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Doctor insights on: Malignant Melanoma And Enbrel

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Is it safe for a pt with history of basal cell carcinoma and squamous cell carcinoma (father died of malignant melanoma and sister has had a melanoma removed) to take enbrel (etanercept) for ra? Red hair, blue eyes.

Is it safe for a pt with history of basal cell carcinoma and squamous cell carcinoma (father died of malignant melanoma and sister has had a melanoma removed) to take enbrel (etanercept) for ra? Red hair, blue eyes.

Immunosuppressant: Enbrel (etanercept) is an immunosupressant to minimize yuur bodies attack of itself. Anything that lowers your immune system may increase your risk for certain cancers such as lymphoma, basal and squamous cell cancers, particularly if you are already fair skinned. Good sun block, wide brimmed hats, minimize sun exposure, etc. Your doctor should be able to discuss the relative risks of treatment of enbrel (etanercept). ...Read more

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Dr. Mike Bowman
906 doctors shared insights

Skin Cancer (Definition)

Skin is the largest and one of the most complex organs in the body composed of hundreds of different structures. Nearly any of these elements can degenerate into cancer. However the three most common are: basal cell, squamous cell and melanoma which occur in that order and degree of aggressiveness. Although heredity plays a major role, sun exposure and tobacco use & ...Read more


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What is a malignant melanoma?

What is a malignant melanoma?

Skin cancer: In its most typical form, melanoma is a cancer that originates in cells of the skin called melanocytes. In some cases melanoma can spread to other organs from the skin. More rare types of melanoma start in the eyes, colon, mouth, bladder and other organs. ...Read more

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What are the symptoms of malignant melanoma?

What are the symptoms of malignant melanoma?

Varies: Many melanomas are without symptoms. Some are itchy, irritated, or may bleed. They have often changed shape, size or color, but these changes are usually asymptomatic. If the melanoma has spread, there are multiple other symptoms that could possibly occur. ...Read more

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Is malignant melanoma totally curable?

No: It depends on the stage. Stage ia has about a 98% cure rate, but most people with stage 4 will not be cured with any of the treatments that we have available. ...Read more

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Safe to get pregnant with history of malignant melanoma?

Safe to get pregnant with history of malignant melanoma?

Controversial: A very good question, and the answer is not clear. Some experts believe that pregnancy increases the risk of melanoma and advise women with a melanoma history to avoid pregnancy, or at least wait several years. Others say the evidence to support that recommendation is not convincing. Until we have a definite answer i would be very cautious; if you get pregnant, have your skin examined frequently. ...Read more

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What is the best treatment for typical malignant melanoma?

What is the best treatment for typical malignant melanoma?

Usually surgery: Assuming that the melanoma has not spread to other organs, the first treatment is to surgically remove the affected skin with a rim of normal skin. Then, certain patients will also need to have an operation to remove 1 or more lymph nodes depending on the spread. In select cases, melanoma that has spread to other organs is surgically removed. Other patients will need chemotherapy and radiation. ...Read more

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Could liver nodules be a recurrence of past malignant melanoma?

Could liver nodules be a recurrence of past malignant melanoma?

Possible: Nodules in the liver can be caused by many different things. A patient with a history of melanoma and the development of new liver lesions would warrant further investigation. ...Read more

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Help please? What is the difference in malignant melanoma and metastatic melanoma?

Melanoma: Malignant means cancerous. It's redundant to say malignant melanoma, as all melanoma is cancerous (although the term is still used). Metastatic means that it has spread to lymph nodes or other organs of the body. ...Read more

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I have malignant melanoma in radial stage with minimal microscopic invasion. Could this have spread already, I am waiting for wide excision .

Information: Radial grownth phase is probably better than vertical. Melanomas less that 1mm thick have excellent prognosis. The pronosis depends primarily on thickness. Other factors include ulceration, lymphocytic response, regression, tumors in the 1-4mm range benefit from sentinal node biopsy. ...Read more

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Malignant (Definition)

The term malignant can be used in several medical contexts, but is primarily used to describe cancers. More dangerous and disorderly than the benign growth of cells, malignant cells have developed genetic changes that can allow it to invade other tissues in an unregulated way. These tumors can later spread, or metastasize, to other parts of the body and ...Read more


Dr. Sewa Legha
112 doctors shared insights

Malignant Melanoma (Definition)

Malignant melanoma is a cancer that begins usually in the pigmented cells (melanocytes) of the skin. It is generally considered the most dangerous form of skin cancer. Most cases are localized and caught fairly early but some people will develop widespread ...Read more