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Doctor insights on: Major Depression Melancholia

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What is the difference between major depression with melancholia and major depression?

A subtype: Melancholia is a subtype of depresson which generally is more severe with lack of reactivity in mood. There are more physical symptoms of no drive, motivation, apathy but can have a dramatic change from am to pm with much worse mood in the am. Melancolic depression is less responsive to therapy alone and often requires multiple medications or ect. ...Read more

Dr. Heidi Fowler
462 doctors shared insights

Major Depression (Definition)

Major depression is a mood disorder where a person is persistently sad or depressed for at least two weeks with changes in sleep, appetite and weight. Change in mood could also present as irritability. Low energy or persistent lethargy is also seen. Hopelessness and disinterest in enjoyable activities is common. Suicidal ideation is a sign of worsening depression ...Read more


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Is there a difference between major depression w/ melancholia and severe major depression?

Is there a difference between major depression w/ melancholia and severe major depression?

Depression: Melancholia can be a feature of severe depression. Not all severe depressive disorders have this as the main symptom. Although there is a relationship with severity. ...Read more

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I have major depression an anxiety.. I've tried many dif pills.. Y am i still so depressed an what should I do? I am 27 yrs old. I was diagnosed with major depression an anxiety in 2007.. Till this day it has gotten worse.. In the past 2 yrs I have been h

I have major depression an anxiety.. I've tried many dif pills.. Y am i still so depressed an what should I do? I am 27 yrs old. I was diagnosed with major depression an anxiety in 2007.. Till this day it has gotten worse.. In the past 2 yrs I have been h

Get a second opinion: This sounds like a situation where a second opinion is warranted and if you have not been in therapy you should be. A review of all your lab work and another physical should also be done. If you are sleepy, sleep apnea should be ruled out. ...Read more

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Can general anesthia affect a person with major depression? Make them feel more depressed.

Can general anesthia affect a person with  major depression?  Make them feel more depressed.

Yes possible: Genera anesthesa can leave you feeling weak and somnolent. This may make you temp. Depressed. Also hospital stays along with bed rest may increanse depression. Once anesthesia clears your system, you should feel less depressed. Why not discuss this with your dr. ...Read more

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Is evidence of elevated mao enzymes in the brains of clinically depressed people a biological marker of major depression?

Depression: No tests to diagnose depression. It is a clinical diagnosis means by seeing the patient asking question and mental status exam done by a doc. ...Read more

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How do I treat major depression without medications?

How do I treat major depression without medications?

Therapy: Can be effective, but the time required would be much greater than therapy plus medications. Why not get the best treatment available? ...Read more

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How can major depression affect my work?

See Below: Difficulty concentrating, keeping focus, low or lack of motivation, irritability, depending on severity, some people might start skipping showers, or taking care of their basic needs, which inadvertently will affect your work and out-of work relationships. Some people get more angry, having "shorter fuse". If you feel you're being affected, get evaluated and start treatment (meds and psychth). ...Read more

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What's the difference between minor depression or major depression?

A milder form of MDD: Minor depression is a mood disorder that does not meet full criteria for major depressive disorder but in which at least 2 depressive symptoms are present for 2 weeks or more. It is usually quite responsive to psychotherapy interventions. In the diagnostic & statistical manual of mental disorders iv, minor depressive disorder was cited as an example of depressive disorder not otherwise specific. ...Read more

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Why can't my major depression go away?

Why can't my major depression go away?

Depression is: Treatable. I know that you are on Effexor - but don't know what other treatment you have received. Talking therapy (such as cognitive behavioral therapy or insight oriented psychotherapy) is extremely important for lasting change. Don't isolate. Spend time w people. Having a support system is very important. Get out. Don’t allow yourself to stagnate at home. Work to get at least 8 hours of sleep >. ...Read more

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I'm 42. I lived in dallas, tx until I was 40 when we moved to oahu. My major depression has kicked into overdrive. Please help ! i'm scared of life.?

Treatment can help: It is not uncommon for depression to get worse when major life changes occur (like moving from tx to hawaii).Consider calling mental health of america hawai'i m-f, 9am-4pm to describe your situation so they can help you find help(808-521-1546) hawai'i has a 24/7 help line that is staffed by caring & knowledgeable folks(808-832-3100).If you are in a really dark & dangerous place please call 911. ...Read more

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Dr. Pamela Pappas
4,419 doctors shared insights

Depression (Definition)

Include being down or sad most of the time, loss of interest/pleasure in usual activities, unintended increase or decrease in appetite/weight, sleeping more or less than usual, being agitated or lethargic, feeling worthless or inappropriately guilty or self critical, having difficulty concentrating or making decisions, & thinking of death & dying. Suicidal ...Read more


Dr. Caroline Cribari
550 doctors shared insights

Melancholia (Definition)

Melancholia is also known as depression. This is an old term for depression or dysthymia (mildly low mood), from the belief that it was caused by excess ...Read more