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Doctor insights on: Malignant Neoplasm Of Bone Marrow

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Is leukopenia the symptom of bone marrow cancers like leukemia?

Is leukopenia the symptom of bone marrow cancers like leukemia?

Sometimes: Leukopenia (low white blood cell count) can be a symptom of bone marrow cancers like leukemia or myelodysplasia. There are many other less serious reasons to have low white blood cells too. ...Read more

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Dr. Barry Rosen
4,458 doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


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How are bone cancer and cancer of the bone marrow different?

Dr. M. Jan Dr. Jan
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How are bone cancer and cancer of the bone marrow different?

Big difference: Bone cancer is the cancer of bony part of the bone and cancer of the bone marrow is the cancer of blood. ...Read more

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Will a bone marrow transplant cure bone marrow cancer?

Will a bone marrow transplant cure bone marrow cancer?

Yes: However it depends on the type of cancer, if it is in remission or not ,age of the patient and the type of donor. It also depends on the type of transplant, from self or another donor ...Read more

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Mesothelioma biopsy says 'portions of fibrous tissue infiltrated by malignant cells forming nests. tumor cells +'ve for CK7 and calretinin. prognosis?

Mesothelioma biopsy says 'portions of fibrous tissue infiltrated by malignant cells forming nests. tumor cells +'ve for CK7 and calretinin. prognosis?

Marker not prognosis: CK7 and calretinin are used to verify that the tumor is mesothelial in origin (versus adenocarcinoma of the lung). It does not provide information about prognosis. Factors associated with pleural mesothelioma prognosis include: functional status, blood counts, histology (epithelial best vs fibrosarcomatous poorest), and tumor size (degree of involvement of pleural cavity). Several new trials. ...Read more

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Describe the features of bone marrow disease.?

Describe the features of bone marrow disease.?

More detail needed: Bone marrow diseases are many and diverse. Can you be more specific in your question? ...Read more

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4%plasma cells in bone marrow biopsy-how serious is it?

4%plasma cells in bone marrow biopsy-how serious is it?

Can be normal.: Up to 5% is normal as long as they are not "monoclonal" meaning derived from a cell. If monoclonal then a bone cancer called myeloma needs to be ruled out. If no bone disease, anemia, high calcium or kidney disease answer is MGUS, a pre-cancerous condition with low risk of progression (less than 1% per year). ...Read more

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Can malignant mesothelioma cause a bone tumor?

Can malignant mesothelioma cause a bone tumor?

Direct invasion: Or blood borne metastasis from a pleural, chest wall tumor to an adjacent rib or distant site. We'd call this bony metastasis, a bone tumor infers that it started out in a bone, not innocently affected from another king of cancerinvading it. ...Read more

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What distinguishes cancer cells from the cells of benign neoplasms?

What distinguishes cancer cells from the cells of benign neoplasms?

Disordered growth: Benign tumors grow locally and do not spread. Under the microscope, the cells look like the gland they are from and they are not invading. Cancer cells have disordered growth, frequently do not look like the originating gland and show invasion. ...Read more

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What is the hypercellular bone marrow?

What is the hypercellular bone marrow?

The bone marrow: Changes as we age. The cellularity is the percentage of blood cell production as compared to fat. As a rule of thumb the cellularity as a percent is 100 - your age. Hypercellularity means that number is higher than expected. ...Read more

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Which distinguishes cancer cells from the cells of benign neoplasms?

Which distinguishes cancer cells from the cells of benign neoplasms?

Genome destabilized: The key to cancer is that enough mutations have accumulated to render the genome itself unstable. Eventually a clone will acquire the ability to invade and spread. We can pick this up using molecular biology techniques. They also look different, but it takes a pathologist several years to learn to tell all the subtleties. ...Read more

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How dangerous is a bone marrow cancer myeloma?

How dangerous is a bone marrow cancer myeloma?

Very: Multiple myeloma a plasma cell cancer could be very dangerous in some , in others ( the lucky ones ) the diseases can run for years. Have to speak to the treating oncologist good prognostic signs are higher albumin, lower beta 2 microglobulins, , plasma cell dna showing not having high risk chromosomal abnormalities. ...Read more

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What causes bone marrow tumors to form?

Do not know: There are multiple different types of bone marrow tumors and the cause for almost all is unknown. A few things like exposure to benzene and radiation do predispose a person to leukemia. You may consult this site for info: http://www.mayoclinic.org/diseases-conditions/leukemia/basics/causes/CON-20024914 For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Drink enough water daily, so that your urine is mostly colorless. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form. Practice safe sex, if you have sex. ...Read more

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Is lymphoma a type of bone cancer?

Is lymphoma a type of bone cancer?

Not technically : Lymphoma is a cancer derived from lymphocytes (immune cells) that are broad classified as B or T lymphocytes. They are normally present in the bone marrow so lymphomas commonly involve this area, but they are not derived from "bone" as most people think of bone. ...Read more

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Does the presence of bright cd8 t-cells on bone marrow biopsy indicate cancer?

Does the presence of bright cd8 t-cells on bone marrow biopsy indicate cancer?

Not really: Presence of cancer cells is only indication of cancer no other cells., to call it a cancer you have to see cancer cells nothing else . Cd-8 t cells are seen in viral infections also . These cells are some times seen surrounding the tumor or inside the tumor which is a good prognostic sign presence of immunity , body is fighting the cancer. ...Read more

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Define differential diagnosis of prolymphocytic leukemia or mantle cell leukemia.

Define differential diagnosis of prolymphocytic leukemia or mantle cell leukemia.

They are too differe: There should be no confusion between these two entities. One is a lymphoma(nodal disease) the other one is a blood cancer that should not affect the lymph nodes. Rather easy diagnosis if you are seeing the right type of specialist! ...Read more

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How can you differentiate primary malignant bone tumor from metastatic bone disease in x-ray?

How can you differentiate primary malignant bone tumor from metastatic bone disease in x-ray?

Several ways: A primary bone tumor might have certain radiographic characterisitics that are different than metastatic bone disease. Multiple bone tumors strongly suggests metastases. The presence of a prior cancer also strongly suggests that a bone tumor is metastastic. ...Read more

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Is fibrosarcoma a type of bone cancer?

Is fibrosarcoma a type of bone cancer?

It depends: Fibrosarcoma is a type of cancer. That diagnosis is given based on how it looks under the microscope when the pathologist examines it. It can occur either in bone or in soft tissues, so it can be a bone cancer. If it occurs in bone, the treatment is chemotherapy and surgical removal of the tumor. If it occurs in the soft tissues, then surgical removal is done, but chemotherapy is controversial. ...Read more

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Do bone marrow aspirations mean leukemia?

Do bone marrow aspirations  mean leukemia?

No: We do them for several reasons including evaluation for an abnormal cbc. Sometimes we are concerned about leukemia but the other reasons include the following: anemia, low platelets, staging of lymphoma, monitoring therapy. Hope this helps. ...Read more

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Low bone marrow is it a cancer?

Low bone marrow: Not sure what you mean by low bone marrow. Was a bone marrow biopsy performed that shows less than the normal number of cells? Why was the bone marrow looked at in the first place? Please ask the question again with more details. ...Read more

Bone Marrow (Definition)

Bone marrow is the flexible tissue found in the interior of bones. In humans, red blood cells are produced in the heads of long bones, in a process known as hematopoesis. On average, bone marrow constitutes 4% of the total body mass of humans; in an adult weighing 65 kilograms (140 lb), bone marrow accounts for approximately ...Read more


Neoplasms (Definition)

"tumor" literally translates as "mass", so even a fresh bruise could be called a "tumor". Doctors use the term "neoplasm" (tranlates literally as new growth) to describe tumors that are abnormal growths of cells. These may be benign or malignant; "malignant" = cancer. In everyday usage, we use "tumor" ...Read more