 a 4 months. ...Read more
20
Is magnesium needed for vitamin D absorbtion as cofactor?
Magnesium is not: needed for absorption of D but it is good for muscle cramps, aches, and headaches. D is is needed as a co-factor for absorption of calcium, which is what you may be thinking of. Peace and good health. ...Read more
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