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Lymphoma is cancer of the lymph system, which is an infection fighting collection of nodes of lymph tissue populated by white blood cells and ducts that drain excess fluid. The system also includes the spleen.
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Uncontrolled growth: Lymphoma cells continue to divide and grow more than they die. Two things happen 1) their increasing size affects normal organ function or physically pushes on organs which impair their function or 2) they produce substances that are toxic or debilitate the patient both these things eventually weaken the patient, prevent the production of normal blood cells and can lead poor immunity & infection. ...Read moreSee 1 more doctor answer
What symptoms?: Blood test may be normal in lymphoma. If you suspect either of thses disorders, it will require a detailed history, physical exaination and lab tests, including may be a biopsy. The issue is not suitable for this forum. ...Read more
Differs: Different types of lymphoma have different symptoms. The more aggressive types frequently have symptoms such as fevers, night sweats, and unexplained weight loss. Tb (tuberculosis) is one infectious disease that can have similar symptoms, but frequently with cough. Other cancers also can have similar symptoms. Fevers and weight loss can also be part of an autoimmune disease such as lupus. ...Read moreSee 1 more doctor answer
B symptoms: Symptoms can include fever, night-sweats and weight loss for both non-hodgkin's lymphoma and hodgkin's disease. These are referred to as b symptoms and they are used in the staging of lymphoma. Thus a stage iii lymphoma with b symptoms would be given a stage iiib status. Other symptoms are related to pressure from the tumor causing pain, or fatigue. ...Read moreSee 1 more doctor answer
Please explain: 5 CM irregular splenic lesion. Differential diagnosis lymphoma and splenic metastasis. Could this be cancer?
Yes: Both are forms of cancer. It could also be a benign hemangioma, an epidermoid cyst, an infart (how's your overall vascular health?) or any of a number of other entities. What to do next will depend on your history and physical exam. You're in no immediate danger but this very much needs to be followed up. Many of the lymphomas especially are very curable with today's biotech. ...Read more
Excisional biopsy: It can be quite important to see the entire node as the "architecture" is key to the diagnosis. Taking the node out is the "gold standard". ...Read moreSee 1 more doctor answer
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