Doctor insights on:
Lympho Proliferative Disorder
Pathologic diagnosis....Resected thymus shows reactive b cell hyperplasia vs low grade b cell lympho proliferative disorder. Is this lymphoma?
Could be...: Certain lymphomas grow so slow that sometimes it is difficult for the pathologist to make the call between malignant or not. I suspect they may do additional work on the specimen and that your doctor will evaluate you further with labs, additional scans or another biopsy. If you have not seen a hematologist, maybe this is the time. Don't panic, just follow up his/her lead. Best to you. ...Read more
Tumor from Infection: Immunosuppression lowers your immune defenses. One specific infection - the epstein barr virus can be a problem because it can stimulate 1 type of white blood cells, the b lymphocytes to grow uncontrollably. If this happens, treatment may include lowering (or stopping) immunosuppression, anti-viral medication and even chemotherapy. ...Read moreSee 2 more doctor answers
Thymectomy done, thymus shows reactive b cell hyperplasia vs low grade bcell lympho proliferative disorder. What can it be? Is this serious? Treat?
What does this mean? ENDOMETRIUM, BIOPSY:
Disordered proliferative endometrium with associated simple (cystic) hyperplasia.
Endocervix exhibiting papillary hyperplasia with severe lymphoplasmatic infiltrate in the stroma.No transformation zone.what does this mean.
Pathology report: You have to go over the details with your doc. The most important word was the last word that you typed which said that the lesion was BENIGN. Not malignant. That is the key but go over it with your doc. ...Read more
Please interpret pericardium tissue
mononuclear infiltrates with rare polymorphnuclear leukocytes & eosinophiles. Hemosiderin-laden macrophages.
Not tumor: This is the site of an old bleed and probably infection or physical injury. The key is that there's not tumor found. Any interpretation beyond this without a history would be meaningless. ...Read more
Adult male,bone marrow biopsy show Erythroid hyperplasia
RBC borderline on high side,thrombocytopenia fluctuate,
Splenomegaly,negative for infections.
CBC Results: If you can send us the complete blood count (CBC) report which includes Hb, WBC, Platelet counts done from 2 different dates, we can tell you if there is anything serious or how to manage your concerns. WE need to know the number of platelets(Count). RBC numbers are not useful...instead we use hemoglobin as a better test to reflect any problems with RBCs. ...Read more
+ ANA test, severe neutropenia with large granular lymphocytes, high monocytes and lymphocytes. Osteoarthritis. Bone marrow biopsy negative. Idea?
Does having 1 autoimmune disorder predispose u2 others? Mom with hoshimoto's>psoriatic arthritis>viral hepatitis>acute myeloid leukemia.
Leukemias: Acute leukemias are those with large numbers of immature cells that grow quickly. They can be either myeloid or lymphoid in lineage. Chronic leukemias have more mature cells, a longer course, but can also be myeloid or lymphoid. A hematologist/oncologist is generally the treating physician, and a hematopathologist is the one who give the specific syping. ...Read more
Too many platelets: The myeloproliferative neoplasms (mpns) involve terminal myeloid cell expansion in the peripheral blood, resulting in various combinations of erythrocytosis (rbc's), leukocytosis (wbc's), thrombocytosis (platelets), bone marrow hypercellularity/fibrosis, and splenomegaly (enlarged spleen). Essential thrombocythemia is a diagnosis of exclusion, made when other forms of mpn are ruled out. ...Read more
Help me interpret vulvar biopsy. Focal squamous atypia. Ki-67 shows mild increase cell proliferation focal vin can't be excluded. Lichen sclerosis?
Nothing serious yet: This report suggests slightly abnormal changes (atypia & increased cell proliferation) which can be a reaction to irritation but there is no definitive evidence of precancerous change (VIN). In short there is nothing to worry about right now unless you are concerned and you'd like a second opinion ...Read more
Blood disorder: It is a big group of blood neoplasm - where can be classified further into many different conditions - among of them will include - chronic myelogenous leukemia, polycythemia vera. Essential thrombocythemia, myelofibrosis, chronic eosinophilic leukemia, systemic mastocytosis etc- depending on which clones that are affected . Those conditions can transform into acute leukemia. ...Read moreSee 1 more doctor answer
Hypercellular Marrow,increased Trilineage Hematopoiesis,reactive lymphoplasmacytosis, Erythropoiesis normoblastic and decreased. Myeloblasts not increased Megakaryocytes increased, include young forms
Marrow confusion: Complex because the answer is dependent on the hematologists total examination and not just a marrow. There is a difference between dysmorphic cells and immature forms so no diagnosis can be made from your comments. Stick with the hematologist or concologist. ...Read moreSee 1 more doctor answer
WHAT DOES BENIGN ENDOMETRIUM WITH A PROLIFERATIVE PATTERN, GLANDULAR BREAKDOWN AND DIFFUSE STROMAL BREAKDOWN - SCANT BENIGN ENDOCERVICAL TISSUE MEAN?
No worries!: Benign is normal or "non-cancerous". Proliferative just means the cells are in the phase where they are dividing which is normal during the estrogen part of the cycle. Endocervical tissue is just cells that came from inside the cervix - these were also benign! All good news! ...Read more
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