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Doctor insights on: Lyrica Vs Gabapentin Side Effects

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What drug has the least side effects to treat pain...Gabapentin lyrica (pregabalin) or cymbalta?

What drug has the least side effects to treat pain...Gabapentin lyrica (pregabalin) or cymbalta?

Would pich gabapenti: Any day i would pick Gabapentin over other based on clinical experience with side effects unless Gabapentin is not working well for patient. ...Read more

Gabapentin (Definition)

Also called neurontin, (gabapentin) is an anticonvulsant medication used to treat seizure, also for post-herpetic neuralgia & other neuropathic pains, as well as restless leg syndrome. It works by lowering excitation ...Read more


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I recently had a bad side effect from gabapentin. Urine retention and bladder infection. Will lyrica (pregabalin) do the same thing? Side effects?

I recently had a bad side effect from gabapentin. Urine retention and bladder infection. Will lyrica (pregabalin) do the same thing? Side effects?

Pregabalin: Pregabalin (lyrica) is prescribed for chronic pain conditions and neuropathy. Not necessarily, it will cause the same side effects than Gabapentin (neurontin) and if there are no relief with other agents, it is worthy to start a trial at low dose, and observe the response. ...Read more

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Are there any side effects switching from Neurontin to lyrica (pregabalin)?

Are there any side effects switching from Neurontin to lyrica (pregabalin)?

Not usually: If the dose is equivalent, there should be no difference in tolerability. In a few cases, edema in the lower legs may develop with Lyrica (pregabalin) even if it didn't occur with Gabapentin. Good luck ...Read more

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Just started lyrica (pregabalin) 75mg weaning off Neurontin 300mg 4 tabs a day what can I expect if any for side effects in the weaning process?

Slow taper: Taper the neurontin (gabapentin) slowly, under the guidance of your neurologist. The slower your taper, the less likely you are to experience side effects, which can include tremor, irritability, agitation, anxiety, tachycardia, diaphoresis, confusion, disorientation, catatonia, and status epilepticus. http://www.medscape.com/viewarticle/722526_1 ...Read more

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What medications to use if you've already used gabapentin and lyrica (pregabalin)?

Depend on conditions: Gabapentin and Lyrica (pregabalin) are anti-seizure medication. If you talk them for seizure, there are many more choices. If you take them for nerve pain, you might benefit from medication change. Please see your doctor to discuss your concern. ...Read more

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What is the difference between the medications Neurontin (gabapentin) and lyrica (pregabalin)?

Basically price: Gabapentin is older and available generically, so much cheaper. Lyrica (pregabalin) is newer dosages are different and somewhat less frequent than gabapentin. Lyrica (pregabalin)- because it is newer has more indications ( labelled uses- ie postherpetic neuralgia and fibromyalgia) but Gabapentin will work just as well. Gabapentin(neurontin) was originally marketed for seizure disorders but more commonly used for neuralgi. ...Read more

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Can you change from gabapentin to lyrica (pregabalin) without gradually withdrawing from gabapentin?

Overlap or not : Usually and depending on how long one has been taking a certain medication , we try to overlap one medicine is tapered down and one is tapered up. However we do stop meds and switch without taper sometimes. Your prescribing doctor is the best to judge your situation, please discuss that with him. Good luck and feel better. ...Read more

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I am currently on gabapentin 1200 mg a day and was wondering if since it's not working good should I try lyrica (pregabalin) ?

Gabapentin lyrica (pregabalin): usually if gabapentin does not appear to be working switching to lyrica (pregabalin) is reasonable. You also might want to try Horizant as the bioavailability is better. ...Read more

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To avoid back past medical bills and another bill for the dr could I get something prescribed on here? I have been on Lyrica & gabapentin

You would need to: become a patient to have medications prescribed. Have you considered Health Tap Concierge? ...Read more

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For mononeuropathy, would 900mg of gabapentin (x3 a day), or 75mg of lyrica (pregabalin) (3x a day) be better? I still hv pain w/both esp. first thing in the a.m.

For mononeuropathy, would 900mg of gabapentin (x3 a day), or 75mg of lyrica (pregabalin) (3x a day) be better? I still hv pain w/both esp. first thing in the a.m.

Impossible to say: Different people respond differently. Some will do better on gabapentin and some on Lyrica (pregabalin). Your gabapentin dose is high and your Lyrica (pregabalin) dose is relatively low so you are really comparing apples and oranges. ...Read more

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How does gabapentin help crps? Is lyrica (pregabalin) better?

How does gabapentin help crps? Is lyrica (pregabalin) better?

Possibly: Either one of these agents may provide benefit. One is not consistently better than the other. The best one is the one that works best for you. ...Read more

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It has been over11 days why am i still showing positive for benzo. I take lyrica, (pregabalin) gabapentin , hydrocone , and nexium?

It has been over11 days why am i still showing positive for benzo. I take lyrica, (pregabalin) gabapentin , hydrocone , and nexium?

Which benzo?: It depends on what you took along with the other medications you mention. Some benzodiazepines (like Klonopin (clonazepam) and valium, for instance) have very long half-lives. ...Read more

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Please describe efficacy difference in Lyrica (pregabalin) vs Gabapentin for migraine/headache of a very nervey type?

It depends: Efficacy refers to proven and clear superiority based on objective evidence. Hence, I doubt you'll find an answer for your efficacy question. Even the effectiveness question is problematic and in my clinical experience all I can say is that gabapentin is possibly preferable when nerve pain is associated with less rather than more anxiety. ...Read more

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My doctor prescribed 1200 mg of gabapentin for fibromyalgia about a year ago. In the past couple months, my pain has increased. The doc has told me if the gabapentin stops working, she'll switch me to lyrica. I worry about switching to lyrica due to the c

Gabapentin vs Lyrica (pregabalin): In 2007, pregabalin was received FDA approval for the management of fibromyalgia. Lyrica is not metabolized in the liver and is excreted through the kidney essentially unchanged and have no significant drug interactions. Following your doctor's advice about treatment is probably the best thing you can do. ...Read more

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I have sciatica and the only thing that works is Lyrica or gabapentin, can I get it prescribed on here? I owe too much money to my pcd to go back.

This submission: was on the health/ medical education portion of Healthtap. So, we can not prescribe this medication for you. HealthTap Prime & Concierge are designed for medical treatment but there is a fee. ...Read more

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Does lyrica (pregabalin) or Gabapentin helping with burning neuropathic pain?

Does lyrica (pregabalin) or Gabapentin helping with burning neuropathic pain?

Both can be helpful: Both Lyrica (pregabalin) and Gabapentin are used to treat the pain of neuropathy (burning, tingling and sharp, stabbing pain). People respond differently to different medications, so one might work better for one person than another. Some people have side effects to one or the other. If one doesn't work (at what should be an effective dose), it would be worthwhile to try the other. ...Read more

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What other drugs are available for nerve pain if Gabapentin, Lyrica (pregabalin) and Cymbalta don't work ?

Think beyond drugs: Medications are one way of controlling nerve pain. Pain is a complex holistic process. You may be able to decrease need for meds by addressing other issues. That includes nutrient status, stress or emotional trauma that may have accompanied or pre-dated the injury, and movement and use of the limb. It's a complex topic. You might look for a doc who does integrative or functional medicine. ...Read more

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Tried numerous meds for fibro like lyrica, cymbalta, gabapentin, savella (milnacipran). None work, not fibromyalgia?

Tried numerous meds for fibro like lyrica, cymbalta, gabapentin, savella (milnacipran). None work, not fibromyalgia?

Fibromyalgia: Certainly the diagnosis may not be correct. Make sure you have had a Rheumatology work -up. Also it may be that the meds are just not working on you. ...Read more

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I was prescribed Lyrica and use to be on Gabapentin because pain medicine makes me sick to my stomach. I haven't been able to go back to my normal dr?

Question?: What is your question? Why can't you get back to see your own physician? Gabapentin has been implicated in drug abuse and both medicines should improve your pain. ...Read more

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Which one is better for restless leg syndrome- lyrica (pregabalin) or Gabapentin?

Similar: I have tried both with some success. Lyrica (pregabalin) is more expensive and causes weight gain. I would start with gabapentin. Have you tried Requip or Mirapex already? ...Read more

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Are there any medicines like Lyrica, (pregabalin) Cymbalta, and Gabapentin that don't cause weight gain?

COMMENTS: Of the listed three, Cymbalta causes nausea in 40%, and is the least likely to cause weight gain. Savella (milnacipran) may be of value in pain syndromes such as fibromyalgia, and seems to also be less troublesome. A possible alternative to gabapentin could be Grailise or Horizant, and due to duration of action may be also less weight gain. The meds cause appetite change, so less caloric intake can prevent. ...Read more

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Does Requip cause weight gain? Does Gabapentin cause weight gain? Does Lyrica (pregabalin) cause weight gain? Thanks!

Does Requip cause weight gain? Does Gabapentin cause weight gain? Does Lyrica (pregabalin) cause weight gain? Thanks!

Mostly Lyrica (pregabalin): Weight gain is more common with Lyrica (pregabalin) or Pregabalin then with Requip or Neurontin. One can counter this side effect with a healthy diet and regular exercise. Discuss your treatment options with your doctor. ...Read more

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Meralgia parestetica six months, I've tried both lyrica, (pregabalin) gabapentin, would like nerve block, is this something I can book with a pain clinic directly?

Yes and: the nerve blockage may confirm the diagnosis. But, your pain doctor may have another consideration after the interview and physical examination. It is good to see your doctor without bring your diagnosis idea. ...Read more

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I'm on gabapentin due to bad nerve damage. I want try lyrica (pregabalin). Will my doctor keep me on both meds or do I have to pick one?

Have to pick one: They are both relatives of each other with similar modes of action - therefore it would not help to be on both. You may however tolerate one better than the other.
Other meds to try include Cymbalta (duloxetine) or Elavil - these could be combined with gabapentin.
Hope this helps. ...Read more

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Why do you gabapentin and lyrica (pregabalin) make my extremities and my face twitch?

Tics: Motor tics caused by anti epileptics is a side effect that mandated revisiting the therapy. See your neurologist. ...Read more

Dr. Joseph Weiner
668 doctors shared insights

Neurontin (Definition)

Neurontin is a seizure agent which is a kind of ...Read more