Top
20
Doctor insights on: Malignant Melanoma Treatment Guidelines

Share
1

1
What are the treatment options for malignant melanoma cancer?

What are the treatment options for malignant melanoma cancer?

Many: The treatment for melanoma involves removing the primary site with a margin depending on the depth of the melanoma. In addition for high risk lesion a sentinel lymph node biopsy is performed. If these lymph node contains melanoma the remainder of the lymph nodes are removed from that basin. Treatment for distant disease can involve surgery, chemotherapy and or immunotherapy. ...Read more

See 1 more doctor answer
Dr. Sewa Legha
131 doctors shared insights

Malignant Melanoma (Definition)

Malignant melanoma is a cancer that begins usually in the pigmented cells (melanocytes) of the skin. It is generally considered the most dangerous form of skin cancer. Most cases are localized and caught fairly early but some people will develop widespread ...Read more


2

2
Pathology moderate atypical dysplastic nevus, recommend further excision. Is this cancer/melanoma?

Pathology moderate atypical dysplastic nevus, recommend further excision. Is this cancer/melanoma?

Not yet: It may develop into a malignancy but is not yet. The borders may be incompletely excused, or te pathologist may feel that a wide enough clear margin has not been achieved. ...Read more

See 4 more doctor answers
3

3
Is malignant melanoma totally curable?

Is malignant melanoma totally curable?

No: It depends on the stage. Stage ia has about a 98% cure rate, but most people with stage 4 will not be cured with any of the treatments that we have available. ...Read more

See 2 more doctor answers
Dr. Liawaty Ho Dr. Ho
4 doctors agreed:
4

4
What procedures treat nonmelanoma skin cancer?

Dr. Liawaty Ho Dr. Ho
4 doctors agreed:
What procedures treat nonmelanoma skin cancer?

Depends: Depend on what type of cancer? Squamous cell, basal cell, skin lymphoma? Etc. Surgical resection if localized on the skin and if indicated. If it is already spreading to distant organ-then systemic therapy ( chemo or other biological agent) will be the option. In certain cancer on the skin -radiation therapy, uv therapy , topical chemotherapy , interferon etc-could be the treatment as well. ...Read more

See 1 more doctor answer
5

5
Is surgery ever appropriate for metastatic cancer?

Is surgery ever appropriate for metastatic cancer?

Yes: Yes. In general surgery is not useful for metastatic (spread) cancer. However in oligo (few) metastatic cancer -- especially for breast, colon, melanoma cancers patients may be rendered stage 4 ned (no evidence of disease). This may improve local control and symptoms, survival, and in a few cases even lead to cure. Removing the primary tumor (kidney) in renal cell carcinoma is helpful in met rcc. ...Read more

See 1 more doctor answer
6

6
Is metastatic melanoma preventable?

Is metastatic melanoma preventable?

Yes and No: Certain genetic conditions may predispose someone to malignant melanoma. But there are certainly things that can be done to boost one's immune system to fight cancers. And those with irregular moles should be seen at least yearly by their doctor or dermatologist to remove suspicious moles. Therefore, preventing a metastatic process. ...Read more

See 2 more doctor answers
7

7
Please describe treatment options for metastatic melanoma?

SOC vs. trial: I agree with dr. Ho about standard of care (soc) options vs. Clinical trial. One online way to evaluate clinical trials based on tumor biomarkers in melanoma is here: http://www.Collabrx.Com/melanoma. ...Read more

See 2 more doctor answers
8

8
What are the criteria for determining malignancy in melanoma? Aren't all melanoma malignant?

What are the criteria for determining malignancy in melanoma?  Aren't all melanoma malignant?

Yes: All melanomas are considered malignant however they have different levels of metastatic potential. This means that some melanomas have the ability to spread to other parts of the body while others, especially in situ melanomas, have little or no risk of metastasis. ...Read more

See 1 more doctor answer
9

9
Is renal cell carcinoma stage 4 an aggressive cancer?

Is renal cell carcinoma stage 4 an aggressive cancer?

Stage 4 : Stage 4 renal cell carcinoma usually means that the cancer has spread to other parts of the body. At this stage, the cancer is consider very aggressive. www.peedoc.com @drhtay. ...Read more

10

10
Need expert opinions about skin cancer radiation treatment?

Need expert opinions about skin cancer radiation treatment?

Not usual Rx: Radiation is not usually used to treat skin cancer. Surgery is the usual approach. See this site for more info. http://www.mayoclinic.com/health/skin-cancer/ds00190. ...Read more

12

12
Is melanoma cancer curable/reversible?

Is melanoma cancer curable/reversible?

Very curable: In its early stages. Once it has spread from the primary site to other organs, the prognosis is much worse. Early treatment is key to a good outcome. ...Read more

14

14
How high is survival rate for malignant melanoma?

Varies: It depends on depth of melanoma at time of excision and whether any lymph nodes are involved. Early melanomas less than .75 millimeters have close to a 100 per cent survival. Dpeer melanomas greater than 1 mom, then greater 2 mm, and 3 mm. Have lower per cent age of 5 year cure rate. There are 2 new drugs for advanced melanomas. Early treatment is essential. ...Read more

See 1 more doctor answer
15

15
Why does basal cell carcinoma have better prognosis than malignant melanoma?

Why does basal cell carcinoma have better prognosis than malignant melanoma?

Ability to travel: Basal cell carcinoma usually is limited to the site of disease. While it is possible for basal cell to metastasize it is very rare. In contrast melanoma travels through the lymphatic system and can form tumors in any location of the body. ...Read more

See 2 more doctor answers
16

16
How effective is fluorouracil (Efudex) for treating basal cell cancer?

How effective is fluorouracil (Efudex) for treating basal cell cancer?

Very: The majority of small and even intermediate basal cell cancers can be cured by applying EFUDEX (fluorouracil). The resulting erythema is secondary to destruction of local suppressor cells in the tumor field and influx of effector cells to destroy the tumor. The EFUDEX (fluorouracil) is applied locally for 10 days followed by 10 days of A&D ointment May repeat if needed. ...Read more

17

17
Good diagnosis technique papillary cancer? Http://thyroid.About.Com/od/cancergoiternodules/a/veracyte-afirma-thyroid-analysis-nodules.Htm"

Good diagnosis technique papillary cancer? 
Http://thyroid.About.Com/od/cancergoiternodules/a/veracyte-afirma-thyroid-analysis-nodules.Htm"

Start w/the basics: A better question is: how do you diagnose a thyroid mass? Since 99% of thyroid masses are benign, you wouldn't start out by looking for one type of tumor. Feel the neck and observe for multiple lumps. Go to an ultrasound to check out the fluicd content (suggesting cysts). If it appears to be a solid mass, go for either a nuclear scan or a needle biopsy. Open biopsy or surgery comes last. ...Read more

See 2 more doctor answers
18

18
Stage 2B IDC breast cancer, her2+/ER/PR+Neoadjuvant taxol, (paclitaxel)A/C,lumpectomy,rads, lymphovascular invasion. What does this mean for prognosis & follow up?

Stage 2B IDC breast cancer, her2+/ER/PR+Neoadjuvant taxol, (paclitaxel)A/C,lumpectomy,rads, lymphovascular invasion. What does this mean for prognosis & follow up?

Prognosis fair: Stage IIb breast cancer is usually palpable at 2-5 cm. and at time of procedure to remove lesion, sentinel nodes are + suggesting axillary dissection and reason for neoadjuvant therapy. Lymphovascular invasion increases chance for recurrence. With Her2+ Herceptin (trastuzumab) with chemo should be used and PET/CAT needed to assure met foci not missed in distal organs. Carful follow up needed. ...Read more

19

19
What is the survival rate for malignant melanoma?

Depends on stage: 5 year overall survival: stage i: 85-95% stage ii: 53-80% stage iii: 40-80% stage iv: 15-20%. ...Read more

See 3 more doctor answers
20

20
Stage iii-b colon cancer removed surgically. Suspected liver lesion resected and analyzed with not malignancy. Is kras analysis needed for recurrence?

Stage iii-b colon cancer removed surgically. Suspected liver lesion resected and analyzed with not malignancy. Is kras analysis needed for recurrence?

Possibly: For initial treatment after surgery, you shouldn't need to get kras testing. However, if this is metastatic or recurrent colon cancer, then it may help to determine if egfr based therapies like Cetuximab can help (they only work for kras "wild type"). Remember that if you do recur (god forbid), management may be different at that future time! not something to worry about with your current story. ...Read more

See 1 more doctor answer
Dr. Mike Bowman
962 doctors shared insights

Skin Cancer (Definition)

A condition in which some element of your skin which is one of the most complex organs in the body, degenerates into cancer, with the cancerous (malignant) cells growing ...Read more


Malignant (Definition)

The term “malignant” is mainly used in the context of cancer, but can also be used to describe a condition that can be acutely damaging to the body, ...Read more