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Doctor insights on: Lymphoma

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Dr. Michael Thompson
1,743 doctors shared insights

Lymphoma (Overview)

A malignancy developing in the lymphocytes of lymph glands. They present as an enlarging node that continues to grow and then progress to adjacent nodes.


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How does lymphoma lead to death?

How does lymphoma lead to death?

Uncontrolled growth: Lymphoma cells continue to divide and grow more than they die. Two things happen 1) their increasing size affects normal organ function or physically pushes on organs which impair their function or 2) they produce substances that are toxic or debilitate the patient both these things eventually weaken the patient, prevent the production of normal blood cells and can lead poor immunity & infection. ...Read more

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Dr. Michael Thompson
1,743 doctors shared insights

Lymphoma (Overview)

A malignancy developing in the lymphocytes of lymph glands. They present as an enlarging node that continues to grow and then progress to adjacent nodes.


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Leukemia/lymphoma symptom but normal blood tests. Can you explain?

Leukemia/lymphoma symptom but normal blood tests. Can you explain?

What symptoms?: Blood test may be normal in lymphoma. If you suspect either of thses disorders, it will require a detailed history, physical exaination and lab tests, including may be a biopsy. The issue is not suitable for this forum. ...Read more

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What diseases have early symptoms similar to lymphoma?

What diseases have early symptoms similar to lymphoma?

Differs: Different types of lymphoma have different symptoms. The more aggressive types frequently have symptoms such as fevers, night sweats, and unexplained weight loss. Tb (tuberculosis) is one infectious disease that can have similar symptoms, but frequently with cough. Other cancers also can have similar symptoms. Fevers and weight loss can also be part of an autoimmune disease such as lupus. ...Read more

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What are the signs of lymphoma?

B symptoms: Symptoms can include fever, night-sweats and weight loss for both non-hodgkin's lymphoma and hodgkin's disease. These are referred to as b symptoms and they are used in the staging of lymphoma. Thus a stage iii lymphoma with b symptoms would be given a stage iiib status. Other symptoms are related to pressure from the tumor causing pain, or fatigue. ...Read more

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Please explain: 5 CM irregular splenic lesion. Differential diagnosis lymphoma and splenic metastasis. Could this be cancer?

Please explain: 5 CM irregular splenic lesion. Differential diagnosis lymphoma and splenic metastasis. Could this be cancer?

Yes: Both are forms of cancer. It could also be a benign hemangioma, an epidermoid cyst, an infart (how's your overall vascular health?) or any of a number of other entities. What to do next will depend on your history and physical exam. You're in no immediate danger but this very much needs to be followed up. Many of the lymphomas especially are very curable with today's biotech. ...Read more

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Is a fine needle or excisional biopsy better to diagnose lymphoma?

Is a fine needle or excisional biopsy better to diagnose lymphoma?

Excisional: Excisional biopsy is more accurate for diagnosis of lymphoma, because the samples are much larger. Fine needle aspiration (fna) can make the diagnosis, and is much less invasive - however, the sample is much smaller, and can miss the involved portion of the lymph node. ...Read more

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What is hotchkins lymphoma ?

What is hotchkins lymphoma
?

Hodgkin's lymphoma: Hodgkin's lymphoma is a cancer of b cell lymphocytes in lymphatic organ/lymph glands. It is separated from other b cell lymphoma based on its unique clinical and pathological features. ...Read more

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How do you test for lymphoma ?

Non-Hodgkin's test: Although a diagnosis of non-hodgkin's lymphoma can be suspected by certain lab results (ldh, spep, cbc, beta-2 microglobulin) or radiology tests (ct or pet scan), there is no way to diagnose it without doing a biopsy (of a lymph gland or the bone marrow or the affected organ). ...Read more

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Doc said "faintly positive" mono test because he saw i carried the antibody. 4 months ago with same symptoms 2 negative mono tests. Lymphoma?

Monotest: A monotest may be negative in the early stage of infectious mononucleosis and turn positive after a week or two. If your liver enzymes and CBC with differential cell count show no abnormalities, the mono has cleared. Lymphoma isn't often diagnosed by simple blood tests and requires a physical exam, xrays , scan and biopsies for definitive diagnosis. ...Read more

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Do you know what causes lymphoma?

Like other cancers..: lymphoma arises from an unlucky combination of genetic mutations in lymphoid cells during our lifetime. Risk factors include exposure to toxins, family history, or a severe immune suppression (e.g. HIV). Most often, the proximal cause can not be determined, and is mostly just bad luck, since our body is naturally subjected to millions of genetic mutations over our lifetime. ...Read more

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