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Doctor insights on: Mannitol Medication

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Why is a person with increased intracranial pressure given the drug mannitol?

Why is a person with increased intracranial pressure given the drug mannitol?

Decrease pressure: Mannitol is used to manipulate osmotic (or oncotic) forces to shift water from the tissue into the blood vessels. In the kidney, mannitol increases water excretion. So, in patients with increased intracranial pressure, the intent is to decrease the pressure by using mannitol to "pull" fluid out of the brain and then excrete it via the kidneys. ...Read more

Dr. Amrita Dosanjh
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Can mannitol be used as a sweetener?

Can mannitol be used as a sweetener?

Yes: Mannitol can be used as a sweetener and it does not promote tooth decay. ...Read more

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Is mannitol in any foods or sugarless candies?

Is mannitol in any foods or sugarless candies?

Yes: Mannitol is used as a reduced-calorie sweetener and as a dusting powder (it doesn't pick up moisture from the air) in food, particularly sugarless food, candy, gum, & chewable tablets. ...Read more

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What is the debate regarding aspartame, sorbitol and mannitol?

What is the debate regarding aspartame, sorbitol and mannitol?

No: Some will accelerate the GI tract motility causing diarrhea, but most sugar-alcohols are great diabetic substitute sweetener. They are less sweet than sugar, and artificial sweeteners are much sweeter. They do stimulate insulin, but less than glucose. Aspartmae is an artifical sweetener. ...Read more

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Are the sugars in mannitol and malitol bad for your teeth?

Are the sugars in mannitol and malitol bad for your teeth?

Yes: Unfortunately erythritol, isomalt, sorbitol, and mannitol are recognized as a sugar source by the bacteria in our mouths and can cause cavities. Xylitol is the only sweetener that cannot be digested by oral bacteria. Chewed in small amounts (one or two pieces a day) xylitol can remineralize teeth. Gum with recaldent can also remineraize your teeth. ...Read more

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What effect will mannitol have on kidney function?

What effect will mannitol have on kidney function?

Diuretic: Manitol is a sugar like substance which is filtered by the kidney and not reabsorved like glucose would so it remains in the kidney tubules and it acts as a urine volume enhancer by pulling water and electrolytes into the urine space and ultimately out in the urine so as to be an osmotic diuretic. It is used mainly to reduce brain edema acutely. ...Read more

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Can I take mannitol and concerta at the same time?

Yes: There are no drug-drug interactions between mannitol and concerta. ...Read more

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Is it safe to use mannitol as a coffee sweetener?

Is it safe to use mannitol as a coffee sweetener?

Not available: Mannitol is typically dusted on gum or other foods. It is not typically availiabe for a coffee sweetener.

Stevia is a good coffee sweetener ANS is readily available at whole foods or other health food stores. ...Read more

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What is the definition or description of: Mannitol allergy?

What is the definition or description of: Mannitol allergy?

Pseudoallergy: Mannitol, not being a protein, is not a good candidate for an allergen. While it may mimic an anaphylactic reaction when given IV, it is not mediated by the allergy antibody known as IgE. However the treatment is the same as anaphylaxis. ...Read more

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Do all strains of staphylococcus ferment mannitol?

Yes: Generally, all members of the genus staphylococcus will ferment mannitol. ...Read more

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How could you tell if a bacterium fermented either: mannitol, sorbitol, adonitol or arabinose?

How could you tell if a bacterium fermented either: mannitol, sorbitol, adonitol or arabinose?

Need special tests: This is a rather sophisticated question. One that I can only answer in a very simplistic way. Basically, mannitol, sorbitol, adonitol, and arabinose are sugar alcohols. Not all bacteria can process these reduced sugars. The only way to tell is to have special media, each containing only one sugar alcohol with an indicator. Hen the media would be inoculated individually with the bacterium. ...Read more

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Can streptococcus epidermis be + or - in msa or mannitol fermentation result? Any answers appreciated!

Can streptococcus epidermis be + or - in msa or mannitol fermentation result? Any answers appreciated!

Strep and staph: Are different microbes. The Strep Epi is ubiquitous and often a contaminant of cultures. No sure I understand the mannitol part of the question. Hope this helps. ...Read more

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Is the lactulose-mannitol test very accurate in the diagnosis of intestinal permeability?

Is the lactulose-mannitol test very accurate in the diagnosis of intestinal permeability?

Should be: There is somewhat limited literature, but it seems to be a reasonable test. However, "very accurate" is subjective; it appears to have about 90% sensitivity, only about 50% specificity though. ...Read more

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How long can cerebral edema take to be cured. Doctors aren't giving mannitol. But there is improvement in friends health. 60% conscious now.

How long can cerebral edema take to be cured. Doctors aren't giving mannitol. But there is improvement in friends health. 60% conscious now.

Each case different: It depends how severe is the brain edema and what the cause is. Mannitol is temporary treatment and only a protective measure. It usually resolves after a few days while the medical team tries to minimize damage with the different treatment modalities. Being conscious is the best sign of improvement. ...Read more

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Why is a person with increased intracranial pressure given the diuretic mannitol?

Why is a person with increased intracranial pressure given the diuretic mannitol?

Mannitol: Mannitol works to reduce intracranial pressure through its diuretic properties. It is usually used in the acute setting (after head trauma). ...Read more

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What are the problems with aspartame, sorbitol and mannitol that people talk about?

What are the problems with aspartame, sorbitol and mannitol that people talk about?

Loose stool, etc: All artificial sweeteners do not cause cavities but the liquid or food that you consume may contain other compounds that could be bad for your teeth, such as acid. Some research also indicates that if you consume large quantities of any artificial sweetener it may be hazardous to your health. Another side effect is if you consume large quantities of an artifcial sweetener, you can get diarrhea. ...Read more

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My bro suffer frm factor 13 def in blood, he got acute sub dural hemorrhage- 7.1*2.3cm nw, thy r givng mannitol nw. Will he be alright.?

SDH: Sorry to hear about your brother. Sdh in the setting of factor 13 def is worrisome. Your brother's doctor would be the best person to answer your question as they have the clinical and imaging information. ...Read more

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Dysnea + cough, negative mannitol test, high nitric oxide, normal FCV & FEV1, very low MEF 25, low DLCO, high PEmax & very low PImax. What disease?

Dysnea + cough, negative mannitol test, high nitric oxide, normal FCV & FEV1, very low MEF 25, low DLCO, high PEmax & very low PImax. What disease?

See pulmonologist: If the corrected DLCO is low, I would suspect interstitial lng disease. However it is difficult to make a diagnosis based on test results alone and I would thus recommend that you consult a pulmonologist. If your FeNO is only slightly elevated (35 ppb range), it may mean nothing. But if highly elevated, then an eosinophilic inflammation should be considered. ...Read more

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Can mannitol be used to reduce edema weeks after surgery, or only immediately after trauma? Patient suffers from aphasia after removal of glioblastoma

Can mannitol be used to reduce edema weeks after surgery, or only immediately after trauma? Patient suffers from aphasia after removal of glioblastoma

Mannitol: For cerebral edema is only a temporizing measure. Its affects are short lived. The mannitol can eventually cross into the region of pathology and draw water into the lesion via osmotic pressure (making the swelling worse). ...Read more

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Because of negative mannitol test & heavy dysnea, Dr. Ordered methacholine challenge, but my dna shows pseudocholinesterase deficiency. Safe test?

Because of negative mannitol test & heavy dysnea, Dr. Ordered methacholine challenge, but my dna shows pseudocholinesterase deficiency. Safe test?

Methacholine: Did you have PFTs? First do that, Rrare to use methacholine in the US as those with asthma can have a severe response. Discuss your deficiency and PFTs wtth your doctor. Methacholine is metabolized by acethycholinesterase and si resistent to inactivation by pseuodcholinesterase, so that should not be a factor.

See http://www. Rxlist. Com/provocholine-drug/clinical-pharmacology. Htm ...Read more

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Exhaled nitric oxide elevated, mannitol test negative. Nothing to see in CT. Severe dyspnea with normal lung function and cough. Any suggestion?

Exhaled nitric oxide elevated, mannitol test negative. Nothing to see in CT. Severe dyspnea with normal lung function and cough. Any suggestion?

Other causes: Exhaled nitric oxide need to be over 35 ppb to be considered abnormal. Severe dyspnea may be from a cardiac issue and if the problem occurs with breathing air in, it may be from vocal cord dysfunction. An ENT doctor may be able to confirm the diagnosis. Let me know what turns out eventually ...Read more

Dr. Oren Sagher
239 Doctors shared insights

Mannitol (Definition)

Mannitol is a nasal preparation which is a kind of ...Read more