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Doctor insights on: Lysodren

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Dr. Abraham Jaskiel
7 doctors shared insights

Lysodren (Overview)

Lysodren is a cancer agent.


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Does lysodren cause addison's disease?

Does lysodren cause addison's disease?

Yes it can cause: Lysodren is used in dogs for treatment of Cushing's Syndrome and in humans for cancer of Adrenal and if used without these indications may cause Addisons Disease in Humans and dogs ...Read more

Dr. Abraham Jaskiel
7 doctors shared insights

Lysodren (Overview)

Lysodren is a cancer agent.


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Has anyone investigated the use of mitotane to treat GAD or other anxiety disorders?

Has anyone investigated the use of mitotane to treat GAD or other anxiety disorders?

No,not yet.: Mitotane or Lysodren is an adrenal cytotoxic agent whose exact mechanism of action is unknown. It works by slowing adrenal gland function and I can see why it may eventually be used to treat GAD. The severe side-effectys especially allergic reactions to it may limit its use. ...Read more

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Can autoantibodies against glutamine synthetase and/or glutamate dehydrogenase cause glutamate metabolism disorders?

Can autoantibodies against glutamine synthetase and/or glutamate dehydrogenase cause glutamate metabolism disorders?

Still searching: Glutamine synthase is part of the glutamine synthetase family. Ammonia incorporation in animals occurs through the actions of glutamate dehydrogenase and glutamine synthase. Glutamate plays the central role in mammalian nitrogen flow, serving as both a nitrogen donor and nitrogen acceptor. I am unble to find references in my search so far as to autoantibodies to these but see comment. ...Read more

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Can autoantibodies against glutamate receptors cause glutamate metabolism disorders?

Can autoantibodies against glutamate receptors cause glutamate metabolism disorders?

Yes. Great Question!: The Amino Acid glutamate plays a central role in nitrogen metabolism & participates in multiple biochemical pathways. Disease examples: autoantibodies to the glutamate receptor kill neurons via activation of the receptor ion channel. Anti-nmda receptor encephalitis is a treatment-responsive inflammatory encephalopathic autoimmune disease associated with anti-nmda receptor antibodies. ...Read more

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Which illness does tacrine treat?

Which illness does tacrine treat?

Tacrine: Is an Anticholinesterase & cholinergic agonist, for treatment of Alzheimer's disease. It was discontinued here about 2 years ago due to reports of liver toxicity. ...Read more

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Why were erythropoiesis-stimulating agents banned?

From sports: Because using them is cheating. Many are useful in clinical medicine. ...Read more

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Why thyrotropin used cautiously in adrenocortical insufficiency?

Why thyrotropin used cautiously in adrenocortical insufficiency?

Schmidt's: If a person is discovered to be severely hypothyroid, it is dangerous to treat it aggressively until it's been determined that adrenal insufficiency (as in schmidt's) is not also present. The jump-start that the body gets when the thyroid replacement kicks in can kill the person if there's not enough adrenal cortisol . If i've misunderstood your question, please forgive me. ...Read more

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Why are scn1a mutations commonly found in patients with alleged post-vaccination encephalopathy?

Why are scn1a mutations commonly found in patients with alleged post-vaccination encephalopathy?

Dravet Syndrome & : Related scn1a mutations are genetic, not vaccine-induced. Fever from any cause can trigger seizures. . Genetic mutations are passed on or occur by accident when the germ cells ( egg & sperm) divide & 1/2 of the germ cell's chromosomes from each parent combine for the the genetic make-up of the child. See http://www.Omim.Org/entry/182389?Search=scn1a%20expression&highlight=expression%20scn1a. ...Read more

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Is benzene epinephrine?

Is benzene epinephrine?

No: Benzene is a very toxic organic (carbon-based) chemical. Structure here: http://en.Wikipedia.Org/wiki/benzene Epinephrine is another name for adrenaline which acts as a hormone and a neurotransmitter in humans and other mammals. Structure here: http://en.Wikipedia.Org/wiki/epinephrine Epinephrine includes a "benzene" ring, but the attached groups give it its unique behavior. ...Read more

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Effects of leukemia drugs: mylotarg and cytosine arabinoside?

Effects of leukemia drugs: mylotarg and cytosine arabinoside?

Mylotarg-cytarabine: Open these links: http://www.Drugs.Com/mtm/mylotarg.Html http://www.Drugs.Com/mtm/cytarabine.Html.

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Is invirase (saquinavir) used to treat hiv?

Is invirase (saquinavir) used to treat hiv?

Yes: But usually in combination with other drugs. ...Read more

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Is invirase (saquinavir) only used to treat HIV disease?

Is invirase (saquinavir) only used to treat HIV disease?

Yes, but not recentl: Invirase (saquinavir) is a protease inhibitor that is designed to treat HIV in combination with other medications. It is an older drug in this class and is not used much anymore since newer drugs require less pills per day and have fewer side effects. ...Read more

Dr. Gutti Rao Dr. Rao
1 doctor agreed:
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What is cyclic adenosine monophosphate camp?

Dr. Gutti Rao Dr. Rao
1 doctor agreed:
What is cyclic adenosine monophosphate camp?

Adenosine: Adenosine works thro' Adenosine receptors a1 , causes depletion of camp, causing hyper polarization of the cell. Adenosine causes or induces atrioventricular block resulting in correcting rhythm abnormalities such as supra ventricular tachycardia. ...Read more

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Can naltrexone combat Parkinson's disease?

Can naltrexone combat Parkinson's disease?

???: Naltrexone is used for opioid dependence. I have not heard of it being used for parkinson disease. ...Read more

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What are commonly used Serotonin Antagonists used for Serotonin Syndrome?

What are commonly used Serotonin Antagonists used for Serotonin Syndrome?

Chlorpromazine: is most commonly used..HOWEVER most "serotonin syndrome: cases are CAUSED by MEDICATIONS which should be stopped!!!!! Hope this helps Good Luck Dr Z ...Read more

Dr. Costantine Albany
10 doctors shared insights

Mitotane (Definition)

Mitotane ...Read more