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Doctor insights on: Lymphoma

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Dr. Michael Thompson
1,754 Doctors shared insights

Lymphoma (Overview)

A malignancy developing in the lymphocytes of lymph glands. They present as an enlarging node that continues to grow and then progress to adjacent nodes.


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How does lymphoma lead to death?

How does lymphoma lead to death?

Uncontrolled growth: Lymphoma cells continue to divide and grow more than they die. Two things happen
1) their increasing size affects normal organ function or physically pushes on organs which impair their function or
2) they produce substances that are toxic or debilitate the patient
both these things eventually weaken the patient, prevent the production of normal blood cells and can lead poor immunity & infection. ...Read more

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Dr. Michael Thompson
1,754 Doctors shared insights

Lymphoma (Overview)

A malignancy developing in the lymphocytes of lymph glands. They present as an enlarging node that continues to grow and then progress to adjacent nodes.


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Leukemia/lymphoma symptom but normal blood tests. Can you explain?

Leukemia/lymphoma symptom but normal blood tests. Can you explain?

What symptoms?: Blood test may be normal in lymphoma. If you suspect either of thses disorders, it will require a detailed history, physical exaination and lab tests, including may be a biopsy. The issue is not suitable for this forum. ...Read more

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What diseases have early symptoms similar to lymphoma?

What diseases have early symptoms similar to lymphoma?

Differs: Different types of lymphoma have different symptoms. The more aggressive types frequently have symptoms such as fevers, night sweats, and unexplained weight loss. Tb (tuberculosis) is one infectious disease that can have similar symptoms, but frequently with cough. Other cancers also can have similar symptoms. Fevers and weight loss can also be part of an autoimmune disease such as lupus. ...Read more

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What are the signs of lymphoma?

B symptoms: Symptoms can include fever, night-sweats and weight loss for both non-hodgkin's lymphoma and hodgkin's disease. These are referred to as b symptoms and they are used in the staging of lymphoma. Thus a stage iii lymphoma with b symptoms would be given a stage iiib status. Other symptoms are related to pressure from the tumor causing pain, or fatigue. ...Read more

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Please explain: 5 CM irregular splenic lesion. Differential diagnosis lymphoma and splenic metastasis. Could this be cancer?

Please explain: 5 CM irregular splenic lesion. Differential diagnosis lymphoma and splenic metastasis. Could this be cancer?

Yes: Both are forms of cancer. It could also be a benign hemangioma, an epidermoid cyst, an infart (how's your overall vascular health?) or any of a number of other entities. What to do next will depend on your history and physical exam. You're in no immediate danger but this very much needs to be followed up. Many of the lymphomas especially are very curable with today's biotech. ...Read more

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Is a fine needle or excisional biopsy better to diagnose lymphoma?

Is a fine needle or excisional biopsy better to diagnose lymphoma?

Excisional: Excisional biopsy is more accurate for diagnosis of lymphoma, because the samples are much larger. Fine needle aspiration (fna) can make the diagnosis, and is much less invasive - however, the sample is much smaller, and can miss the involved portion of the lymph node. ...Read more

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What is hotchkins lymphoma?

What is hotchkins lymphoma?

Hodgkin's lymphoma: Hodgkin's lymphoma is a cancer of b cell lymphocytes in lymphatic organ/lymph glands. It is separated from other b cell lymphoma based on its unique clinical and pathological features. ...Read more

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How do you test for lymphoma?

Non-Hodgkin's test: Although a diagnosis of non-hodgkin's lymphoma can be suspected by certain lab results (ldh, spep, cbc, beta-2 microglobulin) or radiology tests (ct or pet scan), there is no way to diagnose it without doing a biopsy (of a lymph gland or the bone marrow or the affected organ). ...Read more

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Doc said "faintly positive" mono test because he saw I carried the antibody. 4 months ago with same symptoms 2 negative mono tests. Lymphoma?

Monotest: A monotest may be negative in the early stage of infectious mononucleosis and turn positive after a week or two. If your liver enzymes and CBC with differential cell count show no abnormalities, the mono has cleared. Lymphoma isn't often diagnosed by simple blood tests and requires a physical exam, xrays, scan and biopsies for definitive diagnosis. ...Read more

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Do you know what causes lymphoma?

Like other cancers..: lymphoma arises from an unlucky combination of genetic mutations in lymphoid cells during our lifetime. Risk factors include exposure to toxins, family history, or a severe immune suppression (e.g. HIV). Most often, the proximal cause can not be determined, and is mostly just bad luck, since our body is naturally subjected to millions of genetic mutations over our lifetime. ...Read more

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I have sore lymph nodes from mono for 4 months. Ent put a scope down my nose into my throat and said no cancer. Would that mean lymphoma is ruled out?

No: If you have had a positive mono spot test, it is possible for you to have lymphadenopathy (enlarged lymph nodes) for several months. The absence of any lesion in the back of the throat or larynx does not rule out lymphoma, but the virus that caused your enlarged lymph nodes is the most likely cause of your present problem. If the nodes do not resolve in 4 months or get larger, then a biopsy. ...Read more

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What is third space fluid? My dad was diagnosed with and has lymphoma. Is it treatable?

What is third space fluid? My dad was diagnosed with and has lymphoma. Is it treatable?

It means fluid....: ....Accumulation in a place it should not be, outside the blood and lymphatic systems. For example: fluid between the lung and the chest wall, fluid inside the abdominal cavity, or fluid within the tissues itself (swelling). Causes can be many in a patient with lymphoma, treatment and success of such treatments depend on the cause and many other factors. Best to you, guys. ...Read more

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How long can you live once you successfully treat hodgkin's lymphoma?

Normal life: Span. There are risks of recurrence, and late effects of treatment, but you can live as long as others in your family and friends. ...Read more

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Is consuming alcohol safe after being treated for hodgkin's lymphoma?

Possible: In limited amounts it is very possible. There could be other issues related to side effect that could impact on this. I would discuss with your oncologist. ...Read more

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Is matulane (procarbazine) just for treating lymphomas?

Is matulane (procarbazine) just for treating lymphomas?

Procarbazine is: The generic name, it is an old drug, it was one ofthe "p's" in the mopp regimen for hodgkin's lymphoma. The other "p" is prednisone, and now "platinum". Pcz was also used in brain tumors at one time, but rarely if ever any more. I hope this helps. ...Read more

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What is the treatment for transformed lymphoma?

Chemotherapy: You are referring to richter transformation. Typically treated with chemotherapy used for aggressive lymphoma. Depends on several factors, age, comorbidities, extent of disease. Sometimes radio pharmaceuticals are used as well, such as zevalin or bexxar (tositumomab). Hope this helps. ...Read more

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I am wondering what hodgkin's lymphoma treatments are there alternative to mainstream chemo and radiotherapy?

I am wondering what hodgkin's lymphoma treatments are there alternative to mainstream chemo and radiotherapy?

Beware: Alternative treatments for cancer are cropping up all over the place. Cancer patients (and their families) can be extremely vulnerable to being drawn in by promises of healing where the mainstream medical community has been unable to help much. Beware of people who would take advantage of this vulnerability with hefty up-front fees and promises of miracle-like cures. ...Read more

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How can one cure hodgkin's lymphoma with non-expensive medicine?

How can one cure hodgkin's lymphoma with non-expensive medicine?

Very difficult: The basic chemo drugs used to treat hodgkin lymphoma (adriamycin, bleomycin, vinblastine, dacarbazine) are old and cheap but the tests and infusion time with nurses and the md visits are expensive. On the other hand these drugs have a very high cure rate even for stage 4 patients. Using anything else would be unconscionable. ...Read more

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What causes fat lymphomas, how do you get rid of them without surgery and how to prevent getting more?

What causes fat lymphomas, how do you get rid of them without surgery and how to prevent getting more?

Lipomas?: If you are talking about lipomas, the benign fatty tumors that some people get, then we are not sure what causes them. There is no way to get rid of them without surgery and unfortunately they often come back when they are removed. We also do not know of a way to prevent you from getting more of them. ...Read more

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I am being treated for marginal zone n-h lymphoma with rituxin. After three treatments- no improvement. How long does this drug take? What to use next?

I am being treated for marginal zone n-h lymphoma with rituxin. After three treatments- no improvement. How long does this drug take? What to use next?

Usually: The anti-cd 20 antibody is used with cytotoxics. Commonly a pet-ct is done at the start to identify areas involved. If a lump is not responding, might re-biopsy and check markers and assure its nhl, and not hodgkin's. Alternate chemo and XRT are prospects for true resistance. ...Read more

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