Doctor insights on:
Mandol Second Generation Cephalosporin
Would the older or newer generation of cephalosporins antibiotics be more likely to cause anaphylaxis in patients severely allergic to penicillin?
See below: Persons with type 1 immediate hypersensity to penicillin antibiotics should generally avoid taking cephalosporin antibiotics because of the low but real risk of cross allergenicity. Safe alternative antibiotics include vancomycin, septra, (sulfamethoxazole and trimethoprim) macrolides, tetracyclines, aztreonam, clindamycin, zyvox, quinolones etc.See 2 more doctor answers
Today my doctor prescribe a infertility medicns i.E tinidazole , l_methylfolate, chymoral forte, third generation cephalosporin.Is that good medicn?
Not fertility meds: The medications you are describing are several antibiotics, vitamins and enzymes. None of these are infertility medications. If you are not sure why he/she prescribed them, you should ask your doctor what they are for.
I may need cephalosporin therapy with a suspected penicillin allergy. How does it work? Do I take a 3rd generation by mouth and sit in an ER waiting room with a buddy and an epipen (epinephrine)?
Penicillin allergy: Among all patients reporting penicillin allergy, 85 to 90% will tolerate a penicillin, either because they were never allergic or because they had an earlier allergy that subsequently resolved. Among penicillin skin test-positive patients, approximately 2% will react to a cephalosporin.See 1 more doctor answer
Pcn & Cehalosporins: The conventional number is 10% of penicillin allergic people are also allergic to cephalosporins, however the data is weak since the patient reported incidence of penicillin allergy may only be 10% accurate. There are also 3 generations of cephalosporins and the "cross reactivity" may vary between them. There does seem to be a direct relationship between reaction severity and cross reactivity.
Macrolide: No. It is a macrolide.Get a more detailed answer ›
Drug Allergy: Your body needs to be exposed to the allergen first. If you are allergic, second and subsequent exposure will cause allertic reaction.
Yes: Totally unrelated molecules so it's ok.Get a more detailed answer ›
Yes: These meds are totall different and there is no cross sensitivity.
Depends: Relatively few people have reactions...In the 10 % range by some accounts. There are always alternatives. The real question should be what kind of penicillin allergy is being reported.
Autoimmune reaction: Cephalosporins interact with red blood cell membranes. The body can sometimes produce antibodies against cephalosporins that also interact with the surface of red blood cells. These antibodies thus activate the body's immune system to attack its own red blood cells, causing hemolytic anemia. This is a rare but severe side effect of cephalosporins.
Is mrsa, mssa , staph a ß-lactamase producing strains , susceptible to third , fourth, and fifth cephalosporins?
Complex: Cannot answer this simply. Mssa should be sensitive to all cephalosporins. Mrsa will be resistant to all. Have no idea what else you are asking.
Yes: Allergy to the entire class of antibiotics called cephalosporins is indeed possible. That allergy would be the common part of the molecule shared by all cephalosporins and penicillins, the beta-lactam ring.
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